KR920007637A - 종양 괴사 인자 생성 억제제, 이의 제조방법 및 이의 용도 - Google Patents

종양 괴사 인자 생성 억제제, 이의 제조방법 및 이의 용도 Download PDF

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Publication number
KR920007637A
KR920007637A KR1019910017935A KR910017935A KR920007637A KR 920007637 A KR920007637 A KR 920007637A KR 1019910017935 A KR1019910017935 A KR 1019910017935A KR 910017935 A KR910017935 A KR 910017935A KR 920007637 A KR920007637 A KR 920007637A
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KR
South Korea
Prior art keywords
lipopolysaccharide
inhibitor according
necrosis factor
tumor necrosis
macrophages
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KR1019910017935A
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English (en)
Inventor
에프. 샤데 울리히
Original Assignee
이젠브루크, 라피체
훽스트 아크티엔게젤샤프트
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Publication date
Application filed by 이젠브루크, 라피체, 훽스트 아크티엔게젤샤프트 filed Critical 이젠브루크, 라피체
Publication of KR920007637A publication Critical patent/KR920007637A/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

내용 없음

Description

종양 괴사 인자 생성 억제제, 이의 제조방법 및 이의 용도
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (9)

  1. 지질다당류-내성의 척추동물의 대식세포 또는 단핵식세포를 배약시켜 수득할 수 있는 종양 괴사 인자 생성 억제제.
  2. 제1항에 있어서, 지질다당류-내성의 마우스의 대식세포를 배양시켜 수득할 수 있는 억제제.
  3. 제1항에 있어서, 지질다당류-내성의 사람의 단핵식세포를 배양시켜 수득할 수 있는 억제제.
  4. 제1항 내지 제3항중 어느 한 항에 있어서, 분자량이 40,000 내지 80,000인 억제제.
  5. 지질다당류 존재하에 지질다당류-내성의 척추동물의 대식세포 또는 단핵 식세퐁를 배양시킴을 특징으로 하여 제1항 내지 제4항중 어느 한 항에 따른 억제제를 제조하는 방법.
  6. 제5항에 있어서, 살모넬라의 지질다당류를 배지 1㎖당 1 내지 100㎍의 농도를 사용하는 방법.
  7. 제6항에 있어서, 살모넬라의 지질다당류를 배지 1㎖당 5 내지 60㎍의 농도를 사용하는 방법.
  8. 제5항 내지 제 7항중 어느 한 항에 있어서, 대식세포 또는 단핵 식세포를 10시간 내지 1주일, 바람직하게는 15 내지 36시간 동안 배양시키는 방법.
  9. 종양 괴사 인자에 의한 질병의 치료 또는 예방용 약제 제조용으로서 사용하기 위한 제1항 내지 제4항중 어느 한 항에 따른 억제제의 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910017935A 1990-10-12 1991-10-11 종양 괴사 인자 생성 억제제, 이의 제조방법 및 이의 용도 KR920007637A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4032354.4 1990-10-12
DE4032354 1990-10-12

Publications (1)

Publication Number Publication Date
KR920007637A true KR920007637A (ko) 1992-05-27

Family

ID=6416122

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910017935A KR920007637A (ko) 1990-10-12 1991-10-11 종양 괴사 인자 생성 억제제, 이의 제조방법 및 이의 용도

Country Status (16)

Country Link
US (1) US5304634A (ko)
EP (1) EP0480389A1 (ko)
JP (1) JPH0578399A (ko)
KR (1) KR920007637A (ko)
CN (1) CN1060474A (ko)
AU (1) AU642772B2 (ko)
CA (1) CA2053347A1 (ko)
CS (1) CS309891A3 (ko)
FI (1) FI914776A (ko)
HU (1) HU209914B (ko)
IE (1) IE913605A1 (ko)
IL (1) IL99705A0 (ko)
NO (1) NO913995L (ko)
NZ (1) NZ240176A (ko)
PT (1) PT99195A (ko)
ZA (1) ZA918116B (ko)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101673440B1 (ko) 2015-06-29 2016-11-07 주식회사 영도트림아트 개구를 크게 하여 콘 셔틀을 위입 시키는 고속 세폭 직기
KR101673436B1 (ko) 2015-06-15 2016-11-07 주식회사 영도트림아트 콘 셔틀 고속 세폭 직기
KR102080549B1 (ko) 2020-01-03 2020-02-24 차현석 부드러운 북골직 테이프 제조방법 및 그 제조장치

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997042820A1 (en) 1996-05-16 1997-11-20 Duke University Tristetraprolin
US5669329A (en) * 1996-08-19 1997-09-23 Pets International, Ltd. Water bottle apparatus
US20020077276A1 (en) * 1999-04-27 2002-06-20 Fredeking Terry M. Compositions and methods for treating hemorrhagic virus infections and other disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL83878A (en) * 1987-09-13 1995-07-31 Yeda Res & Dev Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
GB8807803D0 (en) * 1988-03-31 1988-05-05 Glaxo Group Ltd Biochemical product
US5055447A (en) * 1988-07-28 1991-10-08 Genentech, Inc. Method and compositions for the treatment and prevention of septic shock
IL95031A (en) * 1989-07-18 2007-03-08 Amgen Inc A method of producing a recombinant human necrotic factor absorber

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101673436B1 (ko) 2015-06-15 2016-11-07 주식회사 영도트림아트 콘 셔틀 고속 세폭 직기
KR101673440B1 (ko) 2015-06-29 2016-11-07 주식회사 영도트림아트 개구를 크게 하여 콘 셔틀을 위입 시키는 고속 세폭 직기
KR102080549B1 (ko) 2020-01-03 2020-02-24 차현석 부드러운 북골직 테이프 제조방법 및 그 제조장치

Also Published As

Publication number Publication date
JPH0578399A (ja) 1993-03-30
NO913995D0 (no) 1991-10-11
FI914776A0 (fi) 1991-10-10
HU913210D0 (en) 1992-01-28
CN1060474A (zh) 1992-04-22
IE913605A1 (en) 1992-04-22
CA2053347A1 (en) 1992-04-13
AU642772B2 (en) 1993-10-28
US5304634A (en) 1994-04-19
ZA918116B (en) 1992-06-24
IL99705A0 (en) 1992-08-18
AU8577591A (en) 1992-04-16
PT99195A (pt) 1992-09-30
CS309891A3 (en) 1992-05-13
FI914776A (fi) 1992-04-13
NZ240176A (en) 1992-11-25
NO913995L (no) 1992-04-13
EP0480389A1 (de) 1992-04-15
HUT60750A (en) 1992-10-28
HU209914B (en) 1994-11-28

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