KR920021161A - 치료학적 용도의 비-공극성 콜라겐 시이트, 이를 제조하는 방법 및 장치 - Google Patents

치료학적 용도의 비-공극성 콜라겐 시이트, 이를 제조하는 방법 및 장치 Download PDF

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Publication number
KR920021161A
KR920021161A KR1019920005043A KR920005043A KR920021161A KR 920021161 A KR920021161 A KR 920021161A KR 1019920005043 A KR1019920005043 A KR 1019920005043A KR 920005043 A KR920005043 A KR 920005043A KR 920021161 A KR920021161 A KR 920021161A
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South Korea
Prior art keywords
collagen
zone
collagen gel
less
making
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KR1019920005043A
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English (en)
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KR100229304B1 (ko
Inventor
푸르랜 디에고
본판티 지오반니
스카빠티치 쥬세빼
Original Assignee
푸르랜 디에고
유로리써치 에스.알.엘.
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Application filed by 푸르랜 디에고, 유로리써치 에스.알.엘. filed Critical 푸르랜 디에고
Publication of KR920021161A publication Critical patent/KR920021161A/ko
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Publication of KR100229304B1 publication Critical patent/KR100229304B1/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18—Manufacture of films or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/043—Proteins; Polypeptides; Degradation products thereof
    • A61L31/044—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D19/00—Degasification of liquids
    • B01D19/0031—Degasification of liquids by filtration
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2389/00—Characterised by the use of proteins; Derivatives thereof
    • C08J2389/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08J2389/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin

Abstract

내용 없음.

Description

치료학적 용도의 비-공극성 콜라겐 시이트, 이를 제조하는 방법 및 장치
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 콜라겐 시이트 제조시 건조공정중 사용되는 오븐의 구조를 나타낸다.

Claims (4)

  1. H2O함량이 20중량%이하 이고, 0.02내지 2mm두께의 시이트 형태로 존재하며, 치밀한 투명 구조이고, 중량의 최대 15배 이하까지 생물학적 체액을 흡수할 수 있으며, 천연 콜라겐 분해 산물을 함유하지 않는, 상해 및 화상의 치료학적 처리에 적합한 타입 I 콜라겐 겔.
  2. 20 내지 60mmHg의 진공하에 여액내로의 기포 혼입을 방지하는 장치가 제공된, 통로 크기가 0.1mm이하인 필터의 표면을 통해 pH2.5 내지 3.5의 희석된 수성 콜라겐 겔을 여과시킨 후, 트레이내에 함유된 액체 겔을 조절된 온도 및 상대습도 조건하에 질소 스트림으로 건조시킴을 특징으로 하여, 상기 겔로부터 제1항에 청구된 바와 같은 콜라겐 겔 시이트를 제조하는 방법.
  3. 연속적 액체 필름으로서 여액을 운반하기 위한, 메쉬 크기 0.1mm이하의 금속 메쉬로 구성되고, 필터 메쉬 하부 영역에 일단의 평행 플레이트가 제공된, 제2항에 따라서 콜라겐 겔을 여과하기에 적합한 장치.
  4. 트레이내에 함유된 액체를 건조시키는 영역, 건조 영역, 냉각 영역 및 가열 영역의 밀폐된 회로내에서 질소 스트림을 순환시키는 수단 및 건조 영역내로 유입된 기체 스트림의 상대습도를 조절하기 위해 냉각 및 가열 온도를 조절하기 위한 수단으로 이루어짐을 특징으로 하는, 제2항에 따라서 콜라겐 겔을 건조시키기에 적합한 장치.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019920005043A 1991-05-23 1992-03-27 치료학적 용도의 비-공극성 콜라겐 시이트, 이를 제조하는 방법 및 장치 KR100229304B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT91A001423 1991-05-23
ITMI911423A IT1249315B (it) 1991-05-23 1991-05-23 Lamina di collageno non poroso per uso terapeutico, metodo ed apparecchiature per ottenerlo

Publications (2)

Publication Number Publication Date
KR920021161A true KR920021161A (ko) 1992-12-18
KR100229304B1 KR100229304B1 (ko) 1999-11-01

Family

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Family Applications (1)

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KR1019920005043A KR100229304B1 (ko) 1991-05-23 1992-03-27 치료학적 용도의 비-공극성 콜라겐 시이트, 이를 제조하는 방법 및 장치

Country Status (8)

Country Link
EP (1) EP0514691B1 (ko)
JP (1) JP3423330B2 (ko)
KR (1) KR100229304B1 (ko)
CN (1) CN1066790A (ko)
AT (1) ATE132517T1 (ko)
CA (1) CA2064993C (ko)
DE (1) DE69207263T2 (ko)
IT (1) IT1249315B (ko)

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US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
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US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
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US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
JP5701468B2 (ja) * 2001-10-12 2015-04-15 モノソル・アールエックス・エルエルシー 自己凝集しない均一な異種性を有する薄膜、その生成方法、およびそれから製造した薬物送達系
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JP4621563B2 (ja) * 2005-08-26 2011-01-26 新田ゼラチン株式会社 皮膚用保水シート
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KR20230137362A (ko) 2016-05-05 2023-10-04 어퀘스티브 테라퓨틱스, 아이엔씨. 강화된 전달 에프네프린 조성물
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Also Published As

Publication number Publication date
JP3423330B2 (ja) 2003-07-07
KR100229304B1 (ko) 1999-11-01
ATE132517T1 (de) 1996-01-15
EP0514691B1 (en) 1996-01-03
JPH05117162A (ja) 1993-05-14
CA2064993A1 (en) 1992-11-24
EP0514691A2 (en) 1992-11-25
CN1066790A (zh) 1992-12-09
ITMI911423A1 (it) 1992-11-23
IT1249315B (it) 1995-02-22
EP0514691A3 (en) 1993-03-31
ITMI911423A0 (it) 1991-05-23
DE69207263D1 (de) 1996-02-15
DE69207263T2 (de) 1996-05-15
CA2064993C (en) 2005-01-18

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