KR910000026B1 - Process for preparing gel for ultrasonic probe - Google Patents

Process for preparing gel for ultrasonic probe Download PDF

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KR910000026B1
KR910000026B1 KR1019890003509A KR890003509A KR910000026B1 KR 910000026 B1 KR910000026 B1 KR 910000026B1 KR 1019890003509 A KR1019890003509 A KR 1019890003509A KR 890003509 A KR890003509 A KR 890003509A KR 910000026 B1 KR910000026 B1 KR 910000026B1
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weight
ultrasonic probe
benzoate
probe
methyl
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KR1019890003509A
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KR900013921A (en
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박수천
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박수천
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves

Abstract

The gel for a ultrasonic probe is prepared by dissolving 6.5-7 wt.% carboxyvinyl copolymer, 1-15 wt.% polypropylene glycol, 1.5-40 wt.% triethanol amine, 0.1 wt.% methyl-para-hydroxy benzeate, 0.1 wt.% butylhydroxy benzoate, 0.8-1 wt.% sodium benzoate, and 0.2-0.3 wt.% methyl cellulose in water, and completely agitating the solution at 15-20 deg.C. The product is useful for ultrasonograph in bringing a good contact between the probe and the body part under inspection.

Description

초음파 푸로브(PROBE)용 교화체(GEL)의 제조방법Manufacturing method of the GEL for ultrasonic probes

본 발명은 초음파 진단기의 탐촉자(探觸子)를 인체에 밀착시키기 위한 교화체의 제조방법에 관한 것으로, 특히 태아심음기 또는 초음파 진단기의 탐촉자(PROBE)를 인체에 밀착시키기 위하여, 점도와 밀착력이 뛰어난 겔을 중간 매개물로 사용하므로서 초음파의 흐름을 정확하게 모니터에 전달하여 선명도가 뛰어난 영상을 얻을 수 있도록 하는 초음파 푸로브용 교화체의 제조방법에 관한 것이다.The present invention relates to a method of manufacturing a human body to closely adhere the transducer of the ultrasonic diagnostic apparatus to the human body, and in particular, in order to closely adhere the transducer (PROBE) of the fetal sounder or ultrasonic diagnostic apparatus to the human body, viscosity and adhesion By using an excellent gel as an intermediate medium, the present invention relates to a method for producing an ultrasonic probe for correcting a body of ultrasonic waves to accurately transmit a flow of ultrasonic waves to a monitor to obtain an excellent image.

일반적으로 초음파 진단시 탐촉자를 인체부위에 밀착시키기 위하여, 물을 인체부위에 바르거나 글리세린 또는 일반 유제를 발라서 밀착효과를 얻는 수단이 이용되고 있으나, 물은 유연성이 없으며, 쉽게 건조하고 기포가 발생하므로 인체부위와 탐촉자와의 밀착 상태가 불량하여 초음파의 흐름에 장애 또는 요인을 완전제거할 수 없고 정확한 영상을 모니터에 전달하지 못하는 결점이 있으며, 글리세린이나 일반 유제의 경우, 기포의 발생이 많고 도포된 유제의 건조현상 및 점도에 의하여 지속적인 밀착 효과를 기대할 수 없어 정확한 영상을 모니터에 전달하지 못할 뿐만 아니라, 진단기중 가장 중요하며 고가인 탐촉자에 글리세린이나 유제가 묻어 이를 제거하기에 어려울 뿐 아니라 탐촉자를 손상시킬 위험성이 높은 결점이 있었다.In general, in order to closely adhere the transducer to the human body during ultrasound diagnosis, a means of applying the adhesion effect by applying water on the human body or applying glycerin or a general emulsion is used, but since water is inflexible, easily dried and bubbles are generated. Due to poor contact between the human body and the probe, it is impossible to completely remove obstacles or factors in the flow of ultrasonic waves, and it is impossible to deliver accurate images to the monitor.In the case of glycerin or general emulsions, bubbles are generated and applied. Due to the drying phenomenon and viscosity of the emulsion, it is not possible to expect a continuous contact effect, and it is not only able to deliver accurate images to the monitor, but also it is difficult to remove the glycerin or emulsion on the most important and expensive transducers of the diagnostic equipment, and damage the transducer. There was a high risk of flaws.

본 발명은 이상과 같은 종래의 결함을 해소하기 위하여 초음파 진단기의 탐촉자와 검사부위의 밀착성 향상을 목적으로 쉽게 건조하지 않으며, 일정한 점장도(粘長渡)를 가쳐 밀착력과 유동성이 뛰어나고 기포의 발생이 없어 초음파 전달 효율이 우수한 취급상 편리한 푸로브용 교화체를 연구한 결과 초음파의 흐름을 영상 모니터에 정확히 전달하여 선명도가 뛰어난 영상을 얻을 수 있을 뿐만 아니라 탐촉자의 수명을 연장시킬 수 있게 되었다.The present invention is not easy to dry for the purpose of improving the adhesion between the probe and the inspection portion of the ultrasonic diagnostic device in order to solve the above-mentioned conventional defects, and has a constant point of view (粘 長 渡) excellent adhesion and fluidity, there is no bubble generation As a result of research on the easy-to-use purifying body for excellent ultrasonic transmission efficiency, it is possible to accurately transmit the flow of ultrasonic waves to an image monitor to obtain an image with excellent clarity and to extend the life of the transducer.

이하 구체적으로 상술하면, 카르복시 비닐 코폴리머를 교화제로 하고, 유화제로서 폴리 프로필렌 글리콜, 형성제로서 트리에타놀 아민, 유연제로써 메틸 셀룰로오즈를 사용하여 이를 약간의 방부제와 필요에 따라 미량의 착색제를 첨가한 후 일정량의 물에 용해시키고 이를 10℃ 내지 20℃의 온도를 유지하면서 충분히 교반하여 믹싱함으로서 유동성과 밀착력이 뛰어나고 기포의 발생이 거의 없으며 쉽게 건조하지 않고 피부에 자극을 주지 않으며 사용후 화장지 또는 타올로써 쉽게 닦아낼 수 있는 교화체를 제조할 수 있어 본 발명에 이르게 되었다.Specifically, the carboxy vinyl copolymer is used as a crosslinking agent, polypropylene glycol as an emulsifier, triethanol amine as a forming agent, and methyl cellulose as a softening agent, followed by addition of a slight preservative and a small amount of a coloring agent as necessary. It is dissolved in a certain amount of water and mixed with sufficient stirring while maintaining a temperature of 10 ° C to 20 ° C. It has excellent fluidity and adhesion, almost no bubbles, does not dry easily, does not irritate the skin, and is easily used as a toilet paper or towel after use. The crosslinkable body which can be wiped off can be manufactured and this invention was reached.

본 발명에 있어서, 교화제로 사용하는 카르복시 비닐 코폴리머는 카포폴(미국 Goodrich Co. 제품 Carbopol No.940)을 사용하며, 방부제로는 메틸 파라 하이록시 벤조네이트로서 다니솔-M(단일화학제품 Danisol-M)과 부틸 파라 하이드록시 벤조네이트로서 다니솔-B(단일화학제품 Danisol-B) 및 소디움 벤조네이트로서 식용 방부제를 각각 사용하고 착색제는 일반적인 식용색소를 사용한다.In the present invention, the carboxy vinyl copolymer to be used as a compatibilizer uses Carpopol (Carbopol No. 940, manufactured by Goodrich Co., USA), and as a preservative, Danisol-M (monochemical Danisol) as methyl para hydroxy benzoate. -M) and butyl para hydroxy benzoate using Danisol-B (monochemical Danisol-B) and sodium benzoate as edible preservatives, respectively, and colorants using common food coloring.

또한 본 발명에 의하면 물 1,000중량%에 대하여 카포폴 6-7중량% 바람직하기로는 6.5-7중량%, P.P.G(poly propylene Gycol : 의약용) 1-15중량%, T.E.A(Tri Ethanol Amin) 1.5-40중량%, 그리고 메틸 셀룰로오즈(D-MC)를 0.2-0.3중량% 첨가하고 방부제로써 D-M(다니솔-M) 및 D-B(다니솔-B)를 각가 0.1중량%, 소디움 벤조네이트(S.B) 0.8-1중량% 첨가한후 10-20℃의 온도, 특히 바람직하기로는 15-20℃의 온도를 유지하면 10-15일간 교반하는 것에 의하여 본 발명이 목적하는 바 양질의 교화체를 제조하게 되는 것이다.Further, according to the present invention, 6-7% by weight of capopol, preferably 6.5-7% by weight, PPG (poly propylene Gycol: for medical use) 1-15% by weight, and TEA (Tri Ethanol Amin) 1.5- 40% by weight, and 0.2-0.3% by weight of methyl cellulose (D-MC), 0.1% by weight of DM (Danisol-M) and DB (Danisol-B) as preservatives, sodium benzoate (SB) 0.8 After the addition of -1% by weight, the temperature of 10-20 ° C, particularly preferably 15-20 ° C, is maintained for 10-15 days, thereby producing a high-quality crosslinked product. .

이때, 교반에 적합한 온도조건이 10-15℃일 경우 15일 가량의 교반기일이 필요하나, 16-20℃에서는 10일간이 소요되어 무려 5일이 단축됨을 알 수 있었고 20℃ 이상에서는 적절한 혼합이 이루어지지 않는 문제점과 함께 교반시간의 단축도 기대할 수 없는 것이었다.At this time, if the temperature condition suitable for stirring is 10-15 ℃ about 15 days of stirrer is required, but it takes 10 days at 16-20 ℃ it can be seen that 5 days shortened how much more suitable mixing above 20 ℃ Along with the problem was not made, the shortening of the stirring time could not be expected.

이하 본 발명을 실시예에 의하여 상세하게 설명한다.Hereinafter, the present invention will be described in detail by way of examples.

[실시예 1]Example 1

하기의 조성으로 되는 혼합물을 15℃의 온도를 유지하여 통상의 교반기를 이용 10일간 서서히 교반한 결과 표 1과 같은 물성을 확인하였다.The mixture having the following composition was kept at a temperature of 15 ° C. and slowly stirred for 10 days using a conventional stirrer to confirm physical properties as shown in Table 1.

Figure kpo00001
Figure kpo00001

[실시예 2]Example 2

하기의 조성으로 되는 혼합물을 10℃에서 15일간 교반한 결과 교반에 소요되는 시간이 실시예 1에 비해 다소 연장되기는 하였으나 표 1과 같은 물성을 확인할 수 있었다.The mixture of the following composition was stirred at 10 ° C. for 15 days, but the time required for stirring was slightly extended compared to Example 1, but physical properties as shown in Table 1 were confirmed.

즉 비교예 1과 비교할때 물성에 특이한 차이가 없었고 유연성에 있어서도 양호하였다.That is, compared with Comparative Example 1, there was no specific difference in physical properties and good in flexibility.

Figure kpo00002
Figure kpo00002

[비교실시예 1]Comparative Example 1

하기 조성의 혼합물을 20℃의 온도에서 10일간 교반하여 표 1의 결과를 얻었다. 이는 종래의 교화체와 비교하여 볼때 일정시간동안 건조되지는 않았으나 진단 소요시간에 충분하지는 못하였다.The mixture of the following composition was stirred for 10 days at the temperature of 20 degreeC, and the result of Table 1 was obtained. This was not dried for a certain period of time compared to the conventional mater, but was not sufficient for the diagnostic time.

Figure kpo00003
Figure kpo00003

[비교실시예 2]Comparative Example 2

하기 조성의 혼합물을 10℃의 온도로 10일간 교반하여 표 1의 결과를 얻었다.The mixture of the following composition was stirred for 10 days at the temperature of 10 degreeC, and the result of Table 1 was obtained.

Figure kpo00004
Figure kpo00004

[비교실시예 3]Comparative Example 3

종래의 방법에 의한 물을 밀착체로서 사용하였으며 그 결과는 표 1과 같다.The water according to the conventional method was used as an adhesive and the results are shown in Table 1.

[표 1]TABLE 1

Figure kpo00005
Figure kpo00005

Claims (1)

카르복시 비닐 코폴리머 6.5-7중량%, 폴리 프로필렌 글리콜 1-15중량%, 트리 에타놀 아민 1.5-40중량%, 메틸 파라 하드록시 벤조네이트 및 부틸히드록시 벤조네이트 각 0.1중량%, 소디움 벤조네이트 0.8-1중량% 및 메틸 셀룰로오즈 0.2-0.3중량%를 물에 용해시킨 다음 15-20℃에서 통상의 교반기를 사용하여 충분히 교반함을 특징으로 하는 초음파 푸로브용 교화체(GEL)의 제조방법.6.5-7% by weight of carboxy vinyl copolymer, 1-15% by weight of polypropylene glycol, 1.5-40% by weight of triethanolamine, 0.1% by weight of methyl para hydroxy benzoate and butylhydroxy benzoate each, sodium benzoate 0.8- 1% by weight and 0.2-0.3% by weight of methyl cellulose are dissolved in water, followed by stirring at 15-20 ° C. using a conventional stirrer.
KR1019890003509A 1989-03-21 1989-03-21 Process for preparing gel for ultrasonic probe KR910000026B1 (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160046907A (en) * 2013-08-26 2016-04-29 창춘 노스이스트 노멀 유니버시티 앤드 진 엔지니어링 씨오 엘티디 Antibacterial medical ultrasonic coupling agent and preparation method thereof

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* Cited by examiner, † Cited by third party
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KR100360278B1 (en) * 2000-03-10 2002-11-09 김정엽 The gel for supersonic probe and its manufacturing method

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160046907A (en) * 2013-08-26 2016-04-29 창춘 노스이스트 노멀 유니버시티 앤드 진 엔지니어링 씨오 엘티디 Antibacterial medical ultrasonic coupling agent and preparation method thereof

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