KR900005471B1 - 2H-[1]벤즈옥세피노[5,4-b]-1,4-옥사진 유도체 및 이의 제조방법 - Google Patents

2H-[1]벤즈옥세피노[5,4-b]-1,4-옥사진 유도체 및 이의 제조방법 Download PDF

Info

Publication number
KR900005471B1
KR900005471B1 KR1019840000692A KR840000692A KR900005471B1 KR 900005471 B1 KR900005471 B1 KR 900005471B1 KR 1019840000692 A KR1019840000692 A KR 1019840000692A KR 840000692 A KR840000692 A KR 840000692A KR 900005471 B1 KR900005471 B1 KR 900005471B1
Authority
KR
South Korea
Prior art keywords
oxazine
benzoxepino
hexahydro
hydrogen
trans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019840000692A
Other languages
English (en)
Korean (ko)
Other versions
KR840007729A (ko
Inventor
프리드만 쥴즈
씨.데이지 리차드
Original Assignee
메렐 다우 파마슈티칼스 인코포레이티드
그레이 디. 스트리트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 메렐 다우 파마슈티칼스 인코포레이티드, 그레이 디. 스트리트 filed Critical 메렐 다우 파마슈티칼스 인코포레이티드
Publication of KR840007729A publication Critical patent/KR840007729A/ko
Application granted granted Critical
Publication of KR900005471B1 publication Critical patent/KR900005471B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019840000692A 1983-02-15 1984-02-14 2H-[1]벤즈옥세피노[5,4-b]-1,4-옥사진 유도체 및 이의 제조방법 Expired KR900005471B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US46640783A 1983-02-15 1983-02-15
US466407 1983-02-15
US56275983A 1983-12-21 1983-12-21
US562759 1983-12-21

Publications (2)

Publication Number Publication Date
KR840007729A KR840007729A (ko) 1984-12-10
KR900005471B1 true KR900005471B1 (ko) 1990-07-30

Family

ID=27041648

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840000692A Expired KR900005471B1 (ko) 1983-02-15 1984-02-14 2H-[1]벤즈옥세피노[5,4-b]-1,4-옥사진 유도체 및 이의 제조방법

Country Status (14)

Country Link
EP (1) EP0116373B1 (https=)
KR (1) KR900005471B1 (https=)
AU (1) AU561700B2 (https=)
CA (1) CA1236833A (https=)
DE (1) DE3463142D1 (https=)
DK (1) DK158986C (https=)
ES (1) ES8600301A1 (https=)
GR (1) GR81510B (https=)
IE (1) IE56788B1 (https=)
IL (1) IL70941A (https=)
NO (1) NO167571C (https=)
NZ (1) NZ207110A (https=)
PH (1) PH22343A (https=)
PT (1) PT78109B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE939614C (de) * 1949-02-26 1956-02-23 Ernst Rodenhaeuser Kolbendichtung fuer Kolbenfuellhalter
US4766212A (en) * 1983-02-15 1988-08-23 Merrell Dow Pharmaceuticals Inc. 2H-[1]benzoxepino[5,4-b]-1,4-oxazine derivatives
NZ207111A (en) * 1983-02-15 1986-07-11 Merrell Dow Pharma (4a,11b)-3,4,4a,5,6,11b-hexahydro-2h-(1)benzoxepino(5,4-b)-1,4 oxazine derivatives and pharmaceutical compositions
FR2698873B1 (fr) * 1992-12-07 1995-02-24 Lipha Benzocycloheptènes, benzoxépines et benzothiépines activateurs des canaux potassiques, procédé de préparation, composition pharmaceutique les contenant.
CA2800219C (en) 2010-05-21 2019-03-12 Research Triangle Institute 1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
JP2013526583A (ja) 2010-05-21 2013-06-24 リサーチ・トライアングル・インスティチュート フェニルモルホリンおよびその類似体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1593760A1 (de) * 1967-02-01 1972-06-08 Boehringer Sohn Ingelheim Verfahren zur Herstellung neuer Benz-epinderivate

Also Published As

Publication number Publication date
IE840334L (en) 1984-08-15
DK66284D0 (da) 1984-02-14
EP0116373A1 (en) 1984-08-22
GR81510B (https=) 1984-12-11
NO167571B (no) 1991-08-12
NO840534L (no) 1984-08-16
ES529720A0 (es) 1985-10-01
IE56788B1 (en) 1991-12-18
AU2454284A (en) 1984-08-23
NO167571C (no) 1991-11-20
PT78109A (en) 1984-03-01
DE3463142D1 (de) 1987-05-21
DK158986B (da) 1990-08-13
IL70941A0 (en) 1984-05-31
AU561700B2 (en) 1987-05-14
KR840007729A (ko) 1984-12-10
NZ207110A (en) 1986-05-09
DK66284A (da) 1984-08-16
CA1236833A (en) 1988-05-17
PT78109B (en) 1986-05-20
PH22343A (en) 1988-08-12
EP0116373B1 (en) 1987-04-15
ES8600301A1 (es) 1985-10-01
DK158986C (da) 1991-01-07
IL70941A (en) 1987-12-31

Similar Documents

Publication Publication Date Title
CA1101430A (en) Derivatives of 4-amino 5-alkylsulphonyl ortho- anisamides, methods of preparing them
JP3205343B2 (ja) ジアリールジアミン誘導体およびそれらのデルタオピオイド（アント）−アゴニストとしての使用
PL112442B1 (en) Process for preparing novel ethers of hydroxy-benzodiheterocyclic compounds
EP1373219A1 (fr) Thiohydantoines et leur utilisation dans le traitement du diabete
AU3108097A (en) 4-phenylpiperidine compounds
FR2471968A1 (fr) Ethers basiques, leur procede de preparation et compositions pharmaceutiques les contenant
FR2674849A1 (fr) Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique.
KR900005471B1 (ko) 2H-[1]벤즈옥세피노[5,4-b]-1,4-옥사진 유도체 및 이의 제조방법
CA1125657A (en) Derivatives of 1,2,3,3a,8,8a-hexadydropyrrolo ¬2,3-b| indole
EP0179855B1 (en) Dopamine agonists
JPS60174783A (ja) 新規８α‐アシルアミノエルゴリン類
IE65639B1 (en) 4,5,6,7-Tetrahydrobenzimidazole derivatives and their preparation
KR100382998B1 (ko) 6-메톡시-1h-벤조트리아졸-5-카르복사미드유도체,그제조방법및그것을함유하는의약조성물
SK281980B6 (sk) Kryštallický (+)l-hydrogenvínan, spôsob jeho prípravy, farmaceutický prostriedok s jeho obsahom a jeho použitie
JPH03120271A (ja) 抗虚血活性を有するフェニルアルキルアミン誘導体
KR910003711B1 (ko) 2-(n-피롤리디노)-3-이소부톡시-n-치환된 페닐-n-벤질-프로필아민의 제조방법
CA1137489A (en) Derivatives of 1,2,3,3a,8,8a-hexadydropyrrolo (2,3-b) indole
CH628885A5 (en) Piperidine derivative
CA2040489C (en) 4-¬3-(4-oxothiazoldinyl)|butynylamines, a process for their preparation and their use as medicaments
EP0641789B1 (en) Benzothiadiazine derivative
CH665842A5 (fr) Derives de la pyridine, procede pour leur preparation et compositions therapeutiques les contenant.
RU2033414C1 (ru) Производные 4,5,6,7-тетрагидробензимидазола
EP0116372B1 (en) 2h-(1) benzoxepino (5,4-b)-1,4 oxazine derivatives
JPH0370711B2 (https=)
FR2500823A1 (fr) 1-aminoalkyl-1, 2, 3, 4-tetrahydroanphtalenes mono- ou disubstitues utiles notamment comme adrenergiques et medicaments les contenant

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

G160 Decision to publish patent application
PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 6

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 7

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 8

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 9

FPAY Annual fee payment

Payment date: 19990630

Year of fee payment: 10

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 10

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20000731

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20000731