LT2486051T - Farmacinis preparatas, apimantis rekombinantinį hcg - Google Patents

Farmacinis preparatas, apimantis rekombinantinį hcg

Info

Publication number
LT2486051T
LT2486051T LTEP10763000.6T LT10763000T LT2486051T LT 2486051 T LT2486051 T LT 2486051T LT 10763000 T LT10763000 T LT 10763000T LT 2486051 T LT2486051 T LT 2486051T
Authority
LT
Lithuania
Prior art keywords
pharmaceutical preparation
recombinant hcg
hcg
recombinant
pharmaceutical
Prior art date
Application number
LTEP10763000.6T
Other languages
English (en)
Lithuanian (lt)
Inventor
Ian Cottingham
Daniel Plaksin
Richard White
Original Assignee
Ferring B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring B.V. filed Critical Ferring B.V.
Publication of LT2486051T publication Critical patent/LT2486051T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/99Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTEP10763000.6T 2009-10-05 2010-10-04 Farmacinis preparatas, apimantis rekombinantinį hcg LT2486051T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09252360 2009-10-05
PCT/GB2010/001854 WO2011042688A1 (en) 2009-10-05 2010-10-04 Pharmaceutical preparation comprising recombinant hcg

Publications (1)

Publication Number Publication Date
LT2486051T true LT2486051T (lt) 2020-07-10

Family

ID=41471027

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP10763000.6T LT2486051T (lt) 2009-10-05 2010-10-04 Farmacinis preparatas, apimantis rekombinantinį hcg

Country Status (25)

Country Link
US (5) US8975226B2 (OSRAM)
EP (2) EP2486051B1 (OSRAM)
JP (6) JP6176924B2 (OSRAM)
KR (7) KR102489143B1 (OSRAM)
CN (1) CN107050434B (OSRAM)
AR (2) AR079876A1 (OSRAM)
AU (1) AU2010304922B2 (OSRAM)
BR (1) BR112012007990A2 (OSRAM)
CA (1) CA2776790A1 (OSRAM)
DK (1) DK2486051T3 (OSRAM)
ES (2) ES3036152T3 (OSRAM)
HR (1) HRP20200941T1 (OSRAM)
HU (1) HUE050793T2 (OSRAM)
IL (3) IL218548A (OSRAM)
IN (1) IN2012DN02073A (OSRAM)
JO (1) JOP20200039A1 (OSRAM)
LT (1) LT2486051T (OSRAM)
MX (1) MX2012003951A (OSRAM)
PL (1) PL2486051T3 (OSRAM)
PT (1) PT2486051T (OSRAM)
RS (1) RS60413B1 (OSRAM)
RU (2) RU2724528C2 (OSRAM)
SI (1) SI2486051T1 (OSRAM)
TW (2) TWI604850B (OSRAM)
WO (1) WO2011042688A1 (OSRAM)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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TWI488640B (zh) 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI604850B (zh) * 2009-10-05 2017-11-11 菲瑞茵國際中心股份有限公司 藥學製劑
CN103619358B (zh) 2011-03-31 2017-02-15 辉凌公司 药物制剂
AR090095A1 (es) * 2011-06-06 2014-10-22 Ferring Bv Preparacion farmaceutica que comprende hormona estimulante del foliculo recombinante
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
WO2013093760A2 (en) * 2011-12-19 2013-06-27 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
ES2784510T3 (es) 2012-12-10 2020-09-28 Seikagaku Kogyo Co Ltd Método para producir un nuevo Factor C recombinante, método para mitigar la inhibición de la reacción en ensayos de endotoxina, y método para medir endotoxina
CN107429237B (zh) * 2014-12-22 2021-09-28 豪夫迈·罗氏有限公司 Cmp依赖性的唾液酸酶活性
EA034022B1 (ru) * 2015-04-24 2019-12-19 Ферринг Б.В. Способ получения гонадотропина
JP6845813B2 (ja) 2015-06-26 2021-03-24 フェリング ベスローテン フェンノートシャップ 精製および/またはウイルス不活性化の方法
PL3787667T3 (pl) * 2018-04-30 2025-07-28 Ferring B.V. Kompozycja do kontrolowanej stymulacji jajników
JOP20220174A1 (ar) * 2020-02-05 2023-01-30 Novartis Ag دايمر il-15 غير المتجانس المعبر عنه بواسطة الخلية cho
CN116199742B (zh) * 2022-07-06 2025-01-24 华兰基因工程有限公司 一种重组人绒毛膜促性腺激素Fc融合蛋白制备方法

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CN1302010C (zh) 1997-06-25 2007-02-28 应用研究系统Ars股份公司 二硫键交联的糖蛋白激素类似物及其制备和应用
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BR0010709B1 (pt) 1999-05-07 2011-11-29 uso de lh para a produção de um medicamento para induzir a paucifoliculogênese ou unifoliculogênese em mulheres anovulatórias.
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IL160780A0 (en) 2001-09-12 2004-08-31 Applied Research Systems USE OF hCG IN THE MANUFACTURE OF A MEDICAMENT
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CN100347306C (zh) * 2001-10-29 2007-11-07 克鲁塞尔荷兰公司 生产具有预定的翻译后修饰的蛋白质的方法和手段
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KR100809945B1 (ko) * 2006-02-01 2008-03-05 대한민국 인체장내정상세균총 특이반응 dna칩 및 이를 이용한인체장내정상세균총의 변화에 의한 인체 위해성의 평가방법
CN101516388B (zh) * 2006-07-21 2012-10-31 诺和诺德公司 通过o-联糖基化序列的肽的糖基化
EP2054521A4 (en) * 2006-10-03 2012-12-19 Novo Nordisk As PROCESS FOR CLEANING POLYPEPTIDE CONJUGATES
TWI488640B (zh) * 2008-04-16 2015-06-21 Ferring Int Ct Sa 藥學製劑
TWI604850B (zh) * 2009-10-05 2017-11-11 菲瑞茵國際中心股份有限公司 藥學製劑
CN103619358B (zh) * 2011-03-31 2017-02-15 辉凌公司 药物制剂
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض

Also Published As

Publication number Publication date
BR112012007990A2 (pt) 2017-07-25
JP2016074680A (ja) 2016-05-12
US20130023476A1 (en) 2013-01-24
HRP20200941T1 (hr) 2020-09-18
KR20230012104A (ko) 2023-01-25
SI2486051T1 (sl) 2020-08-31
KR20120094909A (ko) 2012-08-27
TWI604850B (zh) 2017-11-11
US12234272B2 (en) 2025-02-25
KR102489143B1 (ko) 2023-01-13
JP2023075144A (ja) 2023-05-30
RS60413B1 (sr) 2020-07-31
HUE050793T2 (hu) 2021-01-28
JP6310440B2 (ja) 2018-04-11
JP2020000246A (ja) 2020-01-09
EP2486051B1 (en) 2020-03-25
EP3611185A1 (en) 2020-02-19
TWI532495B (zh) 2016-05-11
RU2724528C2 (ru) 2020-06-23
US10526390B2 (en) 2020-01-07
DK2486051T3 (da) 2020-06-22
WO2011042688A1 (en) 2011-04-14
AU2010304922A1 (en) 2012-03-29
JP2018076296A (ja) 2018-05-17
US8975226B2 (en) 2015-03-10
KR20210014767A (ko) 2021-02-09
US11292824B2 (en) 2022-04-05
JP2021176867A (ja) 2021-11-11
CA2776790A1 (en) 2011-04-14
US20200247863A1 (en) 2020-08-06
KR102213154B1 (ko) 2021-02-05
CN102549011A (zh) 2012-07-04
AR125991A2 (es) 2023-08-30
US20140249082A1 (en) 2014-09-04
KR20170133531A (ko) 2017-12-05
IL250733A0 (en) 2017-04-30
US20180030107A1 (en) 2018-02-01
AU2010304922B2 (en) 2014-11-06
ES2798258T3 (es) 2020-12-10
IL218548A (en) 2017-03-30
KR20190067256A (ko) 2019-06-14
PT2486051T (pt) 2020-06-17
JP6580104B2 (ja) 2019-09-25
JP7196244B2 (ja) 2022-12-26
CN107050434A (zh) 2017-08-18
RU2588650C2 (ru) 2016-07-10
IN2012DN02073A (OSRAM) 2015-08-21
JP7292153B2 (ja) 2023-06-16
KR101987982B1 (ko) 2019-06-11
KR20190028823A (ko) 2019-03-19
AR079876A1 (es) 2012-02-29
PL2486051T3 (pl) 2020-09-07
IL267556A (en) 2019-08-29
RU2016118236A (ru) 2018-10-29
JP6176924B2 (ja) 2017-08-09
EP2486051A1 (en) 2012-08-15
CN107050434B (zh) 2021-07-27
KR101804479B1 (ko) 2017-12-05
TW201113030A (en) 2011-04-16
RU2012112907A (ru) 2013-11-10
IL218548A0 (en) 2012-05-31
IL250733B (en) 2019-07-31
EP3611185B1 (en) 2025-04-30
TW201632198A (zh) 2016-09-16
US20220340634A1 (en) 2022-10-27
JOP20200039A1 (ar) 2022-10-30
RU2016118236A3 (OSRAM) 2019-09-18
US9676835B2 (en) 2017-06-13
JP2013506708A (ja) 2013-02-28
ES3036152T3 (en) 2025-09-15
MX2012003951A (es) 2012-05-29
KR20210141771A (ko) 2021-11-23

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