KR960004486B1 - Chinese medicin soap composition - Google Patents
Chinese medicin soap composition Download PDFInfo
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- KR960004486B1 KR960004486B1 KR1019930012528A KR930012528A KR960004486B1 KR 960004486 B1 KR960004486 B1 KR 960004486B1 KR 1019930012528 A KR1019930012528 A KR 1019930012528A KR 930012528 A KR930012528 A KR 930012528A KR 960004486 B1 KR960004486 B1 KR 960004486B1
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- South Korea
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- soap composition
- herbal
- weight
- soap
- peony
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- 239000000344 soap Substances 0.000 title claims abstract description 38
- 239000000203 mixture Substances 0.000 title claims abstract description 26
- 239000000284 extract Substances 0.000 claims abstract description 17
- 241000736199 Paeonia Species 0.000 claims abstract description 15
- 239000000843 powder Substances 0.000 claims abstract description 15
- 235000006484 Paeonia officinalis Nutrition 0.000 claims description 13
- 241000209020 Cornus Species 0.000 claims description 12
- 239000002537 cosmetic Substances 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 7
- 239000003205 fragrance Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 238000011282 treatment Methods 0.000 abstract description 11
- 241000186427 Cutibacterium acnes Species 0.000 abstract description 9
- 230000002265 prevention Effects 0.000 abstract description 8
- 239000002304 perfume Substances 0.000 abstract description 5
- QFOHBWFCKVYLES-UHFFFAOYSA-N Butylparaben Chemical compound CCCCOC(=O)C1=CC=C(O)C=C1 QFOHBWFCKVYLES-UHFFFAOYSA-N 0.000 abstract description 4
- LXCFILQKKLGQFO-UHFFFAOYSA-N methylparaben Chemical compound COC(=O)C1=CC=C(O)C=C1 LXCFILQKKLGQFO-UHFFFAOYSA-N 0.000 abstract description 4
- -1 phosphoric acid salt Chemical class 0.000 abstract description 4
- 239000002260 anti-inflammatory agent Substances 0.000 abstract description 3
- 239000003963 antioxidant agent Substances 0.000 abstract description 3
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 abstract description 2
- 241000759833 Cornus officinalis Species 0.000 abstract description 2
- 241000143634 Ligusticum tenuissimum Species 0.000 abstract description 2
- 241001474977 Palla Species 0.000 abstract description 2
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 abstract description 2
- 229940067596 butylparaben Drugs 0.000 abstract description 2
- ONTQJDKFANPPKK-UHFFFAOYSA-L chembl3185981 Chemical compound [Na+].[Na+].CC1=CC(C)=C(S([O-])(=O)=O)C=C1N=NC1=CC(S([O-])(=O)=O)=C(C=CC=C2)C2=C1O ONTQJDKFANPPKK-UHFFFAOYSA-L 0.000 abstract description 2
- 239000004292 methyl p-hydroxybenzoate Substances 0.000 abstract description 2
- 235000010270 methyl p-hydroxybenzoate Nutrition 0.000 abstract description 2
- 229960002216 methylparaben Drugs 0.000 abstract description 2
- 229940055019 propionibacterium acne Drugs 0.000 abstract description 2
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 abstract description 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- 230000001741 anti-phlogistic effect Effects 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 238000004040 coloring Methods 0.000 abstract 1
- 230000002070 germicidal effect Effects 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N phosphoric acid Substances OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 16
- 206010000496 acne Diseases 0.000 description 16
- 230000000844 anti-bacterial effect Effects 0.000 description 10
- 239000004615 ingredient Substances 0.000 description 9
- 210000003491 skin Anatomy 0.000 description 8
- 206010040880 Skin irritation Diseases 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000036556 skin irritation Effects 0.000 description 5
- 231100000475 skin irritation Toxicity 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 238000005336 cracking Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 210000002374 sebum Anatomy 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 206010012442 Dermatitis contact Diseases 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- YTZSBJLNMIQROD-SFBCHFHNSA-N Morroniside Chemical compound O([C@@H]1OC=C([C@H]2C[C@H](O)O[C@@H](C)[C@H]21)C(=O)OC)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O YTZSBJLNMIQROD-SFBCHFHNSA-N 0.000 description 2
- 239000003098 androgen Substances 0.000 description 2
- 229940121363 anti-inflammatory agent Drugs 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 208000010247 contact dermatitis Diseases 0.000 description 2
- 235000021588 free fatty acids Nutrition 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- LNTHITQWFMADLM-UHFFFAOYSA-N gallic acid Chemical compound OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 2
- 210000003780 hair follicle Anatomy 0.000 description 2
- BDJRBEYXGGNYIS-UHFFFAOYSA-N nonanedioic acid Chemical compound OC(=O)CCCCCCCC(O)=O BDJRBEYXGGNYIS-UHFFFAOYSA-N 0.000 description 2
- ZRSNZINYAWTAHE-UHFFFAOYSA-N p-methoxybenzaldehyde Chemical compound COC1=CC=C(C=O)C=C1 ZRSNZINYAWTAHE-UHFFFAOYSA-N 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
- 210000001732 sebaceous gland Anatomy 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- YTZSBJLNMIQROD-UHFFFAOYSA-N (4aS)-1c-beta-D-glucopyranosyloxy-6xi-hydroxy-8t-methyl-(4ar,8ac)-5,6,8,8a-tetrahydro-1H,4aH-pyrano[3,4-c]pyran-4-carboxylic acid methyl ester Natural products C12C(C)OC(O)CC2C(C(=O)OC)=COC1OC1OC(CO)C(O)C(O)C1O YTZSBJLNMIQROD-UHFFFAOYSA-N 0.000 description 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 1
- IQVQXVFMNOFTMU-FLIBITNWSA-N (Z)-ligustilide Chemical compound C1CC=CC2=C1C(=C/CCC)/OC2=O IQVQXVFMNOFTMU-FLIBITNWSA-N 0.000 description 1
- QQUHMASGPODSIW-UHFFFAOYSA-N Albiflorin Natural products C=1C=CC=CC=1C(=O)OCC12C(=O)OC3(C)CC(O)C1CC32OC1OC(CO)C(O)C(O)C1O QQUHMASGPODSIW-UHFFFAOYSA-N 0.000 description 1
- 241000208173 Apiaceae Species 0.000 description 1
- 239000005711 Benzoic acid Substances 0.000 description 1
- 239000004342 Benzoyl peroxide Substances 0.000 description 1
- OMPJBNCRMGITSC-UHFFFAOYSA-N Benzoylperoxide Chemical compound C=1C=CC=CC=1C(=O)OOC(=O)C1=CC=CC=C1 OMPJBNCRMGITSC-UHFFFAOYSA-N 0.000 description 1
- 241001164374 Calyx Species 0.000 description 1
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 1
- 241000142975 Cornaceae Species 0.000 description 1
- 235000017788 Cydonia oblonga Nutrition 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 206010020649 Hyperkeratosis Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000001126 Keratosis Diseases 0.000 description 1
- AMBQHHVBBHTQBF-UHFFFAOYSA-N Loganin Natural products C12C(C)C(O)CC2C(C(=O)OC)=COC1OC1OC(CO)C(O)C(O)C1O AMBQHHVBBHTQBF-UHFFFAOYSA-N 0.000 description 1
- YKRGDOXKVOZESV-WRJNSLSBSA-N Paeoniflorin Chemical compound C([C@]12[C@H]3O[C@]4(O)C[C@](O3)([C@]1(C[C@@H]42)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O)C)OC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-WRJNSLSBSA-N 0.000 description 1
- VSJGJMKGNMDJCI-ZASXJUAOSA-N Sweroside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](C=C)[C@H](CCOC2=O)C2=CO1 VSJGJMKGNMDJCI-ZASXJUAOSA-N 0.000 description 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 description 1
- IQVQXVFMNOFTMU-DHZHZOJOSA-N Z-ligustilide Natural products C1CC=CC2=C1C(=C/CCC)\OC2=O IQVQXVFMNOFTMU-DHZHZOJOSA-N 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- QQUHMASGPODSIW-ICECTASOSA-N albiflorin Chemical compound O([C@@]12C[C@H]3[C@H](O)C[C@@]1(OC(=O)[C@]32COC(=O)C=1C=CC=CC=1)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O QQUHMASGPODSIW-ICECTASOSA-N 0.000 description 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 229960002255 azelaic acid Drugs 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- 235000019400 benzoyl peroxide Nutrition 0.000 description 1
- 229960003328 benzoyl peroxide Drugs 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 235000011869 dried fruits Nutrition 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000003925 fat Substances 0.000 description 1
- 210000000185 follicular epithelial cell Anatomy 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- AMBQHHVBBHTQBF-UOUCRYGSSA-N loganin Chemical compound O([C@@H]1OC=C([C@H]2C[C@H](O)[C@H](C)[C@H]21)C(=O)OC)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O AMBQHHVBBHTQBF-UOUCRYGSSA-N 0.000 description 1
- 239000001630 malic acid Substances 0.000 description 1
- 235000011090 malic acid Nutrition 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- YKRGDOXKVOZESV-UHFFFAOYSA-N paeoniflorin Natural products O1C(C)(C2(CC34)OC5C(C(O)C(O)C(CO)O5)O)CC3(O)OC1C24COC(=O)C1=CC=CC=C1 YKRGDOXKVOZESV-UHFFFAOYSA-N 0.000 description 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
- 125000002467 phosphate group Chemical class [H]OP(=O)(O[H])O[*] 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 229930002330 retinoic acid Natural products 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 235000019614 sour taste Nutrition 0.000 description 1
- VSJGJMKGNMDJCI-QXSNVGMTSA-N sweroside Natural products OC[C@H]1O[C@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](O)[C@@H](O)[C@@H]1O VSJGJMKGNMDJCI-QXSNVGMTSA-N 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 239000000052 vinegar Substances 0.000 description 1
- 235000021419 vinegar Nutrition 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/22—Organic compounds, e.g. vitamins
- C11D9/38—Products in which the composition is not well defined
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D13/00—Making of soap or soap solutions in general; Apparatus therefor
- C11D13/10—Mixing; Kneading
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D9/00—Compositions of detergents based essentially on soap
- C11D9/04—Compositions of detergents based essentially on soap containing compounding ingredients other than soaps
- C11D9/44—Perfumes; Colouring materials; Brightening agents ; Bleaching agents
- C11D9/442—Perfumes
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D2111/00—Cleaning compositions characterised by the objects to be cleaned; Cleaning compositions characterised by non-standard cleaning or washing processes
- C11D2111/10—Objects to be cleaned
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
Description
본 발명은 피부의 여드름 예방 및 치료효과가 우수한 한방 생약성분의 추출액 및/또는 분말을 첨가하여서된 한방비누 조성물 및 그의 제조방법에 관한 것이다.The present invention relates to a herbal soap composition prepared by adding an extract and / or powder of herbal herbal ingredients excellent in preventing and treating acne on the skin, and a method of manufacturing the same.
일반적으로 여드름은 얼굴이나 가슴, 목, 어깨 등의 상단부에 발생하는 염증성 질환으로 주로 10대 초반에 시작하여 20대 후반까지 지속되는데, 그 이후에도 종종 40대까지 여드름이 생성되는 것을 볼 수 있다. 여드름의 발병원인은 확실치 않으나, 다양한 인자가 관여하리라 추정된다. 그러나 근본적으로 피지선을 자극하는 호르몬인 안드로겐(androgen)과 모피지선(毛皮脂膳)에서 번식하여 피지를 분해하고 유리지방산을 생성하는 프로피오니박테리움 아크네(propionibacterium acnes)가 가장 중요한 두가지 요인으로 추정된다. 즉, 안드로겐에 의해 피지선이 비대해지고 피지분비가 왕성해지며 모낭벽세포(follicular epithelial cell)에 이상각화가 일어나 모낭구가 막혀 피지가 배출되지 못하여 정체되고 여기에 혐기성 여드름균(P.acnes)이 번식하여 지방을 분해, 유리지방산을 형성한다. 유기지방산은 모낭벽을 직접 자극하고 진피내로도 들어가 염증을 일으킨다.In general, acne is an inflammatory disease that occurs in the upper part of the face, chest, neck, shoulders, etc. It mainly begins in the early teens and lasts until the late twenties. After that, acne is often produced until the forties. The cause of acne is not clear, but a variety of factors may be involved. However, the most important two factors are androgen, a hormone that stimulates sebaceous glands, and propionibacterium acnes, which break down sebum and produce free fatty acids. . In other words, the androgen causes sebaceous glands to become enlarged and sebum secretion becomes vigorous, and abnormal keratosis occurs in the follicular epithelial cells, causing the hair follicles to be blocked and stagnating because sebum is not discharged. It breaks down fats and forms free fatty acids. Organofatty acids directly stimulate the hair follicle wall and enter the dermis and cause inflammation.
여드름을 치료하는 방법에는 직접 피부에 크림이나 액상의 치료제, 예를 들어 트리클로로카본, 살리실산, 아젤라산, 벤조일퍼옥사이드, 레티온산 등을 도포하는 경우와 항생제(tetracycline)를 복용하는 경우가 있다. 그러나 이들 화합물은 천연물이 아닌 합성 화학물질이기 때문에 피부에 직접 도포할 경우 피부에 심한 자극을 주어 접촉 피부염을 유발시키는 경우가 있다.Treatments for acne include the application of creams or liquid therapeutic agents directly to the skin, such as trichlorocarbon, salicylic acid, azelaic acid, benzoyl peroxide, retinoic acid, and antibiotics. However, these compounds are synthetic chemicals, not natural ones, and when applied directly to the skin, it may cause severe irritation to the skin, causing contact dermatitis.
따라서, 본 발명의 목적은 이러한 문제점을 해결하기 위하여 합성화학물질이 아닌 접촉 피부염을 유발시키지 않는 천연 한방 생약성분인 산수유, 작약, 고본을 사용하여 여드름 예방 및 치료효과가 우수한 한방비누조성물을 제공하는데 있다.Accordingly, an object of the present invention is to provide a herbal nasal composition excellent in acne prevention and treatment effect by using a natural herbal herbal ingredients such as cornus, peony, and medicinal herbs that do not cause contact dermatitis but not synthetic chemicals to solve these problems. have.
본 발명은 산수유, 작약 및 고본 중에서 선택된 1종 또는 2종 이상의 추출액 및/또는 분말을 0.1 내지 9중량% 함유함을 특징으로 하는 한방비누조성물에 관한 것이다.The present invention relates to a herbal soap composition comprising 0.1 to 9% by weight of one or two or more extracts and / or powders selected from Cornus, Peony and Gobon.
또한 본 발명은 산수유, 작약 및 고본 중에서 선택된 1종 또는 2종 이상의 추출액 및/또는 0.1 내지 9중량%를 화장비누베이스(수분 14중량% 포함) 및 함료와 혼합시킴을 특징으로 하는 한방비누조성물의 제조방법에 관한 것이다.In addition, the present invention is a herbal soap composition characterized by mixing one or two or more extracts and / or 0.1 to 9% by weight selected from cornus oil, peony and hard bone with a cosmetic soap base (including 14% by weight of moisture) and the content It relates to a manufacturing method.
본 발명에서 사용된 한방 생약성분은 다음과 같다.Herbal herbal ingredients used in the present invention are as follows.
(1) 산수유(山茱萸)(1) Sansuyu
① 학명 : 코너스 오피시날리스 에스. 에트제트. (Cornus officinalis S. et Z.)① Scientific name: Conners Officesinus S. Etjet. Cornus officinalis S. et Z.
② 기원 : 충충나무과(Cornaceae)에 속하는 산수유의 과실을 건조한 것② Origin: Dried fruits of Cornus quince belonging to the Cornaceae family
③ 성상 : 편압(扁壓)된 긴 타원형이고, 길이 1.5-2.0cm, 너비 약 1cm이다. 바깥면은 어두운 적자색-어두운 자색을 띠며 윤이나고 거친 주름이 있으며 씨를 뺀 찢어진 자국이 있고 윗쪽에 꽃받침의 자국이 있으며 기부에 과병의 자국이 있다. 이 약은 약간 특이한 냄새가 있고 신맛이 있으며 약간 달다.③ Appearance: It is a long oval that is biased (扁 壓), 1.5-2.0cm long, about 1cm wide. The outer surface is dark reddish purple-dark purple with shiny, rough wrinkles, ripped tears from seeds, traces of calyx on the upper part, and traces of fruit on the base. The drug has a slightly unusual smell, has a sour taste and is slightly sweet.
④ 성분 : 로가닌(loganin), 스웨로시드(sweroside), 모로니시드(morroniside), 갈산(gallic acid), 말산(malic acid), 타타르산(tartaric acid)④ Ingredients: Loganin, sweroside, swroniside, morroniside, gallic acid, malic acid, tartaric acid
⑤ 약리작용 : 항염증작용, 항균작용, 살균작용, 수렴작용, 여드름 예방 및 치료.⑤ pharmacological action: anti-inflammatory, antibacterial, bactericidal, astringent, acne prevention and treatment.
(2) 작약(芍藥)(2) Peony
① 학명 : 락티플로라 패오니아 팔라스(Lactiflora paeonia pallas)① Scientific name: Lactiflora paeonia pallas
② 기원 : 미나리아재비과(Ranunculaceae)에 속하는 작약의 뿌리를 건조한 것.② Origin: Dried roots of peony belonging to Ranunculuaceae.
③ 성상 : 원주상-원추상으로서 길이 7-20cm, 지름 10-25cm이며 큰것은 세로로 쪼갠것도 있다. 바깥면은 갈색-엷은 회갈색으로서 세로주름이 뚜렷하고 측근이 붙어있던 자리와 가로의 피복이 있으며 때로는 왼쪽끝에 움푹한 줄기의 자국이 있다. 꺾은면은 가루상이고 치밀하여 확대경으로 보면 회갈색이고 목부에는 엷은 갈색의 방사선이 있다. 이 약은 특이한 향기가 있으며 맛은 처음에는 달고 나중에는 약간 떫고 쓰다.③ Appearance: columnar-conical, 7-20cm long, 10-25cm in diameter, larger ones are also split vertically. The outer surface is brownish-light grayish brown with clear vertical wrinkles, abutment and horizontal coverings, and sometimes a dent on the left end. Folded face is powdery, dense, grayish brown in magnifier, light brown neck. The drug has an unusual scent and tastes sweet at first and slightly steamed and bitter later.
④ 성분 : 패오니플로린(Paeoniflorin), 패오닌(Paeonine), 벤조산, 탄닌, 알비플로린(Albiflorin)④ Ingredients: Paeoniflorin, Paeonine, Benzoic Acid, Tannin, Albiflorin
⑤ 약리작용 : 항염증작용, 항균작용, 살균작용, 소염작용, 미백, 보습작용, 멜라닌 색소 생성 억제작용, 여드름 예방 및 치료⑤ pharmacological action: anti-inflammatory, antibacterial, bactericidal, anti-inflammatory, whitening, moisturizing, melanin pigment production inhibitory, acne prevention and treatment
(3) 고본(藁本)(3) Old book
① 학명 : 안젤리카 테누이시마 나카이(Angelica tenuissima NAKAI)① Scientific name: Angelica tenuissima NAKAI
② 기원 : 미나리과(Umbelliferae)에 속하는 고본의 뿌리를 건조한 것.② Origin: Dried roots of Gobon belonging to the family Umbelliferae.
③ 성상 : 길이 약 5-6cm, 지름 10mm가량이고 뿌리의 바깥면은 어두운 갈색을 띠고 추근은 박추형으로 여러개의 가지뿌리가 갈라져 있으며 근두부에는 줄기 및 엽초의 잔기가 붙어 있다. 이 약은 특이한 방향성 냄새가 있고 맛은 쓰고 뒤에는 약간 아리다.③ Appearance: about 5-6cm long, 10mm in diameter, the outer surface of the root is dark brown, the roots are pepper-shaped, several branched roots are split, and the root and stem are attached to the residues of stems and vinegar. The drug has an unusual aromatic smell, tastes bitter, and a little behind.
④ 성분 : 리거스틸리드(Ligustilide), 센큐노이스(Senkyunoid) 부틸리덴프탈리드(Butylidenphthalide), 에스드라고울(Esdragole), 아니살데히드(Anisaldehyde), 노토스미르놀(Nothosmyrnol)④ Ingredients: Ligustilide, Senkyyunoid Butyllidenphthalide, Butdraulle, Anisaldehyde, Notthosmyrnol
⑤ 약리작용 : 항균작용, 피부윤택, 여드름 예방 및 치료⑤ Pharmacological action: antibacterial effect, skin shine, acne prevention and treatment
본 발명에 따른 한방비누조성물은 산수유, 작약 및 고본 중에서 선택된 1종 또는 2종 이상의 추출액 및/ 또는 분말을 0.1 내지 9중량% 함유하는 것이 바람직하다. 상기 성분을 0.1중량% 미만 사용할 경우 피부의 여드름 예방 및 치료효과가 미약하게 되고, 9중량% 이상 사용할때에는 여드름 예방 및 치료효과는 우수하나 물침적후 갈라지는 현상이 심하고 피부에 대한 자극이 심하다.The herbal soap composition according to the present invention preferably contains 0.1 to 9% by weight of one or two or more extracts and / or powders selected from Cornus, Peony and Gobon. If the component is used less than 0.1% by weight of the skin acne prevention and treatment effect is weak, when using more than 9% by weight is excellent acne prevention and treatment effect but severe cracking after water deposition and severe irritation to the skin.
본 발명에서 약효성분으로 사용되는 산수유, 작약, 고본 추출액 및/또는 분말은 꽃, 잎, 줄기 및 뿌리로부터 얻은 것이 바람직하다.Cornus oil, peony, medicinal extract and / or powder used as the active ingredient in the present invention is preferably obtained from flowers, leaves, stems and roots.
본 발명에 따른 한방비누 제품은 통상적인 방법에 의해 제조할 수 있다. 예를 들면 일반 화장비누베이스에 산수유, 작약 및 고본 중에서 선택된 1종 또는 2종 이상의 추출액 및/또는 분말을 향료와 함께 혼합시켜 제조할 수 있다. 필요에 따라 색소, 살균제, 소염제, 산화방지제, 방부제등을 추가할 수 있으며 또한 물성 개선을 위해 무기염류 및 합성고분자 물질을 사용할 수도 있다.Herbal soap products according to the present invention can be prepared by conventional methods. For example, it may be prepared by mixing one or two or more extracts and / or powders selected from Cornus, Peony and Kobon with fragrance in a general cosmetic soap base. If necessary, pigments, fungicides, anti-inflammatory agents, antioxidants, and preservatives may be added, and inorganic salts and synthetic polymer materials may be used to improve physical properties.
본 발명의 제조방법에서 사용가능한 살균제 및 소염제로는 상품명 TCC, Irgasan DP-300 등이 있고, 산화방지제로는 EDTA 4Na, BHT 및 인산염등이 있고, 색소로는 Red 4, Fa Yellow, Fa Green 등이 있고, 방부제로는 메틸파라벤, 부틸파라벤 등이 있다.The fungicides and anti-inflammatory agents that can be used in the preparation method of the present invention include trade names TCC, Irgasan DP-300, etc., antioxidants include EDTA 4Na, BHT, and phosphate salts, and pigments such as Red 4, Fa Yellow, Fa Green, etc. Preservatives include methyl paraben, butyl paraben and the like.
이하 본 발명을 실시예에 의거하여 구체적으로 설명한다.Hereinafter, the present invention will be described in detail with reference to Examples.
[실시예 1]Example 1
산수유 단독 사용시When using cornus oil alone
화장비누 베이스 98.9중량%(수분 14중량% 포함)와 산수유 추출액 및/또는 분말 0.1중량%를 혼합기에서 잘 혼합한 후 비누 제조 기계에서 압출, 절단, 형타하여 고형 비누 형태의 한반비누 조성물을 제조하였다.98.9% by weight of the cosmetic soap base (including 14% by weight of moisture) and 0.1% by weight of cornus extract and / or powder were mixed well in a mixer, and then extruded, cut, and molded in a soap manufacturing machine to prepare a Korean soap composition in the form of a solid soap. .
[실시예 8]Example 8
작약 단독 사용시When using peony alone
화장비누 베이스 98.9중량%(수분 14중량% 포함)와 작약 추출액 및/또는 분말 0.1중량%, 향료 1중량%를 혼합하여 상기 실시예 1과 동일한 방법으로 한방 비누 조성물을 제조하였다.A herbal soap composition was prepared in the same manner as in Example 1 by mixing 98.9% by weight of a cosmetic soap base (including 14% by weight of water), 0.1% by weight of peony extract and / or powder, and 1% by weight of perfume.
[실시예 15]Example 15
고본 단독 사용시When using the original alone
화장비누 베이스 98.9중량%(수분 14중량% 포함)와 고본 추출액 및/또는 분말 0.1중량%, 향료 1중량%를 혼합하여 상기 실시예 1과 동일한 방법으로 한방 비누 조성물을 제조하였다.A herbal soap composition was prepared in the same manner as in Example 1 by mixing 98.9% by weight of a cosmetic soap base (including 14% by weight of moisture), 0.1% by weight of a solid extract and / or powder, and 1% by weight of perfume.
상기 실시예 및 비교예에서 제조한 한방비누 조성물에 대하여 여드름 치료효과의 균열도 및 피부 자극도를 확인하기 위하여 다음과 같은 방법으로 확인하여 보았다.The herbal soap compositions prepared in Examples and Comparative Examples were checked in the following manner to determine the degree of cracking and skin irritation of the acne treatment effect.
1. 여드름균(P.acnes)에 대한 살균력 실험1. Test of bactericidal power against P.acnes
진공하에서 페트리 디쉬(박테리아 배양용 접시)에 혐기성 여드름균(P.acnes)을 배양하여 5%의 실시예 및 비교예 비누 수용액을 떨어뜨린 후 3일간 경과후 집락수를 측정하여 평가하였다. 여드름균(P.acnes) 살균효과를 측정하기 위하여 아래와 같이 살균율을 구한다.Anaerobic acne bacteria (P.acnes) were incubated in a Petri dish (bacterial dish) under vacuum, and 5% of the Examples and Comparative Soaps were dropped, and colony counts were measured after 3 days. In order to measure the bactericidal effect of P. acnes, the sterilization rate is calculated as follows.
여드름균(P.acnes)의 살균율은 90% 이상이 되어야 효과가 있는 것으로 판단된다.P. acnes sterilization rate of more than 90% is believed to be effective.
실시예 1 내지 21 및 비교예 1 내지 9의 한방비누조성물의 여드름균(P.acnes)에 대한 살균력 실험결과는 다음 표와 같다.The bactericidal force test results of P. acnes of herbal soaps of Examples 1 to 21 and Comparative Examples 1 to 9 are shown in the following table.
산수유 단독 사용시 When using cornus oil alone
작약 단독 사용시 Peony alone
고본 단독 사용시 When using the original alone
2. 균열도 실험2. Crack Test
제조 후 24시간 이상이 경과한 화장비누를 비누의 가로 방향으로 약 2cm되는 지점에 핀을 꽂은 후 25℃의 항온 수조에 수면에서 수직으로 4시간 동안 물에 침적시킨 후 꺼내어 21 내지 25℃, 50 내지 60%의 절대습도를 유지하는 곳에서 24 내지 36시간 건조시킨 후 다음 평가표에 따라 균열도를 측정하였다.After 24 hours of manufacture, put a pin on the point about 2cm in the transverse direction of the soap after 24 hours elapsed, and then immersed in water at a constant temperature water bath at 25 ° C. for 4 hours vertically from the water and then taken out from 21 to 25 ° C., 50 After drying for 24 to 36 hours at the absolute humidity of 60 to 60%, the crack was measured according to the following evaluation table.
균열도 평가표 Crack chart
3. 피부 자극도 실험3. Skin irritation test
자극성 시험용 반창고를 이용하여 화장비누 조성물 5% 수용액을 반창고의 거즈 부분에 1ml 흡수시킨 후 사람의 팔 윗부분에서 붙인다. 붙인 후 48시간이 경과하여 반창고를 제거하고 1시간 후 피부를 관찰하였다. 평가방법은 아래 평가표에 의해 평가하였다.A 5% aqueous soap composition was applied to the gauze portion of the band-aid using a band-aid for irritation test, and then attached on the upper part of the human arm. After 48 hours, the bandage was removed and the skin was observed after 1 hour. The evaluation method was evaluated by the following evaluation table.
피부 자극도 평가표 Skin irritation evaluation table
판정은 20명을 대상으로 실험하여 그 결과를 평가하였다.The judgment was conducted on 20 people and the results were evaluated.
실시예 1 내지 21 및 비교예 1 내지 9의 한방비누조성물의 균열도 및 피부 자극도에 대한 실험결과는 다음과 같다.Experimental results on the degree of cracking and skin irritation of the herbal soap composition of Examples 1 to 21 and Comparative Examples 1 to 9 are as follows.
산수유 단독 사용시 When using cornus oil alone
작약 단독 사용시 Peony alone
고본 단독 사용시 When using the original alone
[실시예 22]Example 22
한방 생약성분을 혼합 사용했을 경우When herbal medicines are mixed
화장비누 베이스 93중량%(수분 14중량% 포함)와 산수유 3중량%, 작약 3중량%, 향료 1중량%, 향료 1중량%를 혼합하여 상기 실시예 1과 동일한 방법으로 한방비누 조성물을 제조하였다.Herbal soap composition was prepared in the same manner as in Example 1 by mixing 93% by weight of the soap base (including 14% by weight of moisture), 3% by weight of cornus oil, 3% by weight of peony, 1% by weight of perfume, and 1% by weight of perfume. .
상기 실시예에서 제조한 한방비누 조성물에 대하여 단독으로 사용했을 때와 동일한 방법으로 여드름균(P.acnes)의 살균효과 및 균열도, 피부자극도를 측정해 보았다. 그 결과는 다음 표과 같다.The bactericidal effect, cracking degree, and skin irritation degree of acne bacteria (P. acnes) were measured in the same manner as when used alone. The results are shown in the following table.
여드름균(P.acnes)에 대한 살균력 비교 Comparison of bactericidal power against P.acnes
이상의 실시예 및 비교예에서 보는 바와 같이 한방 생약성분을 단독으로 사용했을때 여드름에 대한 우수한 치료효과를 기대할 수 있다. 그러나 두가지 및 세가지 한방 생약성분을 혼합 사용했을 경우가 각 성분의 상승효과로 인해 단독으로 사용했을 경우 보다 여드름에 대한 예방 및 치료효과가 월등히 우수한 것을 알 수 있다.As seen in the above Examples and Comparative Examples when using the herbal herbal ingredients alone can be expected excellent treatment effect for acne. However, when the two and three herbal herbal ingredients are used in combination, it can be seen that the prevention and treatment of acne is much better than when used alone due to the synergistic effect of each ingredient.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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KR100467031B1 (en) * | 1996-12-11 | 2005-06-17 | 주식회사 엘지생활건강 | Acne prevention and treatment composition |
KR100883690B1 (en) * | 2007-04-13 | 2009-02-18 | 김성진 | Cleanser composition comprising herb extracts and manufacturing method thereof |
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KR100523540B1 (en) * | 1997-12-23 | 2006-01-12 | 주식회사 엘지생활건강 | Composition Inhibiting Activity of 5α-Reductase and Antimicrobial Activity to Propionibacterium Acnes |
KR100966525B1 (en) * | 2009-06-16 | 2010-06-29 | 퀄리플로나라테크 주식회사 | The process chamber protective system of a single crystal silicon ingot grower |
KR102267541B1 (en) | 2019-09-27 | 2021-06-21 | 주식회사 지가미 | Soap manufacturing method that can effectively increase the amount of high functional raw material to improve cleaning and whitening effect |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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KR100467031B1 (en) * | 1996-12-11 | 2005-06-17 | 주식회사 엘지생활건강 | Acne prevention and treatment composition |
KR100883690B1 (en) * | 2007-04-13 | 2009-02-18 | 김성진 | Cleanser composition comprising herb extracts and manufacturing method thereof |
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