KR890700347A - 인터루킨-i활성의 억제 방법 - Google Patents
인터루킨-i활성의 억제 방법Info
- Publication number
- KR890700347A KR890700347A KR1019880701056A KR880701056A KR890700347A KR 890700347 A KR890700347 A KR 890700347A KR 1019880701056 A KR1019880701056 A KR 1019880701056A KR 880701056 A KR880701056 A KR 880701056A KR 890700347 A KR890700347 A KR 890700347A
- Authority
- KR
- South Korea
- Prior art keywords
- activity
- inhibiting interleukin
- interleukin
- inhibiting
- alleviation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94790586A | 1986-12-31 | 1986-12-31 | |
US947,905 | 1986-12-31 | ||
PCT/US1987/003479 WO1988004928A1 (en) | 1986-12-31 | 1987-12-28 | Method of inhibiting interleukin-1 activity |
Publications (2)
Publication Number | Publication Date |
---|---|
KR890700347A true KR890700347A (ko) | 1989-04-24 |
KR960015726B1 KR960015726B1 (ko) | 1996-11-20 |
Family
ID=25486973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880701056A KR960015726B1 (ko) | 1986-12-31 | 1987-12-28 | 인터루킨-ⅰ활성의 억제방법 |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0279079B1 (ko) |
JP (1) | JP2507012B2 (ko) |
KR (1) | KR960015726B1 (ko) |
AT (1) | ATE151290T1 (ko) |
AU (1) | AU668982B2 (ko) |
CA (1) | CA1313137C (ko) |
DE (1) | DE3752048T2 (ko) |
DK (1) | DK482088A (ko) |
ES (1) | ES2103255T3 (ko) |
GR (1) | GR3024054T3 (ko) |
IE (1) | IE873554L (ko) |
IL (7) | IL100536A (ko) |
WO (1) | WO1988004928A1 (ko) |
ZA (1) | ZA879754B (ko) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5196429A (en) * | 1986-12-31 | 1993-03-23 | Hoechst-Roussel Pharmaceuticals Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
US5196430A (en) * | 1986-12-31 | 1993-03-23 | Hoechst-Roussel Pharmaceuticals Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
US4965271A (en) * | 1986-12-31 | 1990-10-23 | Hoechst Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
US5272153A (en) * | 1986-12-31 | 1993-12-21 | Hoechst-Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
JPH04506215A (ja) * | 1989-06-13 | 1992-10-29 | スミスクライン・ビーチャム・コーポレイション | モノカイン活性干渉 |
DD298051A5 (de) * | 1989-08-16 | 1992-02-06 | ��@���������@�������k�� | Verfahren zur herstellung eines therapeutischen agens zur behandlung von verdauungskrankheiten |
EP0493682A3 (en) * | 1990-11-30 | 1992-11-19 | Hoechst-Roussel Pharmaceuticals Incorporated | Use of xanthines for the preparation of a medicament effective for inhibiting the effects of allograft reaction in humans |
EP0490181A1 (en) * | 1990-11-30 | 1992-06-17 | Hoechst-Roussel Pharmaceuticals Incorporated | Use of xanthines for preparation of a medicament having immunosuppressing activity |
US6420374B1 (en) | 1990-11-30 | 2002-07-16 | Fred Hutchinson Cancer Research Center | Use of xanthines as immunosuppressants and to inhibit allograft reactions |
WO1992021344A2 (en) * | 1991-05-24 | 1992-12-10 | Fred Hutchinson Cancer Research Center | Modulation of cellular response to external stimuli |
JPH05194233A (ja) * | 1991-06-10 | 1993-08-03 | Hoechst Roussel Pharmaceut Inc | マイクロペレットおよびそれらの製造方法 |
WO1993003728A1 (en) * | 1991-08-27 | 1993-03-04 | Temple University Of The Commonwealth System Of | Xanthine suppression of antigen activation of t- or b-cells |
ES2173871T3 (es) * | 1991-10-31 | 2002-11-01 | Univ Manchester | Tratamiento de condiciones neurologicas por un compuesto inhibidor de la interleukina-1. |
WO1996005836A2 (en) * | 1994-08-25 | 1996-02-29 | Medical University Of South Carolina | Methods of treating cold symptoms using pentoxifylline |
US5856330A (en) * | 1996-07-31 | 1999-01-05 | Hoechst Aktiengesellschaft | Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin |
US5981536A (en) * | 1996-07-31 | 1999-11-09 | Hoechst Aktiengesellschaft | Use of xanthine derivatives for the modulation of apoptosis |
JP3830115B2 (ja) * | 1997-10-06 | 2006-10-04 | シャープ株式会社 | 液晶表示素子 |
TW561297B (en) * | 1997-11-25 | 2003-11-11 | Toshiba Corp | Electrode wiring board subjected to counter measure against static electricity and display device using the same |
JP3019053B2 (ja) * | 1997-12-25 | 2000-03-13 | 日本電気株式会社 | 液晶表示装置及びその製造方法 |
BRPI0908107A2 (pt) | 2008-02-29 | 2019-09-24 | Concert Pharmaceuticals Inc | composto derivado de xantina substituída, composição farmacêutica que compreende esse composto, métodos de tratamento de uma enfermidade ou condição em um paciente com necessidade do mesmo, método de tratamento de enfermidade crônica dos rins, do fígado, relacionada com diabetes e de claudicação intermitente |
US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
CA2771331A1 (en) | 2009-09-02 | 2011-03-10 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
WO2012031138A2 (en) | 2010-09-01 | 2012-03-08 | Concert Pharmaceuticals, Inc. | Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purine-2,6(3h,7h)dione |
WO2013013052A1 (en) | 2011-07-19 | 2013-01-24 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
WO2013155465A1 (en) | 2012-04-13 | 2013-10-17 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
WO2013159006A1 (en) | 2012-04-20 | 2013-10-24 | Concert Pharmaceuticals, Inc. | Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2967632D1 (en) * | 1978-04-22 | 1986-12-04 | Beecham Wuelfing Gmbh & Co Kg | Use of a xanthine derivate in the manufacture of a medicament |
US4567183A (en) * | 1983-03-11 | 1986-01-28 | Analgesic Associates | Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same |
US4636507A (en) * | 1984-04-30 | 1987-01-13 | Hoechst-Roussel Pharmaceuticals Inc. | Host defense mechanism enhancement |
GB8418430D0 (en) * | 1984-07-19 | 1984-08-22 | Beecham Wuelfing Gmbh & Co Kg | Treatment |
-
1987
- 1987-12-23 IL IL10053687A patent/IL100536A/en not_active IP Right Cessation
- 1987-12-23 IL IL10685987A patent/IL106859A/en not_active IP Right Cessation
- 1987-12-23 IL IL8493487A patent/IL84934A/en not_active IP Right Cessation
- 1987-12-23 IL IL10053387A patent/IL100533A/en not_active IP Right Cessation
- 1987-12-23 IL IL10053587A patent/IL100535A/en not_active IP Right Cessation
- 1987-12-23 IL IL10686187A patent/IL106861A/xx not_active IP Right Cessation
- 1987-12-23 IL IL10685487A patent/IL106854A/en not_active IP Right Cessation
- 1987-12-28 JP JP63501103A patent/JP2507012B2/ja not_active Expired - Lifetime
- 1987-12-28 WO PCT/US1987/003479 patent/WO1988004928A1/en unknown
- 1987-12-28 KR KR1019880701056A patent/KR960015726B1/ko not_active IP Right Cessation
- 1987-12-30 AT AT87119377T patent/ATE151290T1/de not_active IP Right Cessation
- 1987-12-30 IE IE873554A patent/IE873554L/xx unknown
- 1987-12-30 DE DE3752048T patent/DE3752048T2/de not_active Expired - Fee Related
- 1987-12-30 EP EP87119377A patent/EP0279079B1/en not_active Expired - Lifetime
- 1987-12-30 CA CA000555613A patent/CA1313137C/en not_active Expired - Fee Related
- 1987-12-30 ES ES87119377T patent/ES2103255T3/es not_active Expired - Lifetime
- 1987-12-30 ZA ZA879754A patent/ZA879754B/xx unknown
-
1988
- 1988-08-30 DK DK482088A patent/DK482088A/da not_active Application Discontinuation
-
1993
- 1993-08-27 AU AU46027/93A patent/AU668982B2/en not_active Ceased
-
1997
- 1997-07-09 GR GR970401709T patent/GR3024054T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU4602793A (en) | 1993-11-18 |
EP0279079A2 (en) | 1988-08-24 |
ATE151290T1 (de) | 1997-04-15 |
GR3024054T3 (en) | 1997-10-31 |
DE3752048T2 (de) | 1997-10-02 |
IE873554L (en) | 1988-06-30 |
DK482088D0 (da) | 1988-08-30 |
DK482088A (da) | 1988-10-28 |
JPH02501829A (ja) | 1990-06-21 |
IL100533A (en) | 1994-05-30 |
JP2507012B2 (ja) | 1996-06-12 |
DE3752048D1 (de) | 1997-05-15 |
CA1313137C (en) | 1993-01-26 |
AU668982B2 (en) | 1996-05-23 |
IL100535A (en) | 1994-05-30 |
EP0279079A3 (en) | 1990-06-13 |
AU637542B2 (en) | 1993-05-27 |
WO1988004928A1 (en) | 1988-07-14 |
ES2103255T3 (es) | 1997-09-16 |
IL106859A (en) | 1996-10-16 |
EP0279079B1 (en) | 1997-04-09 |
IL106861A (en) | 1997-02-18 |
AU1150588A (en) | 1988-07-27 |
IL106854A (en) | 1996-05-14 |
AU619732B2 (en) | 1992-02-06 |
IL100536A (en) | 1994-05-30 |
AU1291892A (en) | 1992-05-14 |
IL84934A (en) | 1994-08-26 |
KR960015726B1 (ko) | 1996-11-20 |
ZA879754B (en) | 1989-07-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
KR890700347A (ko) | 인터루킨-i활성의 억제 방법 | |
IT1177344B (it) | Impianto per la produzione automatica di lenti organiche | |
TR23030A (tr) | Asillendirilmis diketonik bilesiklerin ueretilmesine mahsus usul | |
IT8320709A0 (it) | Composto per il trattamento della psoriasi. | |
DE3855956T2 (de) | Verwendung einer Triglyceridverbindung als Hämolysishemmer | |
IT1194756B (it) | Assieme di valvola di ritegno perfezionata | |
DK377687D0 (da) | Triazol-fungicidpraeparater | |
IT8419329A1 (it) | Pomata oleosa avente un'eccellente attività anti-infiammatoria | |
DK165591C (da) | Flerumaettede fluorsubstituerede alkoholforbindelser | |
FI863525A (fi) | Anordning foer foerskjutning och positionering av en kopplad kedjedel i en dragkedja under kompletteringsarbeten. | |
IT8967178A0 (it) | Mandrino agganciabile per il con trollo di pozzi | |
IT8848523A0 (it) | Procedimento integrato per la fitodepurazione di acque reflue | |
DE3776613D1 (de) | Dopamin-beta-hydroxylase-inhibitoren. | |
ES536258A0 (es) | Procedimiento para la obtencion de un aditivo para la conservacion de cefalopodos | |
IT8148624A0 (it) | Procedimento per la purificazione di 2-mercaptobenzotiazolo | |
SE8605561D0 (sv) | Skrepsil for takavvattningsutlopp | |
LT2310B (lt) | Medziagos su reguliuojamu aktyviojo junginio islaisvinimu gavimo budas | |
IT8334956V0 (it) | Attrezzo per la posatura dei giardini delle scale, anche con alzata superiormente inclinata all'indietro | |
IT8531622V0 (it) | Valvola indicastop trafilamento olio | |
IT207870Z2 (it) | Dado di tipo perfezionato | |
IT8622389A0 (it) | Procedimento per la preparazione di composti ad attivita' anti ulcera | |
BR6500265U (pt) | Furadeira hidraulica automatica | |
KR880001058U (ko) | 가습기의 앙금 방지 장치 | |
KR870010429U (ko) | 표층수 취수용 사이펀 | |
LV5359A3 (lv) | Panemiens nevelamu augu apkarosanai |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A201 | Request for examination | ||
E902 | Notification of reason for refusal | ||
E601 | Decision to refuse application | ||
J2X1 | Appeal (before the patent court) |
Free format text: APPEAL AGAINST DECISION TO DECLINE REFUSAL |
|
G160 | Decision to publish patent application | ||
E701 | Decision to grant or registration of patent right | ||
GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |