KR900008035A - 인체 하이브리도마 제작용의 친 세포주 - Google Patents
인체 하이브리도마 제작용의 친 세포주 Download PDFInfo
- Publication number
- KR900008035A KR900008035A KR1019890016265A KR890016265A KR900008035A KR 900008035 A KR900008035 A KR 900008035A KR 1019890016265 A KR1019890016265 A KR 1019890016265A KR 890016265 A KR890016265 A KR 890016265A KR 900008035 A KR900008035 A KR 900008035A
- Authority
- KR
- South Korea
- Prior art keywords
- cell line
- human
- derived therefrom
- cell
- human immunoglobulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
- C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (14)
- 인체면역글로블린 합성 세포주에 유래하고, 자기 증식능과 세포 융합능을 가지는 인체면역 글로블린 비합성 돌연변이 세포주 및 그것에 유래하는 세포주.
- 제1항에 있어서, 인체 면역 글로블린 합성세포주가 인체 미엘로마 세포와 인체 임파구세포의 융합 세포주인 인체 면역 글로부릴 비합성 돌연 변이 세포주 및 그것에 유래하는 세포주.
- 제2항에 있어서, 인체 미엘로마세포가 RPMI 8226에서 유래하는 인체 면역 글로블린 비합성 돌연변이 세포주 및 그것에 유래하는 세포주.
- 제2항에 있어서, 인체임파구세포가 GM 1500에서 유래하는 인체면역 글로블린 비합성 돌연변이 세포주 및 그것에 유래하는 세포주.
- 제1항에 있어서, 인체 면역 글로블린 합성 세포주가 ATCC CRL 8658인 인체 면역 글로블린 비합성 돌연변이 세포주 및 그것에 유래하는 세포주.
- 미공연 조기 제2128호, 제2129호, 제2615호의 세포주 및 그것에 유래하는 세포주.
- 제1항 내지 제6항의 세포주로 부터 선별에 의하여 얻어지는 세포주 및 그것에 유래하는 세포주.
- 제1항 내지 제7항의 세포주에 돌연변이를 유발시킴으로써 얻어지는 세포주 및 그것에 유래하는 세포주.
- 제1항 내지 제8항중 어느 한항에 있어서, 인체항체 산생세포와의 융합능을 가지는 것을 특징으로 하는 세포주.
- 제9항에 있어서, 인체항체산생세포가 엡스타인, 바(Epstein-Barr)바이러스형질 전환 세포인 세포주.
- 제9항에 있어서, 인체항체 산생세포가 B임파구인 세포주.
- 제1항 내지 제11항에 기재된 세포주의 제작방법.
- 제1항 내지 제12항에 기재된 세포주와 인체항체 산생세포와의 세포 융합방법.
- 제1항 내지 제12항에 기재된 세포주와 인체 항체 산생세포와의 세포융합에 의하여 얻어지는 인체 하이브리도마 및 그것에 유래하는 세포주.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63-281461 | 1988-11-09 | ||
JP28146188 | 1988-11-09 | ||
JP28146088 | 1988-11-09 | ||
JP63-281460 | 1988-11-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR900008035A true KR900008035A (ko) | 1990-06-02 |
Family
ID=26554197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019890016265A KR900008035A (ko) | 1988-11-09 | 1989-11-09 | 인체 하이브리도마 제작용의 친 세포주 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0368662B1 (ko) |
JP (1) | JP2764101B2 (ko) |
KR (1) | KR900008035A (ko) |
AU (1) | AU617553B2 (ko) |
CA (1) | CA2002067A1 (ko) |
DE (1) | DE68918229T2 (ko) |
DK (1) | DK553189A (ko) |
ES (1) | ES2059783T3 (ko) |
FI (1) | FI895316A0 (ko) |
NO (1) | NO894386L (ko) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5730977A (en) * | 1995-08-21 | 1998-03-24 | Mitsui Toatsu Chemicals, Inc. | Anti-VEGF human monoclonal antibody |
FR2817869B1 (fr) * | 2000-12-07 | 2005-01-14 | Technopharm | Anticorps monoclonal humain dirige contre le virus influenza ou un fragment de celui-ci |
CN113125227A (zh) * | 2020-12-25 | 2021-07-16 | 上海乐辰生物科技有限公司 | 核型分析用制备高分辨染色体的秋水溶液及应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3167442D1 (en) * | 1980-07-07 | 1985-01-10 | Nat Res Dev | Improvements in or relating to cell lines |
NZ198851A (en) | 1980-11-07 | 1984-07-31 | Wistar Inst | Stable,continuous human myeloma cell line capable of hybridisation with antibody-producing cells:production of hybrid cell line |
US4451570A (en) | 1981-03-26 | 1984-05-29 | The Regents Of The University Of California | Immunoglobulin-secreting human hybridomas from a cultured human lymphoblastoid cell line |
US4647535A (en) | 1981-08-12 | 1987-03-03 | Research Corporation | Human nonsecretory plasmacytoid cell line |
US4434230A (en) | 1981-08-12 | 1984-02-28 | Research Corporation | Human nonsecretory plasmacytoid cell line |
US4529694A (en) * | 1982-04-16 | 1985-07-16 | The Children's Medical Center Corporation | Cell fusion |
JPS59132885A (ja) | 1983-01-20 | 1984-07-31 | Suntory Ltd | 新規細胞ライン |
CA1218947A (en) | 1983-04-06 | 1987-03-10 | Pearl M.J. Chen | Human hybrid cell lines |
JPS60141285A (ja) * | 1983-12-29 | 1985-07-26 | Hironori Murakami | ヒトハイブリド−マ作成用親細胞株 |
US4624921A (en) | 1984-04-26 | 1986-11-25 | Cetus Corporation | Human lymphoblastold cell line and hybridomas derived therefrom |
US4693975A (en) * | 1984-11-20 | 1987-09-15 | The Wistar Institute | Human hybridroma fusion partner for production of human monoclonal antibodies |
US4720459A (en) * | 1985-02-14 | 1988-01-19 | Medical College Of Wisconsin Research Foundation, Inc. | Myelomas for producing human/human hybridomas |
JPS61242575A (ja) | 1985-04-22 | 1986-10-28 | Wakunaga Seiyaku Kk | G418耐性ヒト−バ−キツトリンパ腫由来細胞 |
JP2599123B2 (ja) * | 1985-12-28 | 1997-04-09 | 萩原 義秀 | 新規なヒトbセル・リンパ芽球細胞変異株 |
JPS63185374A (ja) * | 1987-01-28 | 1988-07-30 | Morinaga & Co Ltd | ヒト−ヒトハイブリド−マ作製用親細胞株 |
US5001065A (en) | 1987-05-27 | 1991-03-19 | Cetus Corporation | Human cell line and triomas, antibodies, and transformants derived therefrom |
-
1989
- 1989-11-02 CA CA002002067A patent/CA2002067A1/en not_active Abandoned
- 1989-11-03 NO NO89894386A patent/NO894386L/no unknown
- 1989-11-06 DK DK553189A patent/DK553189A/da not_active Application Discontinuation
- 1989-11-08 JP JP1288764A patent/JP2764101B2/ja not_active Expired - Lifetime
- 1989-11-08 FI FI895316A patent/FI895316A0/fi not_active IP Right Cessation
- 1989-11-08 AU AU44496/89A patent/AU617553B2/en not_active Ceased
- 1989-11-09 KR KR1019890016265A patent/KR900008035A/ko not_active Application Discontinuation
- 1989-11-09 DE DE68918229T patent/DE68918229T2/de not_active Expired - Fee Related
- 1989-11-09 EP EP89311614A patent/EP0368662B1/en not_active Expired - Lifetime
- 1989-11-09 ES ES89311614T patent/ES2059783T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2764101B2 (ja) | 1998-06-11 |
DK553189D0 (da) | 1989-11-06 |
DE68918229T2 (de) | 1995-05-04 |
ES2059783T3 (es) | 1994-11-16 |
EP0368662A3 (en) | 1990-10-24 |
CA2002067A1 (en) | 1990-05-09 |
JPH02242671A (ja) | 1990-09-27 |
EP0368662B1 (en) | 1994-09-14 |
AU617553B2 (en) | 1991-11-28 |
FI895316A0 (fi) | 1989-11-08 |
AU4449689A (en) | 1990-05-17 |
NO894386D0 (no) | 1989-11-03 |
DK553189A (da) | 1990-05-10 |
EP0368662A2 (en) | 1990-05-16 |
NO894386L (no) | 1990-05-10 |
DE68918229D1 (de) | 1994-10-20 |
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