KR920009795A - 4-치환-5-(트리플루오로 메틸)피롤-3-카보니트릴 화합물의 제조방법 - Google Patents

4-치환-5-(트리플루오로 메틸)피롤-3-카보니트릴 화합물의 제조방법 Download PDF

Info

Publication number
KR920009795A
KR920009795A KR1019910020352A KR910020352A KR920009795A KR 920009795 A KR920009795 A KR 920009795A KR 1019910020352 A KR1019910020352 A KR 1019910020352A KR 910020352 A KR910020352 A KR 910020352A KR 920009795 A KR920009795 A KR 920009795A
Authority
KR
South Korea
Prior art keywords
alkyl
substituted
optionally substituted
halogen atoms
group
Prior art date
Application number
KR1019910020352A
Other languages
English (en)
Other versions
KR100204109B1 (ko
Inventor
케임즈와란 벤카타라만
Original Assignee
알퐁스 아아르 노에
아메리칸 사이아나밋드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 알퐁스 아아르 노에, 아메리칸 사이아나밋드 캄파니 filed Critical 알퐁스 아아르 노에
Publication of KR920009795A publication Critical patent/KR920009795A/ko
Application granted granted Critical
Publication of KR100204109B1 publication Critical patent/KR100204109B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

4-치환-5-(트리플루오로 메틸)피롤-3-카보니트릴 화합물의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

  1. 적어도 약 1몰 당량의 염기 준재하에서 일반식Ⅱ:
    (식에서 W는 CF3, C1-C4알킬, C1-C4알콕시, CH, NO2또는 한개 내지 세개의 할로겐원자로 임의 치환된 페닐; α-또는 β-나프틸; 또는 CF3또는 한개 내지 세개의 할로겐 원자로 임의 치환된 2-, 3- 또는 4- 피리딜이다)를 갖는 옥심 화합물을, 일반식 Ⅲ:
    (식에서 Y는 수소 또는 W이고, X는 C1, Br 또는 I는 이다)을 갖는 β-할로-α, β-불포화 니트릴 화합물 및 이의 시스-및 트랜스-이성질체 적어도 약 1몰 당량과 반응시켜 4-치환-5-(트리플루오로메틸) 피롤-3-카보니트릴 화합물을 형성함으로 구성되는 일반식.
    (식에서 Y 및 W는 전술한 바와 같다)을 특징으로 하는 4-치환-5-(트리플루오로메틸) 피롤-3-카보니트릴 화합물의 제조방법.
  2. 제1항에 있어서, β-할로-α, β-불포화니트릴은 1내지 4몰당량의 양으로 존재하는 방법.
  3. 제2항에 있어서, 염기는 1 내지 4몰당량의 양으로 존재하는 방법.
  4. 제1항에 있어서, 염기는 알킬리 금속 C1-C6알콕시드, 알킬리금속 수소화물 및 알칼리금속 수산화물로 구성되는 군으로부터 선택되는 방법.
  5. 제4항에 있어서, 용해는 에테르, 디옥산, 톨루엔, 테트라하이드로푸란 및 C1내지 C6알코올로 구성되는 군으로부터 선택되는 방법.
  6. 제1항에 있어서, 반응 혼합물의 온도는 -5℃ 내지 35℃인 방법.
  7. 제1항에 있어서, W는 CF3, C1내지 C4알킬, C1내지 C4알콕시, CN, NO2, 및 한개 내지 세개의 할로겐원자로 구성되는 군으로부터 선택되는 치환체로 임의 치환된 페닐인 방법.
  8. 제7항에 있어서, X는 C1인 방법.
  9. 제7항에 있어서, X는 Br인 방법.
    ※참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910020352A 1990-11-16 1991-11-15 4-치환-5-(트리플루오로메틸)피롤-3-카보니트릴 화합물의 제조방법 KR100204109B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/614,541 US5106985A (en) 1990-11-16 1990-11-16 Process for the preparation of insecticidal, nematicidal and acaricidal 4-substituted-5-(trifluoromethyl)pyrrole-3-carbonitrile compounds
US07/614,541 1990-11-16
US7/614,541 1990-11-16

Publications (2)

Publication Number Publication Date
KR920009795A true KR920009795A (ko) 1992-06-25
KR100204109B1 KR100204109B1 (ko) 1999-06-15

Family

ID=24461695

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910020352A KR100204109B1 (ko) 1990-11-16 1991-11-15 4-치환-5-(트리플루오로메틸)피롤-3-카보니트릴 화합물의 제조방법

Country Status (12)

Country Link
US (1) US5106985A (ko)
EP (1) EP0485716B1 (ko)
JP (1) JP3061668B2 (ko)
KR (1) KR100204109B1 (ko)
AT (1) ATE134614T1 (ko)
BR (1) BR9104950A (ko)
DE (1) DE69117438T2 (ko)
DK (1) DK0485716T3 (ko)
ES (1) ES2085939T3 (ko)
GR (1) GR3019143T3 (ko)
PT (1) PT99505B (ko)
SG (1) SG52315A1 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5229524A (en) * 1990-10-18 1993-07-20 American Cyanamid Company Bis-and tris (trifluoromethyl) arylpyrrole insecticidal and acaricidal agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929634A (en) * 1987-10-23 1990-05-29 American Cyanamid Company Method of and bait compositions for controlling mollusks
EP0358047A3 (en) * 1988-09-08 1991-05-29 American Cyanamid Company Method of controlling phytopathogenic fungi

Also Published As

Publication number Publication date
EP0485716B1 (en) 1996-02-28
DE69117438D1 (de) 1996-04-04
JP3061668B2 (ja) 2000-07-10
BR9104950A (pt) 1992-06-23
PT99505B (pt) 1999-04-30
DE69117438T2 (de) 1996-10-10
GR3019143T3 (en) 1996-05-31
EP0485716A1 (en) 1992-05-20
ATE134614T1 (de) 1996-03-15
KR100204109B1 (ko) 1999-06-15
US5106985A (en) 1992-04-21
SG52315A1 (en) 1998-09-28
DK0485716T3 (da) 1996-03-18
JPH04290867A (ja) 1992-10-15
ES2085939T3 (es) 1996-06-16
PT99505A (pt) 1992-09-30

Similar Documents

Publication Publication Date Title
KR860001104A (ko) 테트라히드로프탈이미드의 제조방법
KR950000836A (ko) 실라시클로헥산화합물, 그의 제조방법 및 이것을 함유하는 액정조성물
NZ512818A (en) Process for preparing anti-cancer quinazoline compounds
SE8704599D0 (sv) Teobrominderivat
ES467288A1 (es) Un procedimiento para la preparacion de nuevas n-(aminoal- cohil sustituido)-2-oxo-1-pirrolidinacetamidas.
BG96285A (bg) 1-арил-5-/субституирани алкилиденимино/пиразоли с пестицидна активност
DK380680A (da) Fremgangsmaade til fremstilling af substituerede oxirancarboxylsyrer
KR850001184A (ko) 1,5-벤조티아제핀 유도체의 제조방법
KR950000837A (ko) 실라시클로헥산화합물, 그의 제조방법 및 이것을 함유하는 액정조성물
KR850003719A (ko) 시아노피라졸 제초제에 대한 개량
KR850003394A (ko) 신규의 벤젠설포닐-락탐을 활성물질로서 포함하는 약학적 조성물과 그 제조방법
KR960017638A (ko) 옥사졸 아민 중간체를 통한 아릴피롤류 살충제의 제조방법
KR920009795A (ko) 4-치환-5-(트리플루오로 메틸)피롤-3-카보니트릴 화합물의 제조방법
ES8702324A1 (es) Procedimiento para preparar compuestos 2-(hidroxialquil) acrilicos
KR850001664A (ko) 2,6-비스-(플루오로알킬)테트라하이드로 피란과 피페리딘의 3,5-디카르복실릭 에시드에스테르로 구성된 제초제조성물과 그 제조방법
KR830007510A (ko) 심장질환 치료제의 제조방법
KR850001177A (ko) 페녹시 페닐 알칸 유도체의 제조방법
DK0832067T3 (da) Fremgangsmåde til omdannelse af 2,4-dichlorpyridiner til 2-aryloxy-4-chlorpyridiner
KR910007945A (ko) 알킬 메틸-3-카브알콕시에틸포스피네이트의 제조방법
KR920009833A (ko) 3-알콕시메틸 세파로스포린 유도체의 제조방법
EP0855383A3 (en) Anti-ferroelectric liquid crystal compounds
ES8500910A1 (es) Un procedimiento para la preparacion de 6-(fenil sustituido)-3(2h)-piridazinonas.
DK0694029T3 (da) Fremgangsmåde til fremstilling af forbindelser afledt af beta-alkoxy-acrylsyre
KR910007849A (ko) 치환된 페놀의 제조방법
KR840004720A (ko) 살충제 조성물 및 이의 제조방법

Legal Events

Date Code Title Description
A201 Request for examination
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
LAPS Lapse due to unpaid annual fee