KR900006322A - 시스 3-아미노-4-〔2-(2-푸릴)비닐〕-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 디-p-톨루오일-타르타르산 염 - Google Patents

시스 3-아미노-4-〔2-(2-푸릴)비닐〕-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 디-p-톨루오일-타르타르산 염 Download PDF

Info

Publication number
KR900006322A
KR900006322A KR1019890014915A KR890014915A KR900006322A KR 900006322 A KR900006322 A KR 900006322A KR 1019890014915 A KR1019890014915 A KR 1019890014915A KR 890014915 A KR890014915 A KR 890014915A KR 900006322 A KR900006322 A KR 900006322A
Authority
KR
South Korea
Prior art keywords
toluoyl
tartaric acid
cis
methoxycarbonylmethyl
furyl
Prior art date
Application number
KR1019890014915A
Other languages
English (en)
Inventor
브렌난 존
마이클 액크리취 토마스
Original Assignee
리로이 휘테커
일라이 릴리 앤드 캄파니
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 리로이 휘테커, 일라이 릴리 앤드 캄파니 filed Critical 리로이 휘테커
Publication of KR900006322A publication Critical patent/KR900006322A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

내용 없음

Description

시스 3-아미노-4-[2-(2-푸릴)비닐]-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 디-p-톨루오일-타르타르산 염.
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. (a)시스 αα/ββ라세메이트의 극성 유기 용액을 광학적 활성 디-p-톨루오일 타르타르산 적어도 약 0.5몰당량과 접촉시키고 ; (b) 이에 의해 형성된 불용성 염을 분리시키는 단계들을 포함하는 시스 αα/ββ-3-아미노-4-[2-(푸릴)비닐-1-일]-1-메톡시카보닐메틸-아제티딘-2-온을 그의 성분 에난티오머들로 분할하는 방법.
  2. 제 1 항에 있어서, 상기 이용된 극성 유기 용매가 아세토니트릴 또는 1,2-디클로로에탄인 방법.
  3. 제 2 항에 있어서, 분할제로서 디-p-톨루오일-(D)-타르타르산을 이용하는 방법.
  4. 제 2 항에 있어서, 분할제로서 디-p-톨루오일-(L)-타르타르산을 이용하는 방법.
  5. 시스 ββ-3-아미노-4-[2-(푸릴)비닐-1-일]-1-메톡시카보닐메틸-아제티딘-2-온의 디-p-톨루오일-(D)-타르타르산 염.
  6. 시스 αα-3-아미노-4-[2-(푸릴)비닐-1-일]-1-메톡시카보닐메틸-아제티딘-2-온의 디-p-톨루오일-(L)-타르타르산 염.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890014915A 1988-10-17 1989-10-17 시스 3-아미노-4-〔2-(2-푸릴)비닐〕-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 디-p-톨루오일-타르타르산 염 KR900006322A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US258,918 1981-04-30
US07/258,918 US4931557A (en) 1988-10-17 1988-10-17 Method of resolving cis 3-amino-4-(2-furyl)vinyl)-1-methoxycarbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof

Publications (1)

Publication Number Publication Date
KR900006322A true KR900006322A (ko) 1990-05-07

Family

ID=22982690

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019890014915A KR900006322A (ko) 1988-10-17 1989-10-17 시스 3-아미노-4-〔2-(2-푸릴)비닐〕-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 디-p-톨루오일-타르타르산 염

Country Status (12)

Country Link
US (1) US4931557A (ko)
EP (1) EP0365213B1 (ko)
JP (1) JPH02169588A (ko)
KR (1) KR900006322A (ko)
AT (1) ATE116314T1 (ko)
CA (1) CA1280431C (ko)
DE (1) DE68920265T2 (ko)
ES (1) ES2065396T3 (ko)
GR (1) GR3015499T3 (ko)
HU (1) HU207516B (ko)
IE (1) IE65190B1 (ko)
IL (1) IL91958A0 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030725A (en) * 1990-02-06 1991-07-09 Eli Lilly And Company Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one using (-)-DAG
FR2664600B1 (fr) * 1990-07-16 1994-09-02 Rhone Poulenc Sante Nouveau sel derive de la dialcoylaminoalcoyl-sulfonyl-26 pristinamycine iib.
MX9605611A (es) * 1994-05-16 1998-05-31 Merrell Pharma Inc Procedimiento y sales diastereomericas utiles para la resolucion optica de a-(4-(1,1-dimetiletil)fenil)-4-(hidroxidifenil-metil)-1-pipe ridinbutanol racemico y compuestos derivados.
US6462229B1 (en) 1998-09-23 2002-10-08 Lonza Ltd. Process for the preparation of (-)-α-(difluoromethyl)ornithine-monohydrochloride monohydrate
CN101468986B (zh) * 2007-12-26 2010-12-29 香港南北兄弟国际投资有限公司 一种二氢嘧啶消旋化合物的拆分方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003913A (en) * 1973-07-09 1977-01-18 Ayerst Mckenna And Harrison Ltd. Pyrano- and thiopyranoindole derivatives, compositions and methods of use
GB1427097A (en) * 1973-10-18 1976-03-03 Ici Ltd Optically-active morpholine derivatives
US4072698A (en) * 1976-12-02 1978-02-07 The Upjohn Company Resolution of aminonitriles
IN148930B (ko) * 1977-09-19 1981-07-25 Hoffmann La Roche
DE3410380A1 (de) * 1984-03-21 1985-10-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics

Also Published As

Publication number Publication date
JPH02169588A (ja) 1990-06-29
EP0365213A2 (en) 1990-04-25
IE65190B1 (en) 1995-10-04
IL91958A0 (en) 1990-07-12
HUT58076A (en) 1992-01-28
HU207516B (en) 1993-04-28
US4931557A (en) 1990-06-05
ATE116314T1 (de) 1995-01-15
GR3015499T3 (en) 1995-06-30
ES2065396T3 (es) 1995-02-16
HU895326D0 (en) 1990-01-28
CA1280431C (en) 1991-02-19
EP0365213A3 (en) 1991-11-06
DE68920265T2 (de) 1995-05-24
EP0365213B1 (en) 1994-12-28
DE68920265D1 (de) 1995-02-09
IE893323L (en) 1990-04-17

Similar Documents

Publication Publication Date Title
DK19988D0 (da) Fremgangsmaade til fremstilling af optisk aktive cyanhydriner
ES2037723T3 (es) Amidinacion selectiva de diaminas.
DK489686A (da) Fremgangsmaade til fremstilling af 2-keto-l-gulonsyre
KR900006323A (ko) 시스 3-아미노-4-[2-(2-푸릴)에트-1-일]-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 말산염.
KR900006322A (ko) 시스 3-아미노-4-〔2-(2-푸릴)비닐〕-1-메톡시카보닐메틸-아제티딘-2-온의 분할방법 및 그의 디-p-톨루오일-타르타르산 염
DE3882078D1 (de) Amperometrische methode zur titration von nadh (1,4-dihydronicotinamid-adenine-dinucleotide) in loesung.
IT8121263A0 (it) Processo per la preparazione disolfuri organici.
KR910002844A (ko) 시스 3-아미노-4-[2-(2-푸릴)에트-1-일]-1- 메톡시카보닐 메틸-아제티딘-2-온의 분할방법
DE3777934D1 (de) Herstellung von organischen fluessigkeiten.
PT89764A (pt) Processo de eliminacao, atraves de evaporacao das aguas transbordantes das galgas com o emprego de brulho exausto dentro de uma maquina de exsicacao
KR910015570A (ko) 시스 3-아미노-4-[2-(2-푸릴)에트-1-일]-1-메톡시카보닐메틸-아제티딘-2-온의 분해방법
DE3765630D1 (de) Aktives, hydraulisch daempfendes motorlager.
DE69011583D1 (de) Biologische Herstellung von Cyclohexadiendiolen.
FR2701482B1 (fr) Nouveaux composés de type pipéridine-triazine appropriés en tant que stabilisateurs de matières organiques.
KR880003897A (ko) 디아스테레오머의 분리
KR900003373A (ko) 프로키랄 디올로부터의 키랄 하이드록시 카복실산
KR920703518A (ko) 보다 활성인 종의 함량이 많은 사이퍼메트린 또는 사이플루트린 이성체 혼합물의 제조방법
DE59006125D1 (de) D-Malat-Bestimmung.
KR890003660A (ko) 4-(4-히드록시페닐)-시클로헥산올의 제조방법
SU968413A1 (ru) Раствор дл ослаблени горных пород
DE3784877D1 (de) Herstellungsverfahren von 2,6-dichlorbenzylalkohol.
KR910013332A (ko) 알루미늄전해 콘덴서용 전해질(electrolyte)의 안티솔벤트(Anti-solvent)화
KR860001527A (ko) 소나무 마름병방지약제의 제조방법
KR830002856A (ko) 피리돈 분산염료의 제조방법
JPS52105282A (en) Immobilization of enzyme

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application