KR950700928A - 타키키닌 길항 활성을 갖는 펩타이드(peptides having tachykinin antagonist activity) - Google Patents

타키키닌 길항 활성을 갖는 펩타이드(peptides having tachykinin antagonist activity)

Info

Publication number
KR950700928A
KR950700928A KR1019940703682A KR19940703682A KR950700928A KR 950700928 A KR950700928 A KR 950700928A KR 1019940703682 A KR1019940703682 A KR 1019940703682A KR 19940703682 A KR19940703682 A KR 19940703682A KR 950700928 A KR950700928 A KR 950700928A
Authority
KR
South Korea
Prior art keywords
peptide
antagonist activity
tachykinin antagonist
compounds
image
Prior art date
Application number
KR1019940703682A
Other languages
English (en)
Other versions
KR100250921B1 (ko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR950700928A publication Critical patent/KR950700928A/ko
Application granted granted Critical
Publication of KR100250921B1 publication Critical patent/KR100250921B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
KR1019940703682A 1992-04-21 1993-04-09 타키키닌 길항활성을 갖는 펩타이드 KR100250921B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/871,723 US5420297A (en) 1990-10-24 1992-04-21 Peptides having substance P antagonistic activity
US7/871723 1992-04-21
PCT/JP1993/000470 WO1993021215A1 (en) 1992-04-21 1993-04-09 Peptides having tachykinin antagonist activity

Publications (2)

Publication Number Publication Date
KR950700928A true KR950700928A (ko) 1995-02-20
KR100250921B1 KR100250921B1 (ko) 2000-04-01

Family

ID=25357987

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940703682A KR100250921B1 (ko) 1992-04-21 1993-04-09 타키키닌 길항활성을 갖는 펩타이드

Country Status (17)

Country Link
US (2) US5420297A (ko)
EP (1) EP0640099B1 (ko)
JP (1) JPH07505879A (ko)
KR (1) KR100250921B1 (ko)
CN (1) CN1041830C (ko)
AT (1) ATE205852T1 (ko)
AU (1) AU674512B2 (ko)
CA (1) CA2118503A1 (ko)
DE (1) DE69330788T2 (ko)
ES (1) ES2160103T3 (ko)
HU (2) HUT71397A (ko)
IL (1) IL105404A (ko)
MX (1) MX9302178A (ko)
RU (1) RU2119922C1 (ko)
TW (1) TW314525B (ko)
WO (1) WO1993021215A1 (ko)
ZA (1) ZA932728B (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5654400A (en) * 1991-10-04 1997-08-05 Fujisawa Pharmaceutical Co., Ltd. Process for making peptide compounds having tachykinin antagonistic activity
WO1994020126A1 (en) * 1993-03-03 1994-09-15 Fujisawa Pharmaceutical Co., Ltd. Use of peptides for the manufacture of a medicament
WO1995000536A1 (en) * 1993-06-22 1995-01-05 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds
EP0672678B1 (en) * 1994-03-17 2000-10-25 Fujirebio Inc. Azapeptide derivative
DE19512484A1 (de) 1995-04-04 1996-10-17 Bayer Ag Kohlenhydratmodifizierte Cytostatika
US6284226B1 (en) * 1997-03-14 2001-09-04 Fujisawa Pharmaceutical Co., Ltd. Aerosol composition containing middle-chain fatty acid triglyceride dispersant
AU1600599A (en) 1998-02-27 1999-09-15 Warner-Lambert Company Heterocyclic substituted aniline calcium channel blockers
US6166052A (en) 1998-03-11 2000-12-26 Warner-Lambert Company Heteroaryl alkyl alpha substituted peptidylamine calcium channel blockers
US6399629B1 (en) * 1998-06-01 2002-06-04 Microcide Pharmaceuticals, Inc. Efflux pump inhibitors
AU7311100A (en) * 1999-09-14 2001-04-17 Fujisawa Pharmaceutical Co., Ltd. Novel processes for the production of peptide compounds
US6437093B1 (en) 2000-11-28 2002-08-20 Milkhaus Laboratory, Inc. Methods of treatment comprising administration of Substance P
GB0223077D0 (en) * 2002-10-04 2002-11-13 Univ Reading The Treatment of vascular diseases
TW200500341A (en) * 2002-11-12 2005-01-01 Astrazeneca Ab Novel compounds
CA2628179A1 (en) 2005-11-15 2007-05-24 Vertex Pharmaceuticals Incorporated Azaindazoles useful as inhibitors of kinases
EA008737B1 (ru) * 2005-12-07 2007-08-31 Леонид Андреевич Кожемякин Средство для профилактики и лечения конъюнктивитов и кератитов различной этиологии (варианты), способ его применения
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
DE202011000090U1 (de) 2011-01-14 2011-04-21 E-LEAD ELECTRONIC CO., LTD., Shengang Shiang Fahrzeug-Audiosystem mit auswechselbarem Plug-In-Computer
IT1403659B1 (it) * 2011-01-28 2013-10-31 Kerakoll S P A Stucco epossidico a base acquosa
EP2729147B1 (en) 2011-07-04 2017-09-06 IRBM - Science Park S.p.A. Nk-1 receptor antagonists for treating corneal neovascularisation
AU2012311098B2 (en) * 2011-09-24 2014-06-12 Electrical And Electronics, Ltd. Beverage system with aeration
US20210015834A1 (en) 2018-02-26 2021-01-21 Ospedale San Raffaele S.R.L. Nk-1 antagonists for use in the treatment of ocular pain
WO2021180885A1 (en) 2020-03-11 2021-09-16 Ospedale San Raffaele S.R.L. Treatment of stem cell deficiency

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187156A (en) * 1988-03-16 1993-02-16 Fujisawa Pharmaceutical Co., Ltd. Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same
US5164372A (en) * 1989-04-28 1992-11-17 Fujisawa Pharmaceutical Company, Ltd. Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
GB8929070D0 (en) * 1989-12-22 1990-02-28 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
WO1991012266A1 (en) * 1990-02-15 1991-08-22 Fujisawa Pharmaceutical Co., Ltd. Peptide compound
GB9023116D0 (en) * 1990-10-24 1990-12-05 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
RU94045881A (ru) 1996-09-10
KR100250921B1 (ko) 2000-04-01
RU2119922C1 (ru) 1998-10-10
ATE205852T1 (de) 2001-10-15
AU674512B2 (en) 1997-01-02
IL105404A (en) 1999-11-30
IL105404A0 (en) 1993-08-18
EP0640099A1 (en) 1995-03-01
CN1041830C (zh) 1999-01-27
DE69330788D1 (de) 2001-10-25
CN1083074A (zh) 1994-03-02
US5633232A (en) 1997-05-27
JPH07505879A (ja) 1995-06-29
ES2160103T3 (es) 2001-11-01
MX9302178A (es) 1994-06-30
HU211831A9 (en) 1995-12-28
DE69330788T2 (de) 2002-05-29
EP0640099B1 (en) 2001-09-19
HU9403062D0 (en) 1994-12-28
US5420297A (en) 1995-05-30
CA2118503A1 (en) 1993-10-28
HUT71397A (en) 1995-11-28
ZA932728B (en) 1993-10-28
AU3904593A (en) 1993-11-18
WO1993021215A1 (en) 1993-10-28
TW314525B (ko) 1997-09-01

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E902 Notification of reason for refusal
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
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