KR910701823A - 프룩토사민의 측정 방법 - Google Patents

프룩토사민의 측정 방법

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Publication number
KR910701823A
KR910701823A KR1019910700931A KR910700931A KR910701823A KR 910701823 A KR910701823 A KR 910701823A KR 1019910700931 A KR1019910700931 A KR 1019910700931A KR 910700931 A KR910700931 A KR 910700931A KR 910701823 A KR910701823 A KR 910701823A
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KR
South Korea
Prior art keywords
general formula
carbon atoms
active oxygen
oxygen generating
detectable change
Prior art date
Application number
KR1019910700931A
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English (en)
Inventor
미씨오 하마
미찌요 나까야마
미쯔나오 다나까
Original Assignee
후지이 야쓰오
가부시끼사이샤 야트론
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 후지이 야쓰오, 가부시끼사이샤 야트론 filed Critical 후지이 야쓰오
Publication of KR910701823A publication Critical patent/KR910701823A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/904—Oxidation - reduction indicators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

내용 없음

Description

프룩토사민의 측정 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 당화 알부민 양과 흡광도와의 관계를 나타내는 그래프이다. 제2도는 본 발명의 방법과 종래의 HPLC 법과의 상관관계를 나타내는 그래프이다.

Claims (11)

  1. (a)수성액체 피검 시료와 활성 산소 생성물질을 접촉시키는 공정, (b)활성산소로부터 유도되는 과산화수소의 존재하에 검출가능한 변화를 일으키는 시약과 상기 공정(a)의 생성물을 접촉시키는 공정, 및 (c)상기 공정(b)의 검출가능한 변화를 검출하는 공정을 포함하는 것을 특징으로 하는, 수성액체중의 프룩토사민(fructosamine)을 측정하는 방법.
  2. 제1항에 있어서, 활성 산소 생성물질로서 하기 일반식(Ⅰ)로 표시되는 페나듐 화합물을 사용하는 방법:
    상기식에서, R1은 탄소수 1내지 4개의 저급 알킬기이며, R2는 수소원자, 탄소수 1내지 4개의 저급 알킬기 또는 탄소수 1내지 4개의 저급 알콕시기이고, X1은 음이온이다.
  3. 제1항에 있어서, 활성 산소 생성물질로서 하기 일반식(2)로 표시되는 비피리딘 화합물을 사용하는 방법:
    상기식에서, R3및 R4는 각각 독립적으로 탄소수 1내지 4개의 저급 알킬기이며, X2는 음이온이다.
  4. 제1항에 있어서, 활성 산소 생성물질로서 하기 일반식(3)으로 표시되는 1,4-형퀴논 화합물을 사용하는 방법:
    상기식에서, R5는 수소원자 또는 탄소수 1내지 4개의 저급 알킬기이며, B1및 B2는 각각 수소원자이거나, 또는 상기 일반식중의 2개의 탄소원자와 함께 벤젠환을 형성하는데 필요한 원자이다.
  5. 제1항에 있어서, 활성 산소 생성물질로서 하기 일반식(4)로 표시되는 1, 2-형퀴논 화합물을 사용하는 방법:
    상기식에서, B3및 B4는 각각 수소원자이거나, 또는 상기 일반식중의 2개의 탄소원자와 함께 벤젠환을 형성하거나, 또는 치환되거나 치환되지 않은 피리딘 환을 형성하는데 필요한 원자이며, B5및 B6은 상기 일반식중의 2개의 탄소원자와 함께 벤젠화를 형성하거나, 또는 치환되거나 치환되지 않은 피롤환을 형성하는데 필요한 원자이다.
  6. 제1항에 있어서, 활성 산소 생성물질로서 하기 일반식(5)로 표시되는 테트라 졸륨염을 사용하는 방법:
    상기식에서, Y는 할로겐화 페닐기, 치환되거나 치환되지 않은 티아졸릴기, 또는 일반식
    으로 표시되는 기이며, R6는 수소원자 또는 니트로기이고, R7및 R8은 각각 독립적으로 탄소수 1내지 4개의 저급 알킬기이며, X3및 X4는 각각 독립적으로 음이온이다.
  7. 제6항에 있어서, 상기 일반식(5)로 표시되는 테트라졸륨 염과 슈퍼옥시드 디스무타아제를 사용하는 방법.
  8. 제1항에 있어서, 수성액체 피검 시료가 생물학적 수성액체인 방법.
  9. 제1항에 있어서, 과산화 수소의 존재하에 검출가능한 변화를 일으키는 시약이 과산화 활성을 지닌 물질과, 과산화 활성 물질의 존재하에 착색 또는 변색하는 색소 전구체 또는 형광을 발생하는 물질로 이루어지는 방법.
  10. 제1항에 있어서, 활성 산소 생성물질, 및 과산화수소의 존재하에 검출가능한 변화를 일으키는 시약을 함유하는 계에 피검 액체를 첨가하고, 검출가능한 변화를 검출하는 것으로 이루어진 방법.
  11. 제1항에 있어서, 피검시료와 활성 산소 생성 물질을 접촉시켜 과산화수소를 유도시키고, 이어서 상기 과산화수소로부터 검출가능한 변화를 일으켜 상기 검출가능한 변화를 검출하는 것으로 이루어진 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019910700931A 1989-12-20 1990-12-19 프룩토사민의 측정 방법 KR910701823A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP330165/89 1989-12-20
JP1330165A JP2796150B2 (ja) 1989-12-20 1989-12-20 フルクトサミンの測定方法
PCT/JP1990/001653 WO1991009314A1 (fr) 1989-12-20 1990-12-19 Procede de detection de fructosamine

Publications (1)

Publication Number Publication Date
KR910701823A true KR910701823A (ko) 1992-08-12

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ID=18229546

Family Applications (1)

Application Number Title Priority Date Filing Date
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Country Status (8)

Country Link
US (1) US5312759A (ko)
EP (1) EP0463171B1 (ko)
JP (1) JP2796150B2 (ko)
KR (1) KR910701823A (ko)
AU (1) AU638524B2 (ko)
CA (1) CA2045665A1 (ko)
DE (1) DE69026611T2 (ko)
WO (1) WO1991009314A1 (ko)

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US7943385B2 (en) * 2006-07-25 2011-05-17 General Atomics Methods for assaying percentage of glycated hemoglobin
JP2009544315A (ja) * 2006-07-25 2009-12-17 ジェネラル アトミクス 糖化ヘモグロビンのパーセントを定量するための方法
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KR101789787B1 (ko) * 2016-08-17 2017-10-25 주식회사 바이오맥스 염료를 이용한 마이코플라즈마 검출방법

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Also Published As

Publication number Publication date
JPH03189561A (ja) 1991-08-19
WO1991009314A1 (fr) 1991-06-27
JP2796150B2 (ja) 1998-09-10
EP0463171B1 (en) 1996-04-17
EP0463171A4 (en) 1993-03-10
AU6906791A (en) 1991-07-18
EP0463171A1 (en) 1992-01-02
DE69026611T2 (de) 1996-08-14
AU638524B2 (en) 1993-07-01
DE69026611D1 (de) 1996-05-23
CA2045665A1 (en) 1991-06-21
US5312759A (en) 1994-05-17

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