KR920703067A - 말초 신경질환 및 뇌질환 치료용 L-α-글리세로포르포릴-D-미오-이노시톨 - Google Patents
말초 신경질환 및 뇌질환 치료용 L-α-글리세로포르포릴-D-미오-이노시톨Info
- Publication number
- KR920703067A KR920703067A KR1019920700927A KR920700927A KR920703067A KR 920703067 A KR920703067 A KR 920703067A KR 1019920700927 A KR1019920700927 A KR 1019920700927A KR 920700927 A KR920700927 A KR 920700927A KR 920703067 A KR920703067 A KR 920703067A
- Authority
- KR
- South Korea
- Prior art keywords
- myo
- inositol
- glycerophosphoryl
- pharmaceutical composition
- peripheral neurological
- Prior art date
Links
- 208000014644 Brain disease Diseases 0.000 title claims description 5
- 208000012902 Nervous system disease Diseases 0.000 title claims description 5
- 208000025966 Neurological disease Diseases 0.000 title claims description 5
- 230000002093 peripheral effect Effects 0.000 title claims description 5
- 230000000926 neurological effect Effects 0.000 title description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 229910052783 alkali metal Inorganic materials 0.000 claims 4
- 150000001340 alkali metals Chemical class 0.000 claims 4
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims 4
- -1 alkaline earth metal salt Chemical class 0.000 claims 3
- 230000001988 toxicity Effects 0.000 claims 3
- 231100000419 toxicity Toxicity 0.000 claims 3
- 208000021959 Abnormal metabolism Diseases 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 159000000007 calcium salts Chemical class 0.000 claims 2
- 230000006371 metabolic abnormality Effects 0.000 claims 2
- 230000001594 aberrant effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000004060 metabolic process Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
내용 없음
Description
말초 신경질환 및 뇌질환 치료용 L-α-글리세로포스포릴-D-미오-이노시톨
[도면의 간단한 설명]
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (10)
- 활성 성분으로서 L-α-글리세로포스포릴-D-미오-이노시톨을 그 자체로서나 또는 그의 알칼리 금속 또는 알칼리-토금속염으로서 함유한, 이상대사 또는 독성 유래의 말초 신경질환 및 기질성 및 기능성 유래의 뇌질환 치료용의 제약 조성물.
- 제1항에 있어서, 활성성분으로서 L-α-글리세로포스포릴-D-미오-이노시톨을 칼슘염으로서 함유하는 제약 조성물.
- 제1항 또는 제2항에 있어서, 경구 투여용의 제약 조성물.
- 제1항 또는 재2항에 있어서, 비경구 투여용의 제약 조성물.
- 제1항 내지 제4항 중 어느 한 항에 있어서, 1회 투여당 L-α-글리세로포스포릴-D-미오-이노시톨을 그 자체로서나 또는 알칼리 금속 또는 알칼리-토금속염으로서 5 내지 500mg을 함유하는 제약 조성물.
- 제5항에 있어서, L-α-글리세로포스포릴-D-미오-이노시톨을 그의 칼슘염으로서 함유하는 제약 조성물.
- 이상대사 또는 독성 유래의 말초 신경질환 및 기질성 및 기능성 유래의 뇌질환 치료용 제약 조성물의 제조를 위한 L-α-글리세로포스포릴-D-미오-이노시톨 및 그의 알칼리 금속 또는 알칼리-토금속염의 용도.
- 이상대사 또는 독성 유래의 말초 신경질환 및 기질성 및 기능성 유래의 뇌질환 치료용 제약 조성물의 제조를 위한 L-α-글리세로포스포릴-D-미오-이노시톨 칼슘염의 용도.
- 알칼리 금속 또는 알칼리 -토금속염과의 L-α-글리세로포스포릴-D-미오-이노시톨염.
- L-α-글리세로포스포릴-D-미오-이노시톨 칼슘염.※ 참고사항:최초출원 내용에 의하여 공개되는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22173A IT1239474B (it) | 1989-10-27 | 1989-10-27 | Composizioni farmaceutiche a base di l-alfa-glicerofosforil-d-myo- inositolo o suoi sali alcalini o alcalino-terrosi per la terapia delleneuropatie periferiche di origine dismetabolica o tossica, e delle cerebropatie su base organica e funzionale |
IT22173A/89 | 1989-10-27 | ||
PCT/EP1990/001757 WO1991006301A1 (en) | 1989-10-27 | 1990-10-17 | L-alpha-glycerophosphoryl-d-myo-inositol for the treatment of peripheral neuropathies and of cerebropathies |
Publications (2)
Publication Number | Publication Date |
---|---|
KR920703067A true KR920703067A (ko) | 1992-12-17 |
KR0176978B1 KR0176978B1 (ko) | 1999-03-20 |
Family
ID=11192582
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019920700927A KR0176978B1 (ko) | 1989-10-27 | 1990-10-17 | 말초 신경질환 및 뇌질환 치료용 L-α-글리세로포스포릴-D-미오-이노시톨 |
Country Status (14)
Country | Link |
---|---|
US (1) | US5281586A (ko) |
EP (1) | EP0497906B1 (ko) |
JP (1) | JP3037749B2 (ko) |
KR (1) | KR0176978B1 (ko) |
AT (1) | ATE100713T1 (ko) |
AU (1) | AU645533B2 (ko) |
CA (1) | CA2067755A1 (ko) |
DE (1) | DE69006360T2 (ko) |
DK (1) | DK0497906T3 (ko) |
ES (1) | ES2062570T3 (ko) |
HU (2) | HU210767B (ko) |
IT (1) | IT1239474B (ko) |
NO (1) | NO179009C (ko) |
WO (1) | WO1991006301A1 (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1247093B (it) * | 1991-01-22 | 1994-12-12 | Flarer S R L Ora Castellini S | Derivati salini del gliceril fosforil mioinositolo ad attivita' terapeutica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
IT1265647B1 (it) * | 1992-11-18 | 1996-11-22 | Farmin Srl | Composizione farmaceutiche topiche per le allergie respiratorie |
GB9801899D0 (en) * | 1998-01-29 | 1998-03-25 | Univ London | Neurotrophic properties of ipgs analogues |
CA2427352C (en) * | 2000-11-07 | 2010-10-12 | I.R.B. Istituto Di Ricerche Biotecnologiche S.R.L. | Glycerophosphoinositol derivatives as modulators of cytosolic phospholipase |
JP5670858B2 (ja) * | 2011-10-14 | 2015-02-18 | イ.エルレ.ビ.イスティトゥト ディ リチェルケ ビオテクノロジケ ソチエタ ペル アツィオニ | サイトゾルのホスホリパーゼのモジュレーターとしてのグリセロホスホイノシトール誘導体 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3239817A1 (de) * | 1982-07-06 | 1984-01-12 | Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen | Neue glycerinderivate zur synthese von phospholipiden |
-
1989
- 1989-10-27 IT IT22173A patent/IT1239474B/it active IP Right Grant
-
1990
- 1990-10-17 HU HU9201267A patent/HU210767B/hu not_active IP Right Cessation
- 1990-10-17 CA CA002067755A patent/CA2067755A1/en not_active Abandoned
- 1990-10-17 KR KR1019920700927A patent/KR0176978B1/ko not_active IP Right Cessation
- 1990-10-17 AU AU68848/91A patent/AU645533B2/en not_active Ceased
- 1990-10-17 WO PCT/EP1990/001757 patent/WO1991006301A1/en active IP Right Grant
- 1990-10-17 JP JP03500082A patent/JP3037749B2/ja not_active Expired - Lifetime
- 1990-10-17 DK DK90917445.0T patent/DK0497906T3/da active
- 1990-10-17 EP EP90917445A patent/EP0497906B1/en not_active Expired - Lifetime
- 1990-10-17 AT AT90917445T patent/ATE100713T1/de not_active IP Right Cessation
- 1990-10-17 DE DE69006360T patent/DE69006360T2/de not_active Expired - Fee Related
- 1990-10-17 ES ES90917445T patent/ES2062570T3/es not_active Expired - Lifetime
- 1990-10-17 US US07/836,337 patent/US5281586A/en not_active Expired - Fee Related
-
1992
- 1992-04-14 HU HU9201267A patent/HU9201267D0/hu unknown
- 1992-04-21 NO NO921525A patent/NO179009C/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE100713T1 (de) | 1994-02-15 |
IT8922173A0 (it) | 1989-10-27 |
DK0497906T3 (da) | 1994-03-21 |
DE69006360T2 (de) | 1994-05-19 |
AU645533B2 (en) | 1994-01-20 |
HU9201267D0 (en) | 1992-07-28 |
CA2067755A1 (en) | 1991-04-28 |
ES2062570T3 (es) | 1994-12-16 |
EP0497906A1 (en) | 1992-08-12 |
NO921525L (no) | 1992-04-21 |
NO921525D0 (no) | 1992-04-21 |
NO179009B (no) | 1996-04-09 |
KR0176978B1 (ko) | 1999-03-20 |
DE69006360D1 (de) | 1994-03-10 |
JPH05502861A (ja) | 1993-05-20 |
JP3037749B2 (ja) | 2000-05-08 |
AU6884891A (en) | 1991-05-31 |
IT8922173A1 (it) | 1991-04-27 |
HU210767B (en) | 1995-07-28 |
NO179009C (no) | 1996-07-17 |
EP0497906B1 (en) | 1994-01-26 |
HUT61667A (en) | 1993-03-01 |
WO1991006301A1 (en) | 1991-05-16 |
IT1239474B (it) | 1993-11-02 |
US5281586A (en) | 1994-01-25 |
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Legal Events
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A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |