KR900009046A - 치구 억제제 - Google Patents
치구 억제제 Download PDFInfo
- Publication number
- KR900009046A KR900009046A KR1019890019541A KR890019541A KR900009046A KR 900009046 A KR900009046 A KR 900009046A KR 1019890019541 A KR1019890019541 A KR 1019890019541A KR 890019541 A KR890019541 A KR 890019541A KR 900009046 A KR900009046 A KR 900009046A
- Authority
- KR
- South Korea
- Prior art keywords
- jig
- pharmaceutically acceptable
- acceptable salt
- toothpaste
- hydrogen atom
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/22—Gas releasing
- A61K2800/222—Effervescent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Confectionery (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Dental Preparations (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 물질 1의 부재하에 배양된 치아의 표면에서 생장한 미생물의 형태를 나타내는 주사 전자 현미경도(x4000)이고,
제2도는 물질 2의 존재하에 배양된 치아의 표면에서 생장한 미생물의 형태를 나타내는 주사 전자 현미경도(x4000)이다.
Claims (7)
- 하기 일반식 (I)의 화합물 또는 그의 약학적으로 허용가능한 염을 함유하는 치구 억제 조성물.[상기식 중, R1, R2및 R3는 동일 또는 상이하며, 각각 수소 원자 또는 메틸기이다]
- 제1항에 있어서, 상기 화합물 또는 약학적으로 허용가능한 염을 0.05 w/v%~5.0 w/v%의 비율로 함유하는 치구 억제 조성물.
- 제1 또는 2항에 있어서, 상기 약학적으로 허용가능한 염이 상응하는 나트륨, 칼륨, 칼슘 또는 마그네슘염인 치구 억제 조성물.
- 제3항에 있어서, 조성물이 크림 치약, 분말 치약, 양치질약용 타블릿, 트로키제, 구강 연고제 또는 추잉껌의 형태인 치구 억제 조성물.
- 제3항에 있어서, 조성물이 액체 치약, 구강 청정제 또는 액체 양치질약의 형태이고, 조성물의 pH가 약 4.0~약 9.0인 치구 억제 조성물.
- 하기 일반식 (I)의 화합물 또는 그의 약학적으로 허용가능한 염 유효량을 크림 치약, 분말 치약, 액체 치약, 구강 청정제, 액체 양치질약, 트로키제, 추잉 껌 또는 구강연고제의 형태로 포유 동물의 구강에 투여함을 특징으로 하는 포유 동물에서의 치구 형성 예방 방법.[상기식 중, R1, R2및 R3는 동일 또는 상이하며, 각각 수소원자 또는 메탈기이다]
- 하기 일반식 (I)의 치구 억제제 또는 그의 약학적으로 허용가능한 염을 물 및 에탄올과 혼합하고, 이 혼합물을 용해시킨 다음 용액의 pH를 4.0~9.0으로 조정함을 특징으로 하는 수성 치구 형성 억제 조성물의 제조 방법.[상기식 중, R1, R2및 R3는 동일 또는 상이하며, 각각 수소원자 또는 메틸기이다]※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63-330086 | 1988-12-26 | ||
JP63330086A JP2736794B2 (ja) | 1988-12-26 | 1988-12-26 | 歯垢生成防止剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR900009046A true KR900009046A (ko) | 1990-07-02 |
KR960014780B1 KR960014780B1 (en) | 1996-10-19 |
Family
ID=18228629
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR89019541A KR960014780B1 (en) | 1988-12-26 | 1989-12-26 | Dental plaque inhibitor composition and its preparation |
Country Status (8)
Country | Link |
---|---|
US (1) | US4973472A (ko) |
EP (1) | EP0376162B1 (ko) |
JP (1) | JP2736794B2 (ko) |
KR (1) | KR960014780B1 (ko) |
AT (1) | ATE94050T1 (ko) |
CA (1) | CA2004903A1 (ko) |
DE (1) | DE68909025T2 (ko) |
ES (1) | ES2058458T3 (ko) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5094843A (en) * | 1990-09-10 | 1992-03-10 | Beecham Inc. | Antimicrobial toothpaste |
FR2679904A1 (fr) * | 1991-08-01 | 1993-02-05 | Lvmh Rech | Utilisation d'un phosphate de tocopherol, ou de l'un de ses derives, pour la preparation de compositions cosmetiques, ou pharmaceutiques et compositions ainsi obtenues. |
US5622940A (en) * | 1994-07-14 | 1997-04-22 | Alpha-Beta Technology | Inhibition of infection-stimulated oral tissue destruction by β(1,3)-glucan |
NZ530915A (en) * | 2004-02-02 | 2004-08-27 | Bernard Charles Sherman | Antimicrobial oral rinse solid composition to be dispersed in water prior to use in the oral cavity |
CN105007987B (zh) * | 2013-03-15 | 2017-11-10 | 高露洁-棕榄公司 | 口腔护理组合物及其制备方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5238113A (en) * | 1975-09-19 | 1977-03-24 | Hitachi Ltd | Magnetic field circuit in direct current motor |
JPS561070A (en) * | 1979-06-15 | 1981-01-08 | Ricoh Co Ltd | Original pressure-contacting device of copying machine |
JPS5821603A (ja) * | 1981-07-29 | 1983-02-08 | Kyowa Kaseihin Kk | 防虫防かび剤 |
JPS5912274A (ja) * | 1982-07-12 | 1984-01-21 | 日本ベルテイング株式会社 | 二重ベルト式冷却機の上部ベルト冷却装置 |
JPS59219295A (ja) * | 1983-05-30 | 1984-12-10 | Senjiyu Seiyaku Kk | リン酸ジエステルまたはその塩およびそれらの製造法 |
JPS62145019A (ja) * | 1985-12-19 | 1987-06-29 | Senjiyu Seiyaku Kk | 抗炎症剤 |
JPS62205091A (ja) * | 1986-03-04 | 1987-09-09 | Senjiyu Seiyaku Kk | 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤 |
IT1204901B (it) * | 1986-06-25 | 1989-03-10 | Iscofar Sas | Composizioni contenenti acido usnico o suoi derivati atte all'impiego nel trattamento della carie dentaria |
JPS6324488A (ja) * | 1986-07-17 | 1988-02-01 | 東芝テック株式会社 | 電子式キヤツシユレジスタ |
JPS6326083A (ja) * | 1986-07-18 | 1988-02-03 | Nippon Kokan Kk <Nkk> | X線テレビ装置 |
JPS63119416A (ja) * | 1986-11-07 | 1988-05-24 | Yasutake Hichi | 抗齲蝕剤 |
JPH0678214B2 (ja) * | 1986-12-02 | 1994-10-05 | 株式会社資生堂 | 頭髪化粧料 |
JPH0781138B2 (ja) * | 1986-12-02 | 1995-08-30 | 株式会社資生堂 | 抗酸化剤 |
JP2526059B2 (ja) * | 1987-04-28 | 1996-08-21 | 千寿製薬株式会社 | 抗潰瘍剤 |
JP2605714B2 (ja) * | 1987-05-11 | 1997-04-30 | ライオン株式会社 | 口腔用組成物 |
-
1988
- 1988-12-26 JP JP63330086A patent/JP2736794B2/ja not_active Expired - Lifetime
-
1989
- 1989-12-07 CA CA002004903A patent/CA2004903A1/en not_active Abandoned
- 1989-12-18 US US07/451,745 patent/US4973472A/en not_active Expired - Fee Related
- 1989-12-21 DE DE89123675T patent/DE68909025T2/de not_active Expired - Fee Related
- 1989-12-21 AT AT89123675T patent/ATE94050T1/de not_active IP Right Cessation
- 1989-12-21 ES ES89123675T patent/ES2058458T3/es not_active Expired - Lifetime
- 1989-12-21 EP EP89123675A patent/EP0376162B1/en not_active Expired - Lifetime
- 1989-12-26 KR KR89019541A patent/KR960014780B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE68909025T2 (de) | 1994-01-05 |
EP0376162A2 (en) | 1990-07-04 |
ES2058458T3 (es) | 1994-11-01 |
EP0376162A3 (en) | 1991-06-19 |
JP2736794B2 (ja) | 1998-04-02 |
CA2004903A1 (en) | 1990-06-26 |
US4973472A (en) | 1990-11-27 |
KR960014780B1 (en) | 1996-10-19 |
DE68909025D1 (de) | 1993-10-14 |
JPH02172910A (ja) | 1990-07-04 |
EP0376162B1 (en) | 1993-09-08 |
ATE94050T1 (de) | 1993-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |