KR960007526B1 - 2-피리미디닐-1-피페라진 유도체를 함유하는 약제학적 조성물 - Google Patents

2-피리미디닐-1-피페라진 유도체를 함유하는 약제학적 조성물 Download PDF

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Publication number
KR960007526B1
KR960007526B1 KR1019880010516A KR880010516A KR960007526B1 KR 960007526 B1 KR960007526 B1 KR 960007526B1 KR 1019880010516 A KR1019880010516 A KR 1019880010516A KR 880010516 A KR880010516 A KR 880010516A KR 960007526 B1 KR960007526 B1 KR 960007526B1
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South Korea
Prior art keywords
pyrimidinyl
piperazine derivatives
pharmaceutical compositions
compositions containing
piperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1019880010516A
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English (en)
Korean (ko)
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KR890003752A (ko
Inventor
트라버 외르그
오피츠 클라우스
Original Assignee
게르트 바딕케; 하르트무트 클리미쉬
트로폰베르케 지엠비에이치 앤드 캄파니 케이지
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Publication of KR890003752A publication Critical patent/KR890003752A/ko
Application granted granted Critical
Publication of KR960007526B1 publication Critical patent/KR960007526B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019880010516A 1987-08-21 1988-08-19 2-피리미디닐-1-피페라진 유도체를 함유하는 약제학적 조성물 Expired - Fee Related KR960007526B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP3727879.7 1987-08-21
DE19873727879 DE3727879A1 (de) 1987-08-21 1987-08-21 Verwendung von 2-pyrimidinyl-1-piperazin-derivaten
DE3727879 1987-08-21

Publications (2)

Publication Number Publication Date
KR890003752A KR890003752A (ko) 1989-04-17
KR960007526B1 true KR960007526B1 (ko) 1996-06-05

Family

ID=6334172

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880010516A Expired - Fee Related KR960007526B1 (ko) 1987-08-21 1988-08-19 2-피리미디닐-1-피페라진 유도체를 함유하는 약제학적 조성물

Country Status (16)

Country Link
US (1) US4895848A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0303951B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JP2618449B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR960007526B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE81976T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU600852B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1313499C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE3727879A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK467988A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2052650T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI883867A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR3006293T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU199684B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE62077B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL87490A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH26797A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4782060A (en) * 1987-07-29 1988-11-01 Bristol-Myers Company Gepirone for alleviation of panic disorders
US5106849A (en) * 1988-05-24 1992-04-21 American Home Products Corporation Use of aryl- and heteroaryl piperazinyl carboxamides in the treatment of various central nervous system disorders
IL91451A0 (en) * 1988-08-30 1990-04-29 Bristol Myers Co Pharmaceutical compositions comprising azapiron compounds and their use in the treatment of addiction
EP0376633B1 (en) * 1988-12-28 1994-10-12 Suntory Limited Benzoxazepine derivatives
WO1992000075A1 (en) * 1990-06-29 1992-01-09 Pfizer Inc. Pyridopyrazine derivatives for treating substance abuse and addiction
US5366990A (en) * 1991-11-14 1994-11-22 Reid Larry D Method for treating alcohol abuse and alcoholism
US5183819A (en) * 1992-05-11 1993-02-02 American Home Products Corporation Use of fused bicyclic imides in the treatment of various CNS disorders
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
ES2183726B1 (es) * 2001-07-05 2004-07-01 Garbil Pharma Investigacion Chile Ltda. Compuestos utiles para el tratamiento del alcoholismo.
US7041320B1 (en) 2002-05-31 2006-05-09 Biotek, Inc. High drug loaded injectable microparticle compositions and methods of treating opioid drug dependence
US7157102B1 (en) 2002-05-31 2007-01-02 Biotek, Inc. Multi-layered microcapsules and method of preparing same

Also Published As

Publication number Publication date
ES2052650T3 (es) 1994-07-16
EP0303951A2 (de) 1989-02-22
DK467988D0 (da) 1988-08-19
HU199684B (en) 1990-03-28
CA1313499C (en) 1993-02-09
AU600852B2 (en) 1990-08-23
FI883867L (fi) 1989-02-22
KR890003752A (ko) 1989-04-17
DE3727879A1 (de) 1989-03-02
JP2618449B2 (ja) 1997-06-11
EP0303951B1 (de) 1992-11-04
DK467988A (da) 1989-02-22
FI883867A7 (fi) 1989-02-22
EP0303951A3 (en) 1990-07-04
US4895848A (en) 1990-01-23
IE62077B1 (en) 1994-12-14
AU2118588A (en) 1989-02-23
PH26797A (en) 1992-10-13
GR3006293T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1993-06-21
HUT47430A (en) 1989-03-28
ATE81976T1 (de) 1992-11-15
JPS6468368A (en) 1989-03-14
IE882544L (en) 1989-02-21
FI883867A0 (fi) 1988-08-19
IL87490A0 (en) 1989-01-31
DE3875670D1 (de) 1992-12-10

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