GT199800163A - Derivados de 9-amino-3-ceto eritromicina. - Google Patents

Derivados de 9-amino-3-ceto eritromicina.

Info

Publication number
GT199800163A
GT199800163A GT199800163A GT199800163A GT199800163A GT 199800163 A GT199800163 A GT 199800163A GT 199800163 A GT199800163 A GT 199800163A GT 199800163 A GT199800163 A GT 199800163A GT 199800163 A GT199800163 A GT 199800163A
Authority
GT
Guatemala
Prior art keywords
compounds
derivatives
amino
erythromycin
keto
Prior art date
Application number
GT199800163A
Other languages
English (en)
Inventor
Yong-Jin Wu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199800163A publication Critical patent/GT199800163A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

ESTA INVENCION SE REFIERE A NUEVOS DERIVADOS DE 9AMINO3CETO11,12CARBAZATO O CARBAMATO DE 60METILERITROMICINA A. LOS COMPUESTOS DE ESTA INVENCION SON UTILES COMO AGENTES ANTIBIOTICOS EN MAMIFEROS, INCLUYENDO EL SER HUMANO, ASI COMO EN PECES Y AVES. ESTOS COMPUESTOS TIENEN LA ESTRUTURA QUIMICA I, EN LA QUE R1, R2, R3, R4 & X ; SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE. LOS COMPUESTOS DE FORMULA I, Y LAS SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS ("EN LO SUCESIVO LOS COMPUESTOS ACTIVOS"), PUEDEN ADMINISTRARSE MEDIANTE LA RUTA ORAL , PARENTERAL, TOPICA O RECTAL, EN EL TRATAMIENTO O PREVENCION DE INFECCIONES BACTERIANAS O PRODUCIDAS POR PROTOZOOS.
GT199800163A 1997-10-29 1998-10-23 Derivados de 9-amino-3-ceto eritromicina. GT199800163A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6367697P 1997-10-29 1997-10-29

Publications (1)

Publication Number Publication Date
GT199800163A true GT199800163A (es) 2000-04-15

Family

ID=22050768

Family Applications (1)

Application Number Title Priority Date Filing Date
GT199800163A GT199800163A (es) 1997-10-29 1998-10-23 Derivados de 9-amino-3-ceto eritromicina.

Country Status (13)

Country Link
US (1) US6159945A (es)
AP (1) AP9801378A0 (es)
AR (1) AR017177A1 (es)
AU (1) AU9277698A (es)
CO (1) CO4810375A1 (es)
GT (1) GT199800163A (es)
HN (1) HN1998000159A (es)
HR (1) HRP980571A2 (es)
MA (1) MA26558A1 (es)
PA (1) PA8461701A1 (es)
PE (1) PE122499A1 (es)
TN (1) TNSN98194A1 (es)
WO (1) WO1999021866A1 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6710033B1 (en) 1996-08-14 2004-03-23 Vanderbilt University Methods and treatment of multiple sclerosis
US6890526B2 (en) 1997-05-06 2005-05-10 Vanderbilt University Methods and reagents for the treatment of multiple sclerosis
AP9801420A0 (en) * 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
AU3439899A (en) 1998-06-03 1999-12-20 Pfizer Products Inc. Tricyclic 3-keto derivatives of 6-o-methylerythromycin
ES2273964T3 (es) * 1998-12-10 2007-05-16 Pfizer Products Inc. Antibioticos de carbamato y carbazato cetolida.
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
KR20020002380A (ko) 1999-01-27 2002-01-09 실버스타인 아써 에이. 케톨라이드 항생물질
KR20020016799A (ko) * 1999-05-24 2002-03-06 데이비드 존 우드 13-메틸-에리트로마이신 유도체
ID27331A (id) * 1999-09-29 2001-03-29 Pfizer Prod Inc Pembuatan antibiotik-antibiotik ketolida karbamat
US6498146B1 (en) * 1999-10-28 2002-12-24 Pfizer Inc Erythromycin derivatives
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
US20020115621A1 (en) * 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
US20070003508A1 (en) 2005-07-01 2007-01-04 Wooley Richard E Methods and compositions for promoting wound healing
US20040151765A1 (en) * 2001-09-18 2004-08-05 Ritchie Branson W. Methods and compositions for wound management
US20040208842A1 (en) * 2001-09-18 2004-10-21 Ritchie Branson W. Antimicrobial cleansing compositions and methods of use
CA2529817C (en) 2003-03-10 2013-02-12 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
WO2005091967A2 (en) * 2004-03-03 2005-10-06 University Of Georgia Research Foundation, Inc. Methods and compositions for ophthalmic treatment of fungal and bacterial infections
UA85937C2 (uk) 2004-12-21 2009-03-10 Пфайзер Продактс Інк. Макроліди
EP2214484A4 (en) 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS
US9072759B2 (en) 2008-10-24 2015-07-07 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
RU2650883C2 (ru) 2010-03-22 2018-04-18 Семпра Фармасьютикалз, Инк. Кристаллические формы макролида и их применение
CN102917708B (zh) 2010-05-20 2015-11-25 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
KR20180110181A (ko) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
IN2014DN08939A (es) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
US9861616B2 (en) 2013-03-14 2018-01-09 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
WO2014145210A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
EP2988597B1 (en) 2013-04-04 2022-06-08 President and Fellows of Harvard College Macrolides and methods of their preparation and use
CA2963815A1 (en) 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
EP3273969A4 (en) 2015-03-25 2018-11-21 President and Fellows of Harvard College Macrolides with modified desosamine sugars and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US6060234A (en) * 1991-01-17 2000-05-09 Abbott Laboratories Polyketide derivatives and recombinant methods for making same
DE69301916T2 (de) * 1992-04-22 1996-08-08 Taisho Pharmaceutical Co., Ltd., Tokio/Tokyo 5-0-desosaminylerythronolid a derivate
WO1998051696A1 (en) * 1997-05-09 1998-11-19 Pfizer Products Inc. Erythromycin derivatives
CZ9904388A3 (cs) * 1997-06-11 2002-10-16 Pfizer Products Inc. 9-Oximové deriváty erythromycinu

Also Published As

Publication number Publication date
MA26558A1 (fr) 2004-12-20
US6159945A (en) 2000-12-12
HN1998000159A (es) 1999-02-09
PE122499A1 (es) 1999-12-02
AU9277698A (en) 1999-05-17
AP9801378A0 (en) 2000-04-29
PA8461701A1 (es) 2000-05-24
AR017177A1 (es) 2001-08-22
CO4810375A1 (es) 1999-06-30
WO1999021866A1 (en) 1999-05-06
HRP980571A2 (en) 1999-08-31
TNSN98194A1 (fr) 2005-03-15

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