KR940010903A - 치환된 벤즈이미다졸의 용도 - Google Patents

치환된 벤즈이미다졸의 용도 Download PDF

Info

Publication number
KR940010903A
KR940010903A KR1019930023236A KR930023236A KR940010903A KR 940010903 A KR940010903 A KR 940010903A KR 1019930023236 A KR1019930023236 A KR 1019930023236A KR 930023236 A KR930023236 A KR 930023236A KR 940010903 A KR940010903 A KR 940010903A
Authority
KR
South Korea
Prior art keywords
optionally substituted
het
alkyl
substituted
aryl
Prior art date
Application number
KR1019930023236A
Other languages
English (en)
Other versions
KR100278207B1 (ko
Inventor
룬켄하이머 빈프리이드
바스너 베른트
리이브 폴커
하버코른 악셀
Original Assignee
클라우스 대너·귄터 슈마허
바이엘 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 클라우스 대너·귄터 슈마허, 바이엘 악티엔게젤샤프트 filed Critical 클라우스 대너·귄터 슈마허
Publication of KR940010903A publication Critical patent/KR940010903A/ko
Application granted granted Critical
Publication of KR100278207B1 publication Critical patent/KR100278207B1/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A01N43/52—1,3-Diazoles; Hydrogenated 1,3-diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C25—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES; APPARATUS THEREFOR
    • C25B—ELECTROLYTIC OR ELECTROPHORETIC PROCESSES FOR THE PRODUCTION OF COMPOUNDS OR NON-METALS; APPARATUS THEREFOR
    • C25B1/00—Electrolytic production of inorganic compounds or non-metals
    • C25B1/01—Products
    • C25B1/02—Hydrogen or oxygen
    • C25B1/04—Hydrogen or oxygen by electrolysis of water
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/30—Hydrogen technology
    • Y02E60/36—Hydrogen production from non-carbon containing sources, e.g. by water electrolysis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Electrochemistry (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

본 발명은 기생성 원생동물 및 특히는 콕시디아를 구제하기 위한 제제로서의 하기 일반식(I)의 치환된 벤즈이미다졸의 용도에 관한 것이다.
상기식에서, X1, X2, X3및 R4는 각 경우에 서로 독립적으로 수소, 할로겐, 시아노 또는 니트로를 나타내거나, 각 경우에 임의로 치환된 알킬, 알콕시, 알킬티오, 알킬설피닐, 알킬 설포닐 또는 사이클로알킬을 나타내거나, 임의로 치환된 융합 디옥시알킬렌을 나타내거나, 하이드록시카보닐, 알킬카보닐, 알콕시카보닐 또는 사이클로알킬옥시카보닐을 나타내거나, 각 경우에 임의로 치환된 아미노 또는 아미노카보닐을 나타내거나, 각 경우에 임의로 치환된 아릴, 아릴옥시, 아릴티오, 아릴설피닐, 아릴설포닐, 아릴설포릴옥시, 아릴카보닐, 아릴옥시카보닐, 아일라조 또는 아릴티오메틸설포닐을 나타내고 단 치환체 X1, X2, X3및 X4중의 적어도 하나는 수소 및 할로겐이 아니며, R3는 플루오로알킬을 나타내고, R5는 OH, CN. NH2, 사이클로알킬, 알케닐, 알키닐, 알콕시, 할로게노알콕시, 알킬티오, 할로게노알킬티오, 알켄옥시, 알킨옥시, 아미노카보닐, 임의로 치환된 알콕시 카보닐(alkO-CO-), 임의로 치환된 알콕시카보닐옥시(alkOCoo-), 임의로 치환된 (헤트-)아릴, 임의로 치환된(헤트-) 아릴옥시, 임의로 치환된(헤트-)아릴티오, 임의로 치환된(혜트-)아릴설포닐, 디알콕시포스포닐((O 알킬)2,), 임의로 치환된 알킬카보닐(-CO-알킬), 임의로 치환된(헤트-)아릴카보닐(-CO-아릴), 임의로 치환된(헤트-)아릴옥시카보닐(아릴 O-CO-), 임의로 치환된(헤트-)아릴카보닐옥시(아릴COO-), 아미노설포닐(-SO2NH2), 임의로 치환된 모노- 또는 디알킬아미노설포닐, 아실화아미노 또는 모노알킬아미노 및 임의로 치환된 디알킬아미노로 구성된 그룹중에서 선택된 동일하거나 상이한 치환체에 의해 일치환되거나 디치환된 알킬을 나타내거 또는 임의로 치환된 알록시카보닐, 임의로 치환된 (헤트-)아릴옥시카보닐, (헤트-)아릴설포닐, (헤트-)아릴아미노카보닐아미노카보닐옥시 (아릴NH-CO-NH-COO-) 또는 -SO2-NR1-R2를 나타내며, 여기에서 R1및 R2는 수소, 또는 R5대해 상기 언급한 래디칼중의 하나 이상의 래디칼에 의해 임의로 치환된 알킬을 나타낸다.

Description

치환된 벤즈이미다졸의 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (5)

  1. 기생성 원생동물 및 특히는 콕시디아를 구제하기 위한 제제로서의 일빈식(I)의 치환된 벤즈이미다졸의 용도
    상기식에서, X1, X2, X3및 R4는 각 경우에 서로 독립적으로 수소, 할로겐, 시아노 또는 니트로를 나타내거나, 각 경우에 임의로 치환된 알킬, 알콕시, 알킬티오, 알킬설피닐, 알킬 설포닐 또는 사이클로알킬을 나타내거나, 임의로 치환된 융합 디옥시알킬렌을 나타내거나, 하이드록시카보닐, 알킬카보닐, 알콕시카보닐 또는 사이클로알킬옥시카보닐을 나타내거나, 각 경우에 임의로 치환된 아미노 또는 아미노카보닐을 나타내거나, 각 경우에 임의로 치환된 아릴, 아릴옥시, 아릴티오, 아릴설피닐, 아릴설포닐, 아릴설포릴옥시, 아릴카보닐, 아릴옥시카보닐, 아일라조 또는 아릴티오메틸설포닐을 나타내고, 단 치환체 X1, X2, X3및 X4중의 적어도 하나는 수소 및 할로겐이 아니며, R3는 플루오로알킬을 나타내고, R5는 OH, CN, NH2, 사이클로알킬, 알케닐, 알키닐, 알콕시, 할로게노알콕시, 알킬티오, 할로게노알킬티오, 알켄옥시, 알킨옥시, 아미노카보닐, 임의로 치환된 알콕시 카보닐(alkO-CO-), 임의로 치환된 알콕시카보닐옥시(alkOCOO-), 임의로 치환된(헤트-)아릴, 임의로 치환된(헤트-)아릴옥시, 임의로 치환된(헤트-)아릴티오, 임의로 치환된(헤트-)아릴설포닐, 디알콕시포스포닐((O 알킬)2), 임의로 치환된 알킬카보닐(-CO-알킬), 임의로 치환된(헤트-)아릴카보닐(-CO-아릴) , 임의로 치환된(헤트-)아릴옥시카보닐(아릴 O-CO-), 임의로 치환된(헤트-)아릴카보닐옥시(아릴COO-), 아미노설포닐(-SO2NH2), 임의로 치환된 모노- 또는 디알킬아미노설포닐, 아실화아미노 또는 모노알킬아미노 및 임의로 치환된 디알킬아미노로 구성된 그룹중에서 선택된 동일하거나 상이한 치환체에 의해 일치환되거나 디치환된 알킬을 나타내거 또는 임의로 치환된 알록시카보닐, 임의로 치환된(헤트-)아릴옥시카보닐, (헤트-)아릴설포닐, (헤트-)아릴아미노카보닐아미노카보닐옥시(아릴NH-CO-NH-COO-) 또는 -SO2,-NR1-R2를 나타내며, 여기에서 R1및 R2는 수소, 또는 R5에 대해 상기 언급한 래디칼중의 하나 이상의 래디칼에 의해 임의로 치환된 알킬을 나타낸다.
  2. 제1항에 따르는 일반식(I)의 치환된 벤즈이미다졸을 적어도 하나 함유함을 특징으로 하는 기생성 원생동물에 대한 제제.
  3. 제1항에 따르는 일반식(I)의 치환된 벤즈이미다졸을 기생성 원생동물 및/또는 그들의 환경에 작용시킴을 특징으로 하는 기생성 원생동물을 구제하는 방법.
  4. 제1항에 따르는 일반식(I)의 치환된 벤즈이미다졸을 중량제 및/또는 계면 활성제와 혼합함을 특징으로 하는 기생성 원생동물을 구제하는 방법.
  5. 기생성 원생동물에 대한 제제를 제조하기 위한 재1항에 따르는 일반식(I)의 치환된 벤즈이미다졸의 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930023236A 1992-11-06 1993-11-03 치환된 벤즈이미다졸의 용도 KR100278207B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4237617.3 1992-11-06
DE4237617A DE4237617A1 (de) 1992-11-06 1992-11-06 Verwendung von substituierten Benzimidazolen
DEP4337617.3 1992-11-06

Publications (2)

Publication Number Publication Date
KR940010903A true KR940010903A (ko) 1994-06-20
KR100278207B1 KR100278207B1 (ko) 2001-01-15

Family

ID=6472331

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930023236A KR100278207B1 (ko) 1992-11-06 1993-11-03 치환된 벤즈이미다졸의 용도

Country Status (10)

Country Link
US (1) US5482956A (ko)
EP (1) EP0597304B1 (ko)
JP (1) JPH06219946A (ko)
KR (1) KR100278207B1 (ko)
AU (1) AU670317B2 (ko)
DE (2) DE4237617A1 (ko)
DK (1) DK0597304T3 (ko)
ES (1) ES2154641T3 (ko)
GR (1) GR3035574T3 (ko)
TW (1) TW264388B (ko)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19519821A1 (de) * 1995-05-31 1996-12-05 Bayer Ag Mittel gegen parasitäre Protozoen
FR2739255B1 (fr) * 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
CZ158299A3 (cs) 1996-11-15 1999-09-15 Darwin Discovery Limited Bicyklické arylkarboxyamidy a jejich terapeutické použití
DE19831985A1 (de) * 1998-07-16 2000-01-20 Bayer Ag Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
DE19920551A1 (de) 1999-05-05 2000-11-09 Bayer Ag Substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
SE9903894D0 (sv) * 1999-10-28 1999-10-28 New Pharma Research Ab Novel compounds
US6448281B1 (en) 2000-07-06 2002-09-10 Boehringer Ingelheim (Canada) Ltd. Viral polymerase inhibitors
WO2002005649A1 (fr) * 2000-07-13 2002-01-24 Meiji Seika Kaisha, Ltd. Parasiticide et procede antiparasite
DE10049468A1 (de) * 2000-10-06 2002-04-11 Bayer Ag N-Alkoxyalkyl-substituierte Benzimidazole, ihre Herstellung und ihre Verwendung als Mittel gegen parasitäre Protozoen
DE10131149A1 (de) * 2001-06-28 2003-01-16 Bayer Ag Substituierte Benzinmidazole zur Bekämpfung von Endoparasiten
EP2335700A1 (en) * 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
US7098231B2 (en) * 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) * 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
AR045979A1 (es) * 2003-04-28 2005-11-23 Astrazeneca Ab Amidas heterociclicas
SE0302572D0 (sv) * 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302573D0 (sv) 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302571D0 (sv) * 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
SE0302570D0 (sv) * 2003-09-26 2003-09-26 Astrazeneca Ab Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof
WO2005037743A1 (en) * 2003-10-14 2005-04-28 E.I. Dupont De Nemours And Company Process for the preparation of 1,1,1,3,3-pentafluoropropane and 1,1,1,2,3-pentafluoropropane
DK1718608T3 (da) * 2004-02-20 2013-10-14 Boehringer Ingelheim Int Virale polymeraseinhibitorer
DE102004042958A1 (de) * 2004-09-02 2006-03-09 Bayer Healthcare Ag Neue antiparasitäre Kombination von Wirkstoffen
RU2374234C2 (ru) 2004-09-24 2009-11-27 Астразенека Аб Бензимидазольные производные, содержащие их композиции, их получение и применение
WO2006038871A1 (en) * 2004-10-08 2006-04-13 Astrazeneca Ab New hydroxymethylbenzothiazoles amides
SE0403117D0 (sv) * 2004-12-21 2004-12-21 Astrazeneca Ab New compounds 1
SE0403118D0 (sv) * 2004-12-21 2004-12-21 Astrazeneca Ab New compounds 2
SE0403171D0 (sv) * 2004-12-23 2004-12-23 Astrazeneca Ab New compounds
DE102005000746A1 (de) * 2005-01-05 2006-07-13 Bayer Healthcare Ag Bekämpfung der Histomoniasis
US8076365B2 (en) * 2005-08-12 2011-12-13 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
TW200745049A (en) 2006-03-23 2007-12-16 Astrazeneca Ab New crystalline forms
TW200808769A (en) 2006-04-18 2008-02-16 Astrazeneca Ab Therapeutic compounds
EP2416663A2 (en) 2009-03-18 2012-02-15 Martin Benedict George Donnelly Parasiticidal formulation
DE102009038950A1 (de) 2009-08-26 2011-03-03 Bayer Animal Health Gmbh Neue antiparasitäre Kombination von Wirkstoffen
US20110086853A1 (en) * 2009-10-08 2011-04-14 William Brown Therapeutic Compounds
US20110144216A1 (en) * 2009-12-16 2011-06-16 Honeywell International Inc. Compositions and uses of cis-1,1,1,4,4,4-hexafluoro-2-butene
CN105237480B (zh) * 2015-08-14 2017-12-05 三峡大学 一种2‑三氟甲基苯并咪唑化合物及其制备方法
EP3740466B1 (en) * 2018-01-17 2024-03-06 Migal Galilee Research Institute Ltd. New methionine metabolic pathway inhibitors

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3271249A (en) * 1963-06-24 1966-09-06 S B Penick & Co Inc Dihalobenzimidazoles for poultry disease treatment
GB1170737A (en) * 1964-05-27 1969-11-12 Fisons Pest Control Ltd Substituted Benzimadazoles and their use as Acaricides
GB1104936A (en) * 1964-05-27 1968-03-06 Fisons Pest Control Ltd Substituted benzimidazole-(1)-carboxylates
FR1439128A (fr) * 1965-04-02 1966-05-20 Chimetron Sulfonylbenzimidazolylcétones
FR1476531A (fr) * 1965-04-26 1967-04-14 Chimetron Sarl Nouvelles cétones halogénées dérivées du benzimidazole
GB1163711A (en) * 1966-01-13 1969-09-10 Fisons Pest Control Ltd Substituted Benzimidazoles and Biocidally-Active Compositions
GB1213796A (en) * 1967-04-14 1970-11-25 Shell Int Research 0-substituted-2-haloalkyl-benzimidazoles and -imidazopyridines, and their use as pesticides
NL7013343A (ko) * 1969-09-26 1971-03-30
DE2119518A1 (de) * 1971-04-22 1972-10-26 Farbenfabriken Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von N-substituiertenN-Chlormethylcarbamidsäureestern und -thiolestern
US3738994A (en) * 1971-08-13 1973-06-12 Merck & Co Inc 2-cyano-polyhalobenzimidazoles
ZA751024B (en) * 1974-03-11 1976-01-28 Lilly Co Eli Control of animal parasites with benzimidazoles
DE2736448A1 (de) * 1976-08-25 1978-03-02 Fisons Ltd Substituierte benzimidazole, ihre herstellung und verwendung
FR2521141A1 (fr) * 1982-02-09 1983-08-12 Rhone Poulenc Agrochimie Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides
FR2559150B1 (fr) * 1984-02-06 1986-06-27 Rhone Poulenc Agrochimie Nouveaux derives du cyano-2 benzimidazole, leur preparation et leur utilisation comme fongicides
US4859684A (en) * 1986-09-15 1989-08-22 Janssen Pharmaceutica N.V. (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders
NO874194L (no) * 1986-11-07 1988-05-09 Pfizer Ltd Fremgangsmaate ved fremstilling av dihydro-pyridinderivater

Also Published As

Publication number Publication date
AU670317B2 (en) 1996-07-11
ES2154641T3 (es) 2001-04-16
GR3035574T3 (en) 2001-06-29
DK0597304T3 (da) 2001-01-22
DE59310137D1 (de) 2001-02-15
EP0597304B1 (de) 2001-01-10
US5482956A (en) 1996-01-09
KR100278207B1 (ko) 2001-01-15
AU4873193A (en) 1994-05-19
TW264388B (ko) 1995-12-01
JPH06219946A (ja) 1994-08-09
EP0597304A1 (de) 1994-05-18
DE4237617A1 (de) 1994-05-11

Similar Documents

Publication Publication Date Title
KR940010903A (ko) 치환된 벤즈이미다졸의 용도
ES2191048T3 (es) Derivados de oxazolidinona y compuestos farmaceuticos que los contienen.
GT199800207A (es) Nuevos derivados de la eritromicina.
ES2193391T3 (es) Antagonistas muscarinicos.
BG106621A (en) Non-aqueous or hardly aqueous suspension concentrates of active substance combinations used for plant protection
NO933482D0 (no) N-sulfonyl-2-oksoindol-derivater som har affinitet for vasopressin- og/eller ocytocin-reseptorer
GT199800021A (es) Utilizacion de antagonistas de los receptores de canabinoides centrales para la preparacion de medicamentos.
ECSP045159A (es) "antagonistas nk1"
ES2172585T3 (es) Derivado de benzoimidazol.
BR9104533A (pt) Composicao antimicrobiana,derivados,processo para sua preparacao,medicamentos,composicoes pesticidas,utilizacao de derivados,processos para o combate de pragas e para a preparacao de composicoes
EA200200417A1 (ru) Фармацевтически активные производные сульфонамида
KR960704868A (ko) 환상 뎁시펩티드 화합물 (Cyclodepsipeptide Compound)
GT199800163A (es) Derivados de 9-amino-3-ceto eritromicina.
ATE369187T1 (de) Stabilisierung kosmetischer oder dermatologischer zubereitungen, welche repellent-wirkstoffe enthalten
ES2039246T3 (es) Composiciones repelentes de mosquitos.
SE8700113L (sv) Pesticid o/w-emulsion
ES2078297T3 (es) Piridazinaminas antipicornaviricas.
DE50012930D1 (de) Emulgatorfreie feindisperse systeme vom typ wasser-in-öl
BR0213418A (pt) Misturas de inversão para dispersões de polìmeros com melhor compatibilidade com o meio ambiente
BR0211729A (pt) Compostos, composições farmacêuticas, processo para fabricar compostos, uso de um ou mais compostos, e, processo para fabricar composições farmacêuticas
BR9915742A (pt) Preparados de limpeza contendo agentes tensoativos formadores de vesìcula à base de água, processo para sua preparação, assim como seu emprego
AR005532A1 (es) Compuestos de dihalopropeno, las composiciones insecticidas/acaricidas que los contienen y los intermediarios de sintesis de dichos compuestos
PE20011020A1 (es) Composiciones para tratamiento capilar que contienen tensioactivos anionicos y cationicos
ATE214939T1 (de) Behandlung von neurologischen zuständen durch eine interleukin-i-inhibierende verbindung
KR950704462A (ko) 고 친수성 및 고 소수성 비이온계 계면활성제의 혼합물을 함유하는 세정 조성물(cleaning compositions with combined highly hydrophilic and highly hydrophobic nonionic surfactants)

Legal Events

Date Code Title Description
A201 Request for examination
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20091009

Year of fee payment: 10

LAPS Lapse due to unpaid annual fee