KR900700500A - 재조합 유전자 기술에 의한 에라스타제 억제 폴리펩티드 제조방법 및 에라스타제 억제 폴리펩티드 - Google Patents
재조합 유전자 기술에 의한 에라스타제 억제 폴리펩티드 제조방법 및 에라스타제 억제 폴리펩티드Info
- Publication number
- KR900700500A KR900700500A KR1019890701620A KR890701620A KR900700500A KR 900700500 A KR900700500 A KR 900700500A KR 1019890701620 A KR1019890701620 A KR 1019890701620A KR 890701620 A KR890701620 A KR 890701620A KR 900700500 A KR900700500 A KR 900700500A
- Authority
- KR
- South Korea
- Prior art keywords
- cys
- pro
- lys
- gly
- val
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormones [GH] (Somatotropin)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62-330219 | 1987-12-28 | ||
JP33021987 | 1987-12-28 | ||
PCT/JP1988/001342 WO1989006239A1 (en) | 1987-12-28 | 1988-12-28 | Elastase inhibiting polypeptides and process for their preparation by genetic recombination |
Publications (2)
Publication Number | Publication Date |
---|---|
KR900700500A true KR900700500A (ko) | 1990-08-13 |
KR910007573B1 KR910007573B1 (ko) | 1991-09-28 |
Family
ID=18230182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019890701620A KR910007573B1 (ko) | 1987-12-28 | 1988-12-28 | 재조합 유전자 기술에 의한 에라스타제 억제 폴리펩티드 제조방법 및 에라스타제 억제 폴리펩티드 |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0346500B1 (ko) |
JP (1) | JP2574048B2 (ko) |
KR (1) | KR910007573B1 (ko) |
AT (1) | ATE109156T1 (ko) |
CA (1) | CA1340877C (ko) |
DE (1) | DE3850878T2 (ko) |
ES (1) | ES2015366A6 (ko) |
WO (1) | WO1989006239A1 (ko) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5871956A (en) * | 1984-12-06 | 1999-02-16 | Amgen Inc. | Recombinant methods for production of serine inhibitors and DNA sequences useful for same |
US6132990A (en) * | 1984-12-06 | 2000-10-17 | Amgen Boulder Inc. | Recombinant methods for production of serine protease inhibitors and DNA sequences useful for same |
US5851983A (en) * | 1987-12-28 | 1998-12-22 | Teijin Limited | Elastase inhibitory polypeptide and process for production thereof by recombinant gene technology |
DE3841873A1 (de) * | 1988-12-13 | 1990-06-21 | Gruenenthal Gmbh | Neue serinprotease-inhibitor-proteine, diese enthaltende arzneimittel, dna-sequenzen, die fuer diese proteine codieren und verfahren zur herstellung dieser proteine, arzneimittel und dna-sequenzen |
WO1991000912A1 (en) * | 1989-07-07 | 1991-01-24 | Massachusetts Institute Of Technology | Production and use of hybrid protease inhibitors |
DE3938971A1 (de) * | 1989-11-24 | 1991-05-29 | Biotechnolog Forschung Gmbh | Leukozytenelastase und kathepsin g blockierendes peptid, dna, vektor, wirtsorganismus und verfahren zu seiner gewinnung sowie pharmazeutisches praeparat |
GB8927722D0 (en) * | 1989-12-07 | 1990-02-07 | British Bio Technology | Proteins and nucleic acids |
JPH06509327A (ja) * | 1991-04-18 | 1994-10-20 | ザ ユー エー ビー リサーチ ファンデーション | エラスターゼ抑制のための組成とその方法 |
US6869925B1 (en) | 1992-09-09 | 2005-03-22 | Amgen Inc. | Inhibition of retrovirus infection |
KR100273620B1 (ko) * | 1992-09-09 | 2000-12-15 | 스티븐 엠. 오드리 | 레트로바이러스 감염의 억제방법 |
US6017880A (en) * | 1994-03-09 | 2000-01-25 | Amgen Inc. | Inhibition of retrovirus infection |
HUT75660A (en) * | 1994-03-23 | 1997-05-28 | Tokyo Tanabe Co | Novel remedy for respiratory-tract viral disease |
US5633227A (en) * | 1994-09-12 | 1997-05-27 | Miles, Inc. | Secretory leukocyte protease inhibitor as an inhibitor of tryptase |
CN1305589A (zh) | 1998-04-17 | 2001-07-25 | 基因创新有限公司 | 采用还原剂的改进型免疫诊断分析 |
WO2001064031A2 (en) * | 2000-03-01 | 2001-09-07 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Slpi knockout mice and methods for wound treatment |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS427042Y1 (ko) * | 1966-11-08 | 1967-04-03 | ||
US4455122A (en) * | 1981-12-14 | 1984-06-19 | United Technologies Corporation | Blade to blade vibration damper |
US4505642A (en) * | 1983-10-24 | 1985-03-19 | United Technologies Corporation | Rotor blade interplatform seal |
US4669959A (en) * | 1984-07-23 | 1987-06-02 | United Technologies Corporation | Breach lock anti-rotation key |
JP2672088B2 (ja) * | 1984-12-06 | 1997-11-05 | サイナ−ゲン バイオロジカルズ,インコ−ポレ−テツド | セリンプロテアーゼ阻害剤の生産のための遺伝子組み換え法と、同じ目的に有用なdna塩基配列 |
DE3600571A1 (de) * | 1986-01-10 | 1987-08-06 | Gruenenthal Gmbh | Dna-sequenzen, die fuer proteine mit der biologischen aktivitaet der husi-typi-inhibitoren codieren, gentechnologische verfahren zur herstellung dieser proteine und diese proteine enthaltende arzneimittel |
-
1988
- 1988-12-21 CA CA000586637A patent/CA1340877C/en not_active Expired - Fee Related
- 1988-12-27 ES ES8803972A patent/ES2015366A6/es not_active Expired - Lifetime
- 1988-12-28 DE DE3850878T patent/DE3850878T2/de not_active Expired - Lifetime
- 1988-12-28 KR KR1019890701620A patent/KR910007573B1/ko not_active IP Right Cessation
- 1988-12-28 WO PCT/JP1988/001342 patent/WO1989006239A1/ja active IP Right Grant
- 1988-12-28 EP EP89900924A patent/EP0346500B1/en not_active Expired - Lifetime
- 1988-12-28 AT AT89900924T patent/ATE109156T1/de not_active IP Right Cessation
- 1988-12-28 JP JP1500811A patent/JP2574048B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA1340877C (en) | 2000-01-18 |
ES2015366A6 (es) | 1990-08-16 |
JP2574048B2 (ja) | 1997-01-22 |
WO1989006239A1 (en) | 1989-07-13 |
EP0346500A1 (en) | 1989-12-20 |
KR910007573B1 (ko) | 1991-09-28 |
EP0346500B1 (en) | 1994-07-27 |
EP0346500A4 (en) | 1991-05-22 |
ATE109156T1 (de) | 1994-08-15 |
DE3850878T2 (de) | 1994-11-10 |
DE3850878D1 (de) | 1994-09-01 |
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Legal Events
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A201 | Request for examination | ||
G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
FPAY | Annual fee payment |
Payment date: 20080917 Year of fee payment: 18 |
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EXPY | Expiration of term |