ES2166841T3 - Formulaciones liquidas de hcg. - Google Patents

Formulaciones liquidas de hcg.

Info

Publication number
ES2166841T3
ES2166841T3 ES95944848T ES95944848T ES2166841T3 ES 2166841 T3 ES2166841 T3 ES 2166841T3 ES 95944848 T ES95944848 T ES 95944848T ES 95944848 T ES95944848 T ES 95944848T ES 2166841 T3 ES2166841 T3 ES 2166841T3
Authority
ES
Spain
Prior art keywords
hcg
soln
liquid formulations
polyalcohol
mannitol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95944848T
Other languages
English (en)
Inventor
Fabrizio Samaritani
Patrizia Natale
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Research Systems ARS Holding NV
Original Assignee
Applied Research Systems ARS Holding NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems ARS Holding NV filed Critical Applied Research Systems ARS Holding NV
Application granted granted Critical
Publication of ES2166841T3 publication Critical patent/ES2166841T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPOSICIONES FARMACEUTICAS LIQUIDAS, QUE CONTIENEN GONADOTROPINA CORIONICA HUMANA (HCG) ESTABILIZADA CON UN POLIALCOHOL O UN AZUCAR NO REDUCTOR. PREFERIBLEMENTE, DICHAS COMPOSICIONES SE ESTABILIZAN CON MANITOL. EN LAS REALIZACIONES PREFERIDAS, DICHAS COMPOSICIONES SON SOLUCIONES ACUOSAS EN TAMPON FOSFATO A PH 7. DICHAS COMPOSICIONES ESTAN LISTAS PARA INYECTAR Y, POR TANTO, SE EVITA LA FASE DE RECONSTITUCION DEL POLVO LIOFILIZADO, SIMPLIFICANDO POR TANTO EL PROCEDIMIENTO DE UTILIZACION.
ES95944848T 1995-03-21 1995-03-21 Formulaciones liquidas de hcg. Expired - Lifetime ES2166841T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1995/001055 WO1996029095A1 (en) 1995-03-21 1995-03-21 Hcg liquid formulations

Publications (1)

Publication Number Publication Date
ES2166841T3 true ES2166841T3 (es) 2002-05-01

Family

ID=8165977

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95944848T Expired - Lifetime ES2166841T3 (es) 1995-03-21 1995-03-21 Formulaciones liquidas de hcg.

Country Status (16)

Country Link
US (1) US6706681B1 (es)
EP (1) EP0814841B1 (es)
JP (1) JP4165718B2 (es)
KR (1) KR100377967B1 (es)
AT (1) ATE209930T1 (es)
AU (1) AU707796B2 (es)
BR (1) BR9510567A (es)
DE (1) DE69524456T2 (es)
DK (1) DK0814841T3 (es)
ES (1) ES2166841T3 (es)
FI (1) FI117160B (es)
HK (1) HK1006365A1 (es)
NO (1) NO318997B1 (es)
PT (1) PT814841E (es)
UA (1) UA61053C2 (es)
WO (1) WO1996029095A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319504B1 (en) 1996-06-24 2001-11-20 University Of Maryland Biotechnology Institute Treatment and prevention of HIV infection by administration of derivatives of human chorionic gonadotropin
IL122732A0 (en) * 1997-01-15 1998-08-16 Akzo Nobel Nv Liquid gonadotropin-containing formulation its preparation and a device containing same
KR100548107B1 (ko) * 1997-01-30 2006-02-02 바이오팜 게젤샤프트 쭈어 바이오테히놀로지셴 엔트비클룽 폰 파르마카 엠베하 뼈 유도 인자 인간 ｍｐ52 동결 건조 조성물
CN100482679C (zh) 2000-02-22 2009-04-29 雪兰诺实验室有限公司 人绒毛膜促性腺激素的纯化方法
WO2002011753A1 (fr) * 2000-08-04 2002-02-14 Chugai Seiyaku Kabushiki Kaisha Preparations proteiniques a injecter
FR2869979B1 (fr) * 2004-05-06 2006-08-04 Packinox Sa Echangeur thermique a plaques
KR101105871B1 (ko) * 2005-09-27 2012-01-16 주식회사 엘지생명과학 인 난포자극호르몬의 안정한 용액 제형
KR20080106636A (ko) * 2007-06-04 2008-12-09 동아제약주식회사 사람 융모성 성선자극호르몬 함유 즉시 사용형 주사 용액
MY153976A (en) * 2007-11-01 2015-04-30 Merck Serono Sa Lh liquid formulations
TWI532495B (zh) * 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
WO2011108010A2 (en) * 2010-03-05 2011-09-09 Intas Biopharmaceuticals Limited A thermostable liquid formulation of gonadotropins
EP2417982A1 (en) 2010-07-30 2012-02-15 Ferring B.V. Stabilization of gonadotropins
US20120265129A1 (en) 2011-04-15 2012-10-18 Neuralight Hd, Llc Methods for Chronic Pain Management and Treatment using HCG
US8680086B2 (en) 2011-04-15 2014-03-25 Neuralight Hd, Llc Methods for chronic pain management and treatment using HCG
MX2015004940A (es) 2012-10-18 2015-12-09 Neuralight Hd Llc Tratamiento de depresion y ptsd.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL88233A (en) * 1987-11-03 1993-08-18 Genentech Inc Gamma interferon formulation
IE64738B1 (en) * 1990-03-20 1995-09-06 Akzo Nv Stabilized gonadotropin containing preparations
US5385230A (en) * 1991-01-11 1995-01-31 Minnesota Mining And Manufacturing Company Adjustable tray assembly for use in desk drawers
JP2966592B2 (ja) * 1991-07-20 1999-10-25 萩原 義秀 安定化されたヒトモノクローナル抗体製剤
IT1250075B (it) * 1991-12-18 1995-03-30 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti gonadotropine.

Also Published As

Publication number Publication date
US6706681B1 (en) 2004-03-16
KR19980702859A (ko) 1998-08-05
ATE209930T1 (de) 2001-12-15
HK1006365A1 (en) 1999-02-26
PT814841E (pt) 2002-03-28
WO1996029095A1 (en) 1996-09-26
DK0814841T3 (da) 2002-03-04
DE69524456D1 (de) 2002-01-17
NO974309L (no) 1997-10-14
NO318997B1 (no) 2005-05-30
EP0814841A2 (en) 1998-01-07
JP4165718B2 (ja) 2008-10-15
DE69524456T2 (de) 2002-08-01
AU707796B2 (en) 1999-07-22
JPH11502205A (ja) 1999-02-23
FI973745A (fi) 1997-11-11
NO974309D0 (no) 1997-09-18
EP0814841B1 (en) 2001-12-05
FI973745A0 (fi) 1997-09-22
FI117160B (fi) 2006-07-14
UA61053C2 (en) 2003-11-17
KR100377967B1 (ko) 2003-06-12
BR9510567A (pt) 1998-06-23
AU2110695A (en) 1996-10-08

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