KR900009046A - 치구 억제제 - Google Patents

치구 억제제 Download PDF

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Publication number
KR900009046A
KR900009046A KR1019890019541A KR890019541A KR900009046A KR 900009046 A KR900009046 A KR 900009046A KR 1019890019541 A KR1019890019541 A KR 1019890019541A KR 890019541 A KR890019541 A KR 890019541A KR 900009046 A KR900009046 A KR 900009046A
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KR
South Korea
Prior art keywords
jig
pharmaceutically acceptable
acceptable salt
toothpaste
hydrogen atom
Prior art date
Application number
KR1019890019541A
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English (en)
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KR960014780B1 (en
Inventor
마이유미 모리사끼
Original Assignee
요시다 쇼지
센쥬 세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 요시다 쇼지, 센쥬 세이야꾸 가부시끼가이샤 filed Critical 요시다 쇼지
Publication of KR900009046A publication Critical patent/KR900009046A/ko
Application granted granted Critical
Publication of KR960014780B1 publication Critical patent/KR960014780B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/22—Gas releasing
    • A61K2800/222—Effervescent

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
  • Dental Preparations (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

내용 없음.

Description

치구 억제제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 물질 1의 부재하에 배양된 치아의 표면에서 생장한 미생물의 형태를 나타내는 주사 전자 현미경도(x4000)이고,
제2도는 물질 2의 존재하에 배양된 치아의 표면에서 생장한 미생물의 형태를 나타내는 주사 전자 현미경도(x4000)이다.

Claims (7)

  1. 하기 일반식 (I)의 화합물 또는 그의 약학적으로 허용가능한 염을 함유하는 치구 억제 조성물.
    [상기식 중, R1, R2및 R3는 동일 또는 상이하며, 각각 수소 원자 또는 메틸기이다]
  2. 제1항에 있어서, 상기 화합물 또는 약학적으로 허용가능한 염을 0.05 w/v%~5.0 w/v%의 비율로 함유하는 치구 억제 조성물.
  3. 제1 또는 2항에 있어서, 상기 약학적으로 허용가능한 염이 상응하는 나트륨, 칼륨, 칼슘 또는 마그네슘염인 치구 억제 조성물.
  4. 제3항에 있어서, 조성물이 크림 치약, 분말 치약, 양치질약용 타블릿, 트로키제, 구강 연고제 또는 추잉껌의 형태인 치구 억제 조성물.
  5. 제3항에 있어서, 조성물이 액체 치약, 구강 청정제 또는 액체 양치질약의 형태이고, 조성물의 pH가 약 4.0~약 9.0인 치구 억제 조성물.
  6. 하기 일반식 (I)의 화합물 또는 그의 약학적으로 허용가능한 염 유효량을 크림 치약, 분말 치약, 액체 치약, 구강 청정제, 액체 양치질약, 트로키제, 추잉 껌 또는 구강연고제의 형태로 포유 동물의 구강에 투여함을 특징으로 하는 포유 동물에서의 치구 형성 예방 방법.
    [상기식 중, R1, R2및 R3는 동일 또는 상이하며, 각각 수소원자 또는 메탈기이다]
  7. 하기 일반식 (I)의 치구 억제제 또는 그의 약학적으로 허용가능한 염을 물 및 에탄올과 혼합하고, 이 혼합물을 용해시킨 다음 용액의 pH를 4.0~9.0으로 조정함을 특징으로 하는 수성 치구 형성 억제 조성물의 제조 방법.
    [상기식 중, R1, R2및 R3는 동일 또는 상이하며, 각각 수소원자 또는 메틸기이다]
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR89019541A 1988-12-26 1989-12-26 Dental plaque inhibitor composition and its preparation KR960014780B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP63-330086 1988-12-26
JP63330086A JP2736794B2 (ja) 1988-12-26 1988-12-26 歯垢生成防止剤

Publications (2)

Publication Number Publication Date
KR900009046A true KR900009046A (ko) 1990-07-02
KR960014780B1 KR960014780B1 (en) 1996-10-19

Family

ID=18228629

Family Applications (1)

Application Number Title Priority Date Filing Date
KR89019541A KR960014780B1 (en) 1988-12-26 1989-12-26 Dental plaque inhibitor composition and its preparation

Country Status (8)

Country Link
US (1) US4973472A (ko)
EP (1) EP0376162B1 (ko)
JP (1) JP2736794B2 (ko)
KR (1) KR960014780B1 (ko)
AT (1) ATE94050T1 (ko)
CA (1) CA2004903A1 (ko)
DE (1) DE68909025T2 (ko)
ES (1) ES2058458T3 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5094843A (en) * 1990-09-10 1992-03-10 Beecham Inc. Antimicrobial toothpaste
FR2679904A1 (fr) * 1991-08-01 1993-02-05 Lvmh Rech Utilisation d'un phosphate de tocopherol, ou de l'un de ses derives, pour la preparation de compositions cosmetiques, ou pharmaceutiques et compositions ainsi obtenues.
US5622940A (en) * 1994-07-14 1997-04-22 Alpha-Beta Technology Inhibition of infection-stimulated oral tissue destruction by β(1,3)-glucan
NZ530915A (en) * 2004-02-02 2004-08-27 Bernard Charles Sherman Antimicrobial oral rinse solid composition to be dispersed in water prior to use in the oral cavity
US9561160B2 (en) * 2013-03-15 2017-02-07 Colgate-Palmolive Company Oral care composition and processes for preparing same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5238113A (en) * 1975-09-19 1977-03-24 Hitachi Ltd Magnetic field circuit in direct current motor
JPS561070A (en) * 1979-06-15 1981-01-08 Ricoh Co Ltd Original pressure-contacting device of copying machine
JPS5821603A (ja) * 1981-07-29 1983-02-08 Kyowa Kaseihin Kk 防虫防かび剤
JPS5912274A (ja) * 1982-07-12 1984-01-21 日本ベルテイング株式会社 二重ベルト式冷却機の上部ベルト冷却装置
JPS59219295A (ja) * 1983-05-30 1984-12-10 Senjiyu Seiyaku Kk リン酸ジエステルまたはその塩およびそれらの製造法
JPS62145019A (ja) * 1985-12-19 1987-06-29 Senjiyu Seiyaku Kk 抗炎症剤
JPS62205091A (ja) * 1986-03-04 1987-09-09 Senjiyu Seiyaku Kk 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
IT1204901B (it) * 1986-06-25 1989-03-10 Iscofar Sas Composizioni contenenti acido usnico o suoi derivati atte all'impiego nel trattamento della carie dentaria
JPS6324488A (ja) * 1986-07-17 1988-02-01 東芝テック株式会社 電子式キヤツシユレジスタ
JPS6326083A (ja) * 1986-07-18 1988-02-03 Nippon Kokan Kk <Nkk> Ｘ線テレビ装置
JPS63119416A (ja) * 1986-11-07 1988-05-24 Yasutake Hichi 抗齲蝕剤
JPH0781138B2 (ja) * 1986-12-02 1995-08-30 株式会社資生堂 抗酸化剤
JPH0678214B2 (ja) * 1986-12-02 1994-10-05 株式会社資生堂 頭髪化粧料
JP2526059B2 (ja) * 1987-04-28 1996-08-21 千寿製薬株式会社 抗潰瘍剤
JP2605714B2 (ja) * 1987-05-11 1997-04-30 ライオン株式会社 口腔用組成物

Also Published As

Publication number Publication date
KR960014780B1 (en) 1996-10-19
DE68909025D1 (de) 1993-10-14
EP0376162A3 (en) 1991-06-19
US4973472A (en) 1990-11-27
ATE94050T1 (de) 1993-09-15
ES2058458T3 (es) 1994-11-01
CA2004903A1 (en) 1990-06-26
JPH02172910A (ja) 1990-07-04
JP2736794B2 (ja) 1998-04-02
EP0376162A2 (en) 1990-07-04
DE68909025T2 (de) 1994-01-05
EP0376162B1 (en) 1993-09-08

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