KR960034349A - 점착성 기제 - Google Patents

점착성 기제 Download PDF

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Publication number
KR960034349A
KR960034349A KR1019960008401A KR19960008401A KR960034349A KR 960034349 A KR960034349 A KR 960034349A KR 1019960008401 A KR1019960008401 A KR 1019960008401A KR 19960008401 A KR19960008401 A KR 19960008401A KR 960034349 A KR960034349 A KR 960034349A
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KR
South Korea
Prior art keywords
meth
acrylate
adhesive base
agents
base according
Prior art date
Application number
KR1019960008401A
Other languages
English (en)
Inventor
토시오 이나기
마코토 가네바코
Original Assignee
미와 요시히로
코와 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 미와 요시히로, 코와 가부시키가이샤 filed Critical 미와 요시히로
Publication of KR960034349A publication Critical patent/KR960034349A/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/24—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J133/00—Adhesives based on homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Adhesives based on derivatives of such polymers
    • C09J133/04—Homopolymers or copolymers of esters
    • C09J133/06—Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
    • C09J133/062—Copolymers with monomers not covered by C09J133/06
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 글루코실옥시 알킬(메타)아크릴레이트, 히드록시알킬(메타)아크릴레이트, 알킬(메타)아크릴레이트 및 다관능성 모노머를 중합시켜 얻어진 폴리머를 함유하는 점착성 기제를 개시한다. 본 점착성 기제는 팽윤성이 양호하여 균일하게 팽윤할 수 있으며, 더욱이 피부에 대하여 우수한 점착성을 나타내기 때문에 플래스터의 점착층, 각종 의료용 패드, 약제를 함침시킨 피부외용제 등으로 유용하다.

Description

점착성 기제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (13)

  1. 글루코실옥시 알킬(메타)아클릴레이트, 히드록시알킬(메타)아클릴레이트, 알킬(메타)아크릴레이트 및 다관능성 모노머를 중합시켜 얻어진 폴리머를 함유하는 점착성 기제.
  2. 제1항에 있어서, 글루코실옥시 알킬(메타)아클릴레이트, 히드록시알킬(메타)아클릴레이트 및 알킬(메타)아크릴레이트의 몰비가 0.1~10 : 10~40 : 5~20인 것이 특징인 점착성 기제.
  3. 제1항에 있어서, 다관능성 모노마와, 글루코실옥시 알킬(메타)아클릴레이트, 히드록시알킬(메타)아크릴레이트, 알킬(메타)아크릴레이트의 합계량과의 몰비가 1 : 100 내지 1 : 3200인 것이 특징인 점착성 기제.
  4. 글루코실옥시 에틸(메타)아클릴레이트, 2-히드록시에틸(메타)아클릴레이트, n-부틸(메타)아크릴레이트 및 에틸렌 글리콜 디(메타)아크릴레이트를 중합시켜 얻어진 폴리머를 함유하는 점착성 기제.
  5. 제1 내지 제4항의 어느 한 항에 있어서, 폴리머가 다가 알코올 및 물의 혼합 용매를 함침시킨 것이 특징인 점착성 기제.
  6. 제5항에 있어서, 폴리머가 다가 알코올, 1가 알코올 및 물의 혼합용매를 함침시킨 것이 특징인 점착성 기제.
  7. 제6항에 있어서, 다가 알코올, 1가 알코올 및 물이 0.5~5 : 0.1~2 : 1의 중량빌 혼합된 것이 특징인 점착성 기제.
  8. 제5 내지 7항의 어느 한 항에 있어서, 폴리머가 미분쇄된 것이 특징인 점착성 기제.
  9. 제8항에 있어서, 알코올과 물이 1 : 1 내지 1 : 100의 중량비로 혼합된 것이 특징인 점착성 기제.
  10. 제5 내지 9항의 어느 한 항에 있어서, 용매를 함침하여 팽윤한 폴리머의 팽윤율이 300% 이상인 것이 특징인 점착성 기제.
  11. 제10항에 있어서, 폴리머의 글래스에 대한 박리강도가 80g/cm2인 것이 특징인 점착성 기제.
  12. 제1항 내지 11항의 어느 한 항에 따른 점착성 기제 및 약제를 함유하는 피부외용제.
  13. 제12항에 있어서, 약제가 해열 소염진통제, 스테로이드계항염증제, 혈관화장제, 항고혈압부정맥제, 혈압강하체, 진해거담제, 항종양제, 호르몬제, 항천식알레르기제, 항히스타민제, 항응혈제, 진경제, 뇌순환대사개선제, 항우울증, 항불만제, 비타민 D제, 혈당강하제, 항궤양제, 수면제, 항생물질인 피부외용제.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019960008401A 1995-03-31 1996-03-26 점착성 기제 KR960034349A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP75050/1995 1995-03-31
JP7505095 1995-03-31

Publications (1)

Publication Number Publication Date
KR960034349A true KR960034349A (ko) 1996-10-22

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ID=13564995

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019960008401A KR960034349A (ko) 1995-03-31 1996-03-26 점착성 기제

Country Status (6)

Country Link
US (1) US5646221A (ko)
EP (1) EP0735122B1 (ko)
KR (1) KR960034349A (ko)
AT (1) ATE209670T1 (ko)
CA (1) CA2172690A1 (ko)
DE (1) DE69617302T2 (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69614942T2 (de) * 1995-07-04 2002-04-04 Kowa Co., Ltd. Hydrophiles Klebemittel
SE9604610D0 (sv) * 1996-12-16 1996-12-16 Noviscens Ab Medical composition
US20040044080A1 (en) * 1997-10-28 2004-03-04 Place Virgil A. Treatment of dyspareunia with topically administered nitroglycerin formulations
US8287483B2 (en) 1998-01-08 2012-10-16 Echo Therapeutics, Inc. Method and apparatus for enhancement of transdermal transport
US20060015058A1 (en) * 1998-01-08 2006-01-19 Kellogg Scott C Agents and methods for enhancement of transdermal transport
US7066884B2 (en) * 1998-01-08 2006-06-27 Sontra Medical, Inc. System, method, and device for non-invasive body fluid sampling and analysis
JP2000169825A (ja) * 1998-12-10 2000-06-20 Minnesota Mining & Mfg Co <3M> 接着剤組成物および接着シート
US6627688B1 (en) 1998-12-10 2003-09-30 3M Innovative Properties Company Adhesive compositions and adhesive sheets
US20040171980A1 (en) 1998-12-18 2004-09-02 Sontra Medical, Inc. Method and apparatus for enhancement of transdermal transport
DE10252978A1 (de) * 2002-11-14 2004-06-03 Lohmann Gmbh & Co Kg Chemisch inerter Haftkleber mit verbesserter Haftung, Verfahren zu seiner Herstellung und Verwendung
US8224414B2 (en) * 2004-10-28 2012-07-17 Echo Therapeutics, Inc. System and method for analyte sampling and analysis with hydrogel
US7432069B2 (en) * 2005-12-05 2008-10-07 Sontra Medical Corporation Biocompatible chemically crosslinked hydrogels for glucose sensing
CA2680213C (en) 2007-03-07 2014-10-14 Echo Therapeutics, Inc. Transdermal analyte monitoring systems and methods for analyte detection
DK2152358T3 (da) 2007-04-27 2011-06-27 Echo Therapeutics Inc Hudgennemtrængningsindretning til analytmåling og transdermal medicinafgivelse
BR112015028040A2 (pt) * 2013-05-06 2018-04-24 The Regents Of The Univ Of Minnesota polímero contendo cadeia principal derivada de acrilato, métodos para preparar polímeros, formulações farmacêuticas e métodos para aumentar a solubilidade de um fármaco
US11130890B2 (en) * 2015-01-21 2021-09-28 Toyo Ink Sc Holdings Co., Ltd. Adhesive composition, adhesive sheet, and method for producing same
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
KR102565565B1 (ko) * 2015-02-06 2023-08-09 노벤 파머수티컬즈, 인코퍼레이티드 경피 약물 전달용 감압 접착제

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5173554A (en) * 1988-10-27 1992-12-22 Nippon Fine Chemical Co., Ltd. Glycoside derivatives, polymers containing glycoside derivatives, process for their preparation, and use of said polymers
JPH03193057A (ja) * 1989-12-22 1991-08-22 Nippon Fine Chem Co Ltd 医療用粘着剤組成物
US5164495A (en) * 1991-09-18 1992-11-17 Abbott Laboratories Method for preparing a dicarboxylic acid half-acid ester of FK506

Also Published As

Publication number Publication date
DE69617302D1 (de) 2002-01-10
US5646221A (en) 1997-07-08
EP0735122A3 (en) 1998-09-30
EP0735122A2 (en) 1996-10-02
EP0735122B1 (en) 2001-11-28
DE69617302T2 (de) 2002-05-08
ATE209670T1 (de) 2001-12-15
CA2172690A1 (en) 1996-10-01

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