KR900002073A - 녹을수 있게 함침된 시약을 갖는 운반체 매트릭스 - Google Patents

녹을수 있게 함침된 시약을 갖는 운반체 매트릭스 Download PDF

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KR900002073A
KR900002073A KR1019890010996A KR890010996A KR900002073A KR 900002073 A KR900002073 A KR 900002073A KR 1019890010996 A KR1019890010996 A KR 1019890010996A KR 890010996 A KR890010996 A KR 890010996A KR 900002073 A KR900002073 A KR 900002073A
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carrier matrix
glass
polyvinyl alcohol
coated
reagent
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KR1019890010996A
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KR920000258B1 (ko
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윌크 한스-에리히
만골드 디터
레르히 롤프
스테인비스 요하힘
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다움
뵈링거 만하임 게엠베하
포우퀘트
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/08—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer
    • C12N11/082—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a synthetic polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • C12N11/084—Polymers containing vinyl alcohol units
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81—Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812—Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815—Carrier is a synthetic polymer

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  • Health & Medical Sciences (AREA)
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  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
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  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
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Abstract

내용 없음

Description

녹을수 있게 함침된 시약을 갖는 운반체 매트릭스
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명에 따른 운반체 매트릭스를 함유하는 시험장치,
제2도는 본 발명에 따른 운반체 매트릭스를 함유하는 다른 시험장치,
제3도는 본 발명에 따른 운반체 매트릭스를 함유하는 시험장치의 사용으로 얻은 보정곡선.

Claims (15)

  1. 운반체 매트릭스가 폴리비닐 알코올-피복된 유리로 구성되는 녹을수 있게 함침된 시약을 갖는 운반체 매트릭스.
  2. 제1항에 있어서, 유리가 섬유형태로 존재함을 특징으로 하는 운반체 매트릭스.
  3. 제2항에 있어서, 유리섬유가 플리스로서 작용함을 특징으로 하는 운반체 매트릭스.
  4. 상기 항중 어느 한 항에 있어서, 유리가 0.5 내지 20중량%의 폴리비닐 알코올로 피복됨을 특징으로 하는 운반체 매트릭스.
  5. 제4항에 있어서, 유리가 1 내지 10중량%의 폴리비닐 알코올로 피복됨을 특징으로 하는 운반체 매트릭스.
  6. 상기 항중 어느 한 항에 있어서, 시약이 단백질을 함유하는 운반체 매트릭스.
  7. 상기 항중 어느 한 항에 있어서, 시약이 β-갈락토시다제를 함유하는 운반체 매트릭스.
  8. 실질적으로 상기 설명하고 예시한 바와같은 제1항에 따른 운반체 매트릭스.
  9. 유리가 폴리비닐 알코올로 피복되고, 피복된 유리가 시약으로 함침되고, 임의로 건조함을 특징으로 하는 제1항에 따른 운반체 매트릭스의 제조방법.
  10. 유리섬유가 폴리비닐 알코올의 부가와 더불어 과량의 물에 슬러리화되고, 페이퍼 제조에 유용한 방법에 따라 여기에 층을 형성하고, 증가된 온도에서 건조시키고, 층을 시약용액으로 함침시키고, 임으로 건조시킴을 특징으로 하는 제2 또는 제3항에 따른 운반체 매트릭스의 제조방법.
  11. 실질적으로 상기 설명하고, 예시한 바와같은 제1항에 따른 운반체 매트릭스의 제조방법.
  12. 제10항 또는 11항에 따른 방법에 의해 제조된 제1항에 따른 운반체 매트릭스.
  13. 녹을수 있게 함침된 시약을 위한 운반체로서 폴리비닐 알코올-피복된 유리의 사용.
  14. 효소학적 및/또는 면역학적 활성물질이 시약으로서 사용함을 특징으로 하는 제13항에 따른 폴리비닐 알코올-피복된 유리의 사용.
  15. 시험장치에 제1항에 따른 운반체 매트릭스의 사용 및 시료성분들의 결정방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019890010996A 1988-07-30 1989-07-31 녹을 수 있게 함침된 시약을 갖는 운반체 매트릭스, 그의 제조방법 및 사용방법 KR920000258B1 (ko)

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DEP38260557 1988-07-30
DE3826055A DE3826055A1 (de) 1988-07-30 1988-07-30 Mit reagenz abloesbar impraegnierte traegermatrix
DEP3826055.7 1988-07-30

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KR920000258B1 KR920000258B1 (ko) 1992-01-10

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US (1) US5403706A (ko)
EP (1) EP0353570B1 (ko)
JP (1) JPH0726961B2 (ko)
KR (1) KR920000258B1 (ko)
AT (1) ATE111605T1 (ko)
AU (1) AU616782B2 (ko)
CA (1) CA1334181C (ko)
DD (1) DD284088A5 (ko)
DE (2) DE3826055A1 (ko)
ES (1) ES2063790T3 (ko)

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DE3826055A1 (de) 1990-02-01
JPH0726961B2 (ja) 1995-03-29
EP0353570A2 (de) 1990-02-07
ES2063790T3 (es) 1995-01-16
EP0353570A3 (de) 1991-01-02
AU616782B2 (en) 1991-11-07
KR920000258B1 (ko) 1992-01-10
EP0353570B1 (de) 1994-09-14
DE58908351D1 (de) 1994-10-20
AU3882689A (en) 1990-02-01
JPH0278935A (ja) 1990-03-19
CA1334181C (en) 1995-01-31
DD284088A5 (de) 1990-10-31
ATE111605T1 (de) 1994-09-15
US5403706A (en) 1995-04-04

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