KR910009637A - 비닐-gaba의 제조방법 - Google Patents

비닐-gaba의 제조방법 Download PDF

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Publication number
KR910009637A
KR910009637A KR1019900017806A KR900017806A KR910009637A KR 910009637 A KR910009637 A KR 910009637A KR 1019900017806 A KR1019900017806 A KR 1019900017806A KR 900017806 A KR900017806 A KR 900017806A KR 910009637 A KR910009637 A KR 910009637A
Authority
KR
South Korea
Prior art keywords
vinyl
gaba
production method
hydrolysis
amino
Prior art date
Application number
KR1019900017806A
Other languages
English (en)
Other versions
KR0163042B1 (ko
Inventor
티. 고랄스키 크리스티안
에프. 홉스 죤
에이. 라마나라야난 쿠탄체리
Original Assignee
개리 디. 스트리트
메렐 다우 파마슈티칼즈 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 개리 디. 스트리트, 메렐 다우 파마슈티칼즈 인코포레이티드 filed Critical 개리 디. 스트리트
Publication of KR910009637A publication Critical patent/KR910009637A/ko
Application granted granted Critical
Publication of KR0163042B1 publication Critical patent/KR0163042B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/22—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from lactams, cyclic ketones or cyclic oximes, e.g. by reactions involving Beckmann rearrangement

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyrrole Compounds (AREA)

Abstract

내용 없음

Description

비닐-GABA의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. 5 - 비닐 - 2 - 피롤리디논을 수산화칼륨을 사용하여 염기성 가수분해시킴을 특징으로 하는 4 - 아미노 - 5 - 헥세노산의 제조방법.
  2. 제1항에 있어서, 수산화칼륨이 1.1 내지 1.5 당량의 양으로 존재하는 방법.
  3. 제2항에 있어서, 가수분해를 적어도 물 1.5V/V%및 저급 알칸올을 함유하는 혼합된 용매 시스템중에서 수행하는 방법.
  4. 제3항에 있어서, 저급 알칸올이 이소프로판올인 방법.
  5. 제2항에 있어서, 가수분해를 수중에서 수행하는 방법.
  6. 제2항에 있어서, 생성된 4-아미노-5-헥세노산을 회수하고 정제하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900017806A 1989-11-07 1990-11-05 4-아미노-5-헥센산의 제조방법 KR0163042B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US43270789A 1989-11-07 1989-11-07
US432,707 1989-11-07
US432707 1989-11-07

Publications (2)

Publication Number Publication Date
KR910009637A true KR910009637A (ko) 1991-06-28
KR0163042B1 KR0163042B1 (ko) 1999-01-15

Family

ID=23717279

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900017806A KR0163042B1 (ko) 1989-11-07 1990-11-05 4-아미노-5-헥센산의 제조방법

Country Status (14)

Country Link
US (1) US6090979A (ko)
EP (1) EP0427197B1 (ko)
JP (1) JP3116328B2 (ko)
KR (1) KR0163042B1 (ko)
AT (1) ATE104951T1 (ko)
AU (1) AU629419B2 (ko)
CA (1) CA2028782C (ko)
DE (1) DE69008487T2 (ko)
DK (1) DK0427197T3 (ko)
ES (1) ES2055848T3 (ko)
HU (1) HUT55345A (ko)
IE (1) IE64393B1 (ko)
IL (1) IL96227A (ko)
ZA (1) ZA908751B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546230A1 (en) * 1991-12-10 1993-06-16 Merrell Dow Pharmaceuticals Inc. Novel process for preparing 4-amino-5-hexenoic acid
EP2537827B1 (en) 2011-06-24 2014-06-11 Targeon SAS Process for preparing 4-amino-5-hexenoic acid from succinimide
CN110072521B (zh) 2016-12-16 2022-11-29 爱杜西亚药品有限公司 包含t型钙通道阻断剂的药物组合
CN116621720B (zh) * 2023-07-21 2023-10-27 成都硕德药业有限公司 一种氨己烯酸的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2221441B1 (ko) * 1973-03-13 1976-05-21 Choay Sa
US3960927A (en) 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
US4235778A (en) * 1978-01-30 1980-11-25 Merrell Toraude Et Compagnie 2-Pyrrolidone compounds and processes for making same
US4178463A (en) * 1978-01-30 1979-12-11 Merrell Toraude Et Compagnie Process for making 4-aminohex-5-enoic acid
US4254284A (en) * 1978-01-30 1981-03-03 Merrell Toraude Et Compagnie Process for preparing 4-aminohex-5-ynoic acid
JPS5639050A (en) * 1979-09-06 1981-04-14 Toray Ind Inc Preparation of omega-aminoalkanecarboxylic acid
US4371706A (en) * 1980-05-06 1983-02-01 Phillips Petroleum Company Preparation of alkali metal aminoalkanoates
DK373383A (da) * 1982-08-20 1984-02-21 Midit Fremgangsmaade til fremstilling af omega-aminosyrederivater
GB2133002B (en) 1982-12-30 1986-01-29 Merrell Toraude & Co Process for preparing 4-amino-5-hexenoic acid
US4529818A (en) * 1983-06-07 1985-07-16 Phillips Petroleum Company Continuous process for the production of alkali metal n-methylaminobutyrate

Also Published As

Publication number Publication date
EP0427197B1 (en) 1994-04-27
IE904004A1 (en) 1991-05-08
DE69008487D1 (de) 1994-06-01
AU6559790A (en) 1991-05-16
US6090979A (en) 2000-07-18
ES2055848T3 (es) 1994-09-01
JP3116328B2 (ja) 2000-12-11
IL96227A (en) 1994-10-21
DE69008487T2 (de) 1994-09-08
DK0427197T3 (da) 1994-05-30
AU629419B2 (en) 1992-10-01
IE64393B1 (en) 1995-08-09
IL96227A0 (en) 1991-08-16
HUT55345A (en) 1991-05-28
JPH03153652A (ja) 1991-07-01
ZA908751B (en) 1991-08-28
ATE104951T1 (de) 1994-05-15
EP0427197A1 (en) 1991-05-15
KR0163042B1 (ko) 1999-01-15
CA2028782C (en) 2003-10-14
CA2028782A1 (en) 1991-05-08

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