KR910000792A - 레닌 억제 펩티드, 이들의 제조 방법 및 의약품으로서 이들의 용도 - Google Patents

레닌 억제 펩티드, 이들의 제조 방법 및 의약품으로서 이들의 용도 Download PDF

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Publication number
KR910000792A
KR910000792A KR1019900008406A KR900008406A KR910000792A KR 910000792 A KR910000792 A KR 910000792A KR 1019900008406 A KR1019900008406 A KR 1019900008406A KR 900008406 A KR900008406 A KR 900008406A KR 910000792 A KR910000792 A KR 910000792A
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KR
South Korea
Prior art keywords
group
carbon atoms
formula
general formula
same
Prior art date
Application number
KR1019900008406A
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English (en)
Korean (ko)
Inventor
벤디 볼프강
쉬미트 귄터
크로르 안드레아스
스타쉬 요하네스-페터
Original Assignee
귄티 슈마허, 클라우스 데너
바이엘 악티엔게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 귄티 슈마허, 클라우스 데너, 바이엘 악티엔게젤샤프트 filed Critical 귄티 슈마허, 클라우스 데너
Publication of KR910000792A publication Critical patent/KR910000792A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1019900008406A 1989-06-09 1990-06-08 레닌 억제 펩티드, 이들의 제조 방법 및 의약품으로서 이들의 용도 KR910000792A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE39188965 1989-06-09
DE3918896 1989-06-09
DE39397475 1989-12-01
DE3939747A DE3939747A1 (de) 1989-06-09 1989-12-01 Renininhibitorische peptide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
KR910000792A true KR910000792A (ko) 1991-01-30

Family

ID=25881770

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900008406A KR910000792A (ko) 1989-06-09 1990-06-08 레닌 억제 펩티드, 이들의 제조 방법 및 의약품으로서 이들의 용도

Country Status (12)

Country Link
EP (1) EP0403828A1 (de)
JP (1) JPH0331278A (de)
KR (1) KR910000792A (de)
CN (1) CN1047870A (de)
AU (1) AU5704490A (de)
CA (1) CA2018458A1 (de)
DE (1) DE3939747A1 (de)
FI (1) FI902852A0 (de)
HU (1) HUT54385A (de)
IL (1) IL94639A0 (de)
NO (1) NO902248L (de)
PT (1) PT94278A (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4038921A1 (de) * 1990-12-06 1992-06-11 Bayer Ag Renininhibitorische peptide vom cyclohexylstatin-typ, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4038947A1 (de) * 1990-12-06 1992-06-11 Bayer Ag Dithiolano- und dithianoglycin-haltige renininhibitorische peptide, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
DE4038834A1 (de) * 1990-12-06 1992-06-11 Bayer Ag Optisch reine dithiolanyl- und dithianoaminosaeuren und deren derivate, verfahren zu ihrer herstellung und ihre verwendung
DE4215874A1 (de) * 1992-05-14 1993-11-18 Bayer Ag Dithiolanylglycinhaltige HIV-Proteaseinhibitoren vom Hydroxyethylenisostertyp
EA005310B1 (ru) * 2000-04-10 2004-12-30 Юити Исида Гипотензивные средства
CN104510481A (zh) * 2013-09-26 2015-04-15 温州市高德医疗器械有限公司 高血压三项酶抑制剂真空采血管及其制作方法
KR101540416B1 (ko) * 2014-02-21 2015-07-30 김천기 스패츠 및 아이젠

Also Published As

Publication number Publication date
PT94278A (pt) 1991-02-08
AU5704490A (en) 1990-12-13
DE3939747A1 (de) 1990-12-13
IL94639A0 (en) 1991-04-15
NO902248D0 (no) 1990-05-22
HU903766D0 (en) 1990-11-28
NO902248L (no) 1990-12-10
CN1047870A (zh) 1990-12-19
JPH0331278A (ja) 1991-02-12
FI902852A0 (fi) 1990-06-07
EP0403828A1 (de) 1990-12-27
CA2018458A1 (en) 1990-12-09
HUT54385A (en) 1991-02-28

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WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid