JPS642577A - Amino acid sequence of human alpha2-plasmin inhibitor and gene fragment - Google Patents

Amino acid sequence of human alpha2-plasmin inhibitor and gene fragment

Info

Publication number
JPS642577A
JPS642577A JP15449587A JP15449587A JPS642577A JP S642577 A JPS642577 A JP S642577A JP 15449587 A JP15449587 A JP 15449587A JP 15449587 A JP15449587 A JP 15449587A JP S642577 A JPS642577 A JP S642577A
Authority
JP
Japan
Prior art keywords
amino acid
acid sequence
plasmin inhibitor
gene fragment
alpha2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15449587A
Other languages
Japanese (ja)
Other versions
JPH012577A (en
Inventor
Yoshihiko Washimi
Yataro Ichikawa
Nobuo Aoki
Masami Muramatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP15449587A priority Critical patent/JPS642577A/en
Priority to DE8787118686T priority patent/DE3777359D1/en
Priority to EP19870118686 priority patent/EP0272609B1/en
Publication of JPH012577A publication Critical patent/JPH012577A/en
Publication of JPS642577A publication Critical patent/JPS642577A/en
Priority to US07/803,896 priority patent/US5221738A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PURPOSE:To provide a gene fragment coding a human alpha2-plasmin inhibitor precursor protein having a specific amino acid sequence and useful for diagnosis, etc. CONSTITUTION:A cDNA of an alpha2-plasmid inhibitor containing 1,209 nucleotides and coding 403 amino acid sequence from the carboxy terminal of a human alpha2-plasmin inhibitor was separated and the precise structure of the carboxy- terminal side of human alpha2-plasmin inhibitor has been clarified by the analysis of the base sequence of the cDNA. It is a gene fragment coding a human alpha2-plasmin inhibitor precursor having an amino acid sequence of from the -29th (Met) to the 452nd (Lys).
JP15449587A 1986-12-19 1987-06-23 Amino acid sequence of human alpha2-plasmin inhibitor and gene fragment Pending JPS642577A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP15449587A JPS642577A (en) 1987-06-23 1987-06-23 Amino acid sequence of human alpha2-plasmin inhibitor and gene fragment
DE8787118686T DE3777359D1 (en) 1986-12-19 1987-12-16 AMINO ACID SEQUENCE OF THE HUMAN ALPHA 2 PLASMIN INHIBITOR AND CDNS, AND GENOIC DNA CODING THIS AMINO ACID SEQUENCE.
EP19870118686 EP0272609B1 (en) 1986-12-19 1987-12-16 Amino acid sequence of human alpha2-plasmin inhibitor and cdna and genomic dna encoding said amino acid sequence
US07/803,896 US5221738A (en) 1986-12-19 1991-12-09 cDNA and genomic DNA encoding the amino acid sequence of human α2 -plasmin inhibition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15449587A JPS642577A (en) 1987-06-23 1987-06-23 Amino acid sequence of human alpha2-plasmin inhibitor and gene fragment

Publications (2)

Publication Number Publication Date
JPH012577A JPH012577A (en) 1989-01-06
JPS642577A true JPS642577A (en) 1989-01-06

Family

ID=15585496

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15449587A Pending JPS642577A (en) 1986-12-19 1987-06-23 Amino acid sequence of human alpha2-plasmin inhibitor and gene fragment

Country Status (1)

Country Link
JP (1) JPS642577A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006675A1 (en) * 1989-11-02 1991-05-16 Hoechst Japan Limited New oligonucleotide probe

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991006675A1 (en) * 1989-11-02 1991-05-16 Hoechst Japan Limited New oligonucleotide probe

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