KR950700051A - 구강제제 조성물 - Google Patents

구강제제 조성물

Info

Publication number
KR950700051A
KR950700051A KR1019940702955A KR19940702955A KR950700051A KR 950700051 A KR950700051 A KR 950700051A KR 1019940702955 A KR1019940702955 A KR 1019940702955A KR 19940702955 A KR19940702955 A KR 19940702955A KR 950700051 A KR950700051 A KR 950700051A
Authority
KR
South Korea
Prior art keywords
composition
melting point
basic
functional polymer
weight
Prior art date
Application number
KR1019940702955A
Other languages
English (en)
Other versions
KR100218700B1 (ko
Inventor
도시오 야지마
구니아키 이시이
노부오 우메키
시게루 이타이
히데후미 하야시
기미히데 시마노
이쿠오 고야마
Original Assignee
우에하라 아키라
다이쇼 세이야쿠 가부시키가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 우에하라 아키라, 다이쇼 세이야쿠 가부시키가이샤 filed Critical 우에하라 아키라
Priority claimed from PCT/JP1993/000291 external-priority patent/WO1993017667A1/en
Publication of KR950700051A publication Critical patent/KR950700051A/ko
Application granted granted Critical
Publication of KR100218700B1 publication Critical patent/KR100218700B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

불쾌한 맛이 나는 기초약품과 기능성 폴리머 화합물을 저융점 물질, 전조성에 대해 10∼70중량%의 당알코올 및 전조성에 대해 0.1∼7중량%의 염기성 산화물에 분산 또는 용해시켜 얻어진 컴플렉스로 구성된 경구제제용 조성물을 제공한다.

Description

구강제제 조성물
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 10분 경과시까지의 각 피험조성물에 대한 평가결과를 나타내는 그래프이다.

Claims (8)

  1. 불쾌한 맛이 나는 기초약품과 기능성 폴리머 화합물을 저융점 물질, 전조성에 대해 10∼70중량%의 당알코올 및 전조성에 대해 0.1∼7중량%의 염기성 산화물에 분산 또는 용해시켜 얻어진 컴플렉스로 구성된 경구제제용 조성물.
  2. 제1항에 있어서, 컴플렉스가 저융점의 가열용융 물질과 기초약품에 분산 또는 용해된 기능성 폴리머 화합물을 용융 또는 가열 조립하여 얻어진 생성물인 조성물.
  3. 제1항에 있어서, 기능성 폴리머 화합물이 컴플렉스에 대해 1∼60중량% 함유된 조성물.
  4. 제1항에 있어서, 기초약품이 불쾌한 맛을 마크로라이드의 1종인 조성물.
  5. 제1항에 있어서, 기능성 폴리머가 EudragitE 및 AEA로 부터 선택된 적어도 1종인 조성물.
  6. 제1항에 있어서, 저융점 물질이 40∼120℃의 융점을 가지며 물에 불용성이거나 난용성인 약학적으로 허용되는 물질인 조성물.
  7. 제1항에 있어서, 염기성 산화물이 산화마그네슘인 조성물.
  8. 건조시럽형태인 제1항의 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019940702955A 1992-03-12 1993-03-10 경구용조성물 KR100218700B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP53442/1992 1992-03-12
JP5344204 1992-03-12
JP4-53442 1992-03-12
JP219904/1992 1992-08-19
JP21990404 1992-08-19
JP4-219904 1992-08-19
PCT/JP1993/000291 WO1993017667A1 (en) 1992-03-12 1993-03-10 Composition for oral preparations

Publications (2)

Publication Number Publication Date
KR950700051A true KR950700051A (ko) 1995-01-16
KR100218700B1 KR100218700B1 (ko) 1999-09-01

Family

ID=66659763

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019940702955A KR100218700B1 (ko) 1992-03-12 1993-03-10 경구용조성물

Country Status (1)

Country Link
KR (1) KR100218700B1 (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100768034B1 (ko) * 1999-03-17 2007-10-17 다이이찌 세이야꾸 가부시기가이샤 의약 조성물

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100768034B1 (ko) * 1999-03-17 2007-10-17 다이이찌 세이야꾸 가부시기가이샤 의약 조성물

Also Published As

Publication number Publication date
KR100218700B1 (ko) 1999-09-01

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