KR920002602A - 광학 활성이 있는 폴린산 및 그 염의 제조방법 - Google Patents
광학 활성이 있는 폴린산 및 그 염의 제조방법 Download PDFInfo
- Publication number
- KR920002602A KR920002602A KR1019900009942A KR900009942A KR920002602A KR 920002602 A KR920002602 A KR 920002602A KR 1019900009942 A KR1019900009942 A KR 1019900009942A KR 900009942 A KR900009942 A KR 900009942A KR 920002602 A KR920002602 A KR 920002602A
- Authority
- KR
- South Korea
- Prior art keywords
- calcium
- salts
- optically active
- preparing optically
- leucoborine
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (4)
- (6R,S)-5, 10-메테닐-테트라히드로폴산의 산염을 염화칼슘, 2수화물과 함께 가수분해 반응을 시킨 후, 생성된 반응액 중에서 직접 (6S)-류코보린, 칼슘을 제조하는 방법.
- 제1항에 있어서, 가수분해 반응을 pH6.5-6.9에서 실시함을 특징으로 하는 (6S)-류코보린, 칼슘의 제조방법.
- 제1항에 있어서, 염화칼슘, 2수화물을 2-15당량을 사용함을 특징으로 하는 (6S)-류코보린, 칼슘의 제조방법.
- 제1항에 있어서, 반응액을 30℃에서 알카리를 넣어 pH를 9.5-11로 조정하고, 15-20℃에서 (6S)-류코보린, 칼슘을 결정화됨을 특징으로 하는 (6S)-류코보린 칼슘의 제조방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019900009942A KR920006420B1 (ko) | 1990-07-02 | 1990-07-02 | 광학활성이 있는 류코보린칼슘염의 제조방법 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019900009942A KR920006420B1 (ko) | 1990-07-02 | 1990-07-02 | 광학활성이 있는 류코보린칼슘염의 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR920002602A true KR920002602A (ko) | 1992-02-28 |
| KR920006420B1 KR920006420B1 (ko) | 1992-08-06 |
Family
ID=19300781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019900009942A KR920006420B1 (ko) | 1990-07-02 | 1990-07-02 | 광학활성이 있는 류코보린칼슘염의 제조방법 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR920006420B1 (ko) |
-
1990
- 1990-07-02 KR KR1019900009942A patent/KR920006420B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR920006420B1 (ko) | 1992-08-06 |
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| E701 | Decision to grant or registration of patent right | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 20010703 Year of fee payment: 10 |
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| LAPS | Lapse due to unpaid annual fee |