KR890002667A - 비-금속 콜로이드성 입자 면역검정 - Google Patents

비-금속 콜로이드성 입자 면역검정 Download PDF

Info

Publication number
KR890002667A
KR890002667A KR1019880008553A KR880008553A KR890002667A KR 890002667 A KR890002667 A KR 890002667A KR 1019880008553 A KR1019880008553 A KR 1019880008553A KR 880008553 A KR880008553 A KR 880008553A KR 890002667 A KR890002667 A KR 890002667A
Authority
KR
South Korea
Prior art keywords
analyte
sample
colloidal
selenium
amount
Prior art date
Application number
KR1019880008553A
Other languages
English (en)
Inventor
안토니 요스트 데이비드
카로 러셀 존
양 희정
Original Assignee
죠셉 엠.베르닉
애보트 래보러 토리즈
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 죠셉 엠.베르닉, 애보트 래보러 토리즈 filed Critical 죠셉 엠.베르닉
Publication of KR890002667A publication Critical patent/KR890002667A/ko

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

내용 없음

Description

비-금속 콜로이드성 입자 면역검정
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 방법을 시용하여 분석한 hCG 샘플에 대한 여러 파장에서의 광학밀도 측정의 도식을 나타낸다. 제2도는 본 발명의 방법을 사용하여 hCG의 분광광도계 및 형광 밀도 측정의 비교용 도식을 나타낸다.

Claims (10)

  1. 샘플을 분석 대상을 특이적으로 인지할 수 있는 결합 성분이 결합되어 있는 콜로이드성 비-금속 입자를 포함하는 비-금속 표지된 성분과 접촉시킨 다음, 샘플중 분석 대상의 양의 측정으로서 분석대상/콜로이드성 비-금속 입자 착물의 존재 또는 양을 측정하는 단계를 포함하는, 샘플중 분석대상의 존재 또는 양을 측정하는 방법.
  2. 제1항에 있어서, 상기 콜로이드성 비-금속 입자가 황, 셀레늄 및 텔루륨으로 이루어진 그룹으로 부터 선택되는 방법.
  3. 제1항에 있어서, 상기 비-금속 입자에 결합되어 있는 결합 이성분이 항원, 합텐(haptem) 및 항체로 구성되는 부류로부터 선택되는 방법.
  4. 샘플과, 분석대상을 인지할 수 있는 결합 화합물이 결합되어 있는 콜로이드성 셀레늄 입자의 수성 분산액을 포함하는 셀레늄 표지된 성분과의 반응 혼합물을 생성하고, 샘플중 분석 대상의 양의 측정으로서 상기 반응 혼합물중 분석대상/셀레늄 표지된 성분의 응집 착물의 존재 또는 양을 광학적 특성의 변화를 측정함으로써 결정하는 단계를 포함하는, 샘플중 분석대상의 존재 또는 양을 측정하는 방법.
  5. 제4항에 있어서, 상기의 셀레늄 표지된 결합 성분이 셀레늄 표지된 항원, 합텐 및 항체로 구성된 부류로부터 선택되는 방법.
  6. 제1항 또는 4항에 있어서, 상기 콜로이드성 입자가 약 3mm 내지 약 450mm의 입자 크기를 갖는 방법.
  7. 콜로이드성 비-금속 입자 및 분석대상을 특이적으로 인지할 수 있는 결합 성분을 포함하는, 샘풀중 분석 대상의 측정에 유용한 조성물.
  8. 제7항에 있어서, 상기 콜로이드성 비-금속 입자가 황, 셀레늄 또는 텔루륨인 조성물.
  9. 제7항에 있어서, 상기 결합 성분이 항원, 합텐 또는 항체인 조성물.
  10. 제7항에 있어서, 상기 콜로이드성 비-금속 입자가 약 3mm 내지 약 450mm의 입자 크기를 갖는 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880008553A 1987-07-09 1988-07-09 비-금속 콜로이드성 입자 면역검정 KR890002667A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/072,084 US4954452A (en) 1987-07-09 1987-07-09 Non-metal colloidal particle immunoassay
US072,084 1987-07-09

Publications (1)

Publication Number Publication Date
KR890002667A true KR890002667A (ko) 1989-04-11

Family

ID=22105464

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880008553A KR890002667A (ko) 1987-07-09 1988-07-09 비-금속 콜로이드성 입자 면역검정

Country Status (9)

Country Link
US (1) US4954452A (ko)
EP (1) EP0298368B1 (ko)
JP (1) JP2708475B2 (ko)
KR (1) KR890002667A (ko)
AT (1) ATE114191T1 (ko)
AU (1) AU608866B2 (ko)
CA (1) CA1331560C (ko)
DE (1) DE3852117T2 (ko)
ES (1) ES2066774T3 (ko)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
ES2184734T3 (es) 1987-04-27 2003-04-16 Inverness Medical Switzerland Dispositivo de prueba analitica para realizar ensayos de union especifica.
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
NL8702769A (nl) * 1987-11-19 1989-06-16 Holland Biotechnology Werkwijze voor het bepalen in een testmonster van componenten van de reactie tussen een specifiek bindend eiwit en de bijbehorende bindbare stof onder toepassing van ten minste een gemerkte component, werkwijze voor het bereiden van de gemerkte component, en testkit voor de bepaling van immunocomponenten.
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5348891A (en) * 1988-11-15 1994-09-20 H.B.T. Holland Biotechnology Method for an increased visualization of the reaction product of a specifically binding substance and a corresponding bindable substance and test kit therefor
US5294370A (en) * 1988-11-15 1994-03-15 Hbt Holland Biotechnology B.V. Selenium or tellurium elemental hydrosols and their preparation
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5075078A (en) * 1989-10-05 1991-12-24 Abbott Laboratories Self-performing immunochromatographic device
US5252496A (en) * 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
KR910014706A (ko) * 1990-01-10 1991-08-31 원본미기재 세척이 필요없는 개량된 이뮤노어세이(immunoassay)장치
US5518887A (en) * 1992-03-30 1996-05-21 Abbott Laboratories Immunoassays empolying generic anti-hapten antibodies and materials for use therein
US5770389A (en) * 1993-09-27 1998-06-23 Abbott Laboratories Apparatus and method for determining the quanity of an analyte in a biological sample by means of transmission photometry
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
US5795784A (en) 1996-09-19 1998-08-18 Abbott Laboratories Method of performing a process for determining an item of interest in a sample
US5856194A (en) 1996-09-19 1999-01-05 Abbott Laboratories Method for determination of item of interest in a sample
US6103536A (en) * 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
US20020004246A1 (en) * 2000-02-07 2002-01-10 Daniels Robert H. Immunochromatographic methods for detecting an analyte in a sample which employ semiconductor nanocrystals as detectable labels
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
AU2001270078A1 (en) * 2000-06-23 2002-01-08 Minerva Biotechnologies Corporation Tandem signaling assay
DE10035706C2 (de) * 2000-07-21 2002-11-07 Brahms Ag Verfahren zur selektiven Bestimmung von blockierenden Autoantikörpern gegen den TSH-Rezeptor
US7300633B2 (en) 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
US7393696B2 (en) * 2001-09-28 2008-07-01 Aspenbio Pharma, Inc. Bovine pregnancy test
JP4739755B2 (ja) * 2002-10-11 2011-08-03 ゼットビーエックス コーポレーション 診断装置
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
US7638093B2 (en) * 2004-01-28 2009-12-29 Dnt Scientific Research, Llc Interrupted flow rapid confirmatory immunological testing device and method
US7465587B2 (en) * 2004-12-03 2008-12-16 Genzyme Corporation Diagnostic assay device
US20060292700A1 (en) * 2005-06-22 2006-12-28 Naishu Wang Diffused interrupted lateral flow immunoassay device and method
US7888043B2 (en) 2005-11-18 2011-02-15 The United States Of America As Represented By The Department Of Health And Human Services, Centers For Disease Control And Prevention Modified cardiolipin and uses therefor
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
US20080138842A1 (en) * 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
US7919331B2 (en) * 2006-12-21 2011-04-05 Silver Lake Research Corporation Chromatographic test strips for one or more analytes
CN101607995B (zh) 2007-06-15 2013-05-01 厦门大学 特异性结合h5亚型禽流感病毒血凝素蛋白的单克隆抗体或其结合活性片段及其用途
AU2010241706B2 (en) 2009-04-29 2015-07-09 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. ERG monoclonal antibodies
WO2010132447A2 (en) 2009-05-11 2010-11-18 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
WO2012012500A1 (en) 2010-07-20 2012-01-26 Nurx Pharmaceuticals, Inc. Optical reader systems and lateral flow assays
WO2012012499A1 (en) 2010-07-20 2012-01-26 Nurx Pharmaceuticals, Inc. Optical reader system
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US8703439B1 (en) 2011-01-31 2014-04-22 Linda Lester Point of care iodine sensor
US9404923B2 (en) 2012-02-07 2016-08-02 Intuitive Biosciences, Inc. Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
DE102012013888A1 (de) 2012-07-09 2014-05-22 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
DE202012012084U1 (de) 2012-07-09 2013-04-15 Schebo Biotech Ag Testkit (Kombi-Schnelltest) zum synchronen Nachweis von Biomarkern im Stuhl zur Erkennung pathologischer Veränderungen im Gastrointestinaltrakt, insbesondere im Darm
WO2014152656A1 (en) 2013-03-14 2014-09-25 Cheng Kasing Test strip housing system
US10160797B2 (en) 2013-03-15 2018-12-25 Sanofi Pasteur Biologics, Llc Antibodies against Clostridium difficile toxins and methods of using the same
US20180011088A1 (en) 2015-01-29 2018-01-11 Neogen Corporation Methods for Immuno Chromatographic Assay Desensitization
CA3001918C (en) 2015-10-15 2023-08-22 Inbios International, Inc. Multiplexed lateral flow assay systems and methods for their use
EP3425393B1 (en) 2016-02-29 2022-12-21 FUJIFILM Corporation Kit for determining quantity of substance to be assayed in biological sample
CN105724428B (zh) * 2016-03-02 2017-02-22 广东省生态环境与土壤研究所（广东省土壤科学博物馆） 一种精准调控水稻镉吸收转运相关基因表达的叶面阻隔剂与应用
JP2023547188A (ja) 2020-10-27 2023-11-09 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 住血吸虫感染症の検出のためのタンパク質
NL2032668B1 (en) 2022-08-02 2024-02-07 Academisch Ziekenhuis Leiden Means for detecting schistosoma infection

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4022876A (en) * 1973-06-21 1977-05-10 Stanford Research Institute Mass spectrometric immunoassay
US4122030A (en) * 1977-09-19 1978-10-24 Xerox Corporation Formation of colloidal dispersions of selenium by the locus control method
NL7807532A (nl) * 1978-07-13 1980-01-15 Akzo Nv Metaal-immunotest.
NL8000173A (nl) * 1980-01-11 1981-08-03 Akzo Nv Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen.
US4341757A (en) * 1980-09-02 1982-07-27 Nutrition 21 Stable isotopic immunoassay method employing non-radioactive selenium label
US4645619A (en) * 1985-05-28 1987-02-24 Xerox Corporation Process for the preparation of colloidal dispersions of chalcogens and chalcogenide alloys
JPS62116263A (ja) * 1985-11-15 1987-05-27 Olympus Optical Co Ltd 直線偏光の多重散乱を用いる免疫反応の測定方法および装置
US4927749A (en) * 1986-04-09 1990-05-22 Jeanette Simpson Reagent for cell separation
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
NL8702769A (nl) * 1987-11-19 1989-06-16 Holland Biotechnology Werkwijze voor het bepalen in een testmonster van componenten van de reactie tussen een specifiek bindend eiwit en de bijbehorende bindbare stof onder toepassing van ten minste een gemerkte component, werkwijze voor het bereiden van de gemerkte component, en testkit voor de bepaling van immunocomponenten.

Also Published As

Publication number Publication date
JP2708475B2 (ja) 1998-02-04
EP0298368A3 (en) 1991-01-09
EP0298368B1 (en) 1994-11-17
AU1882688A (en) 1989-01-12
EP0298368A2 (en) 1989-01-11
DE3852117D1 (de) 1994-12-22
CA1331560C (en) 1994-08-23
DE3852117T2 (de) 1995-03-30
AU608866B2 (en) 1991-04-18
US4954452A (en) 1990-09-04
ATE114191T1 (de) 1994-12-15
JPS6435372A (en) 1989-02-06
ES2066774T3 (es) 1995-03-16

Similar Documents

Publication Publication Date Title
KR890002667A (ko) 비-금속 콜로이드성 입자 면역검정
CN106872420B (zh) 一种时间分辨荧光定量检测尿微量白蛋白的试剂盒及方法
AU667728B2 (en) Method for improving measurement precision in evanescent wave optical biosensor assays
CN110763834B (zh) 一种检测免疫标志物含量的方法、试剂和试剂盒
EP0399184A3 (en) Reagents, methods and kits for an amphetamine-class fluorescence polarization immunoassay
PT69900A (pt) Sol particle labelled immuno-assay
US6551788B1 (en) Particle-based ligand assay with extended dynamic range
KR960029789A (ko) 생체내 물질의 면역학적 분석용 키트 및 면역학적 분석 방법
AU2004227171B2 (en) Optical chemical sensing device with pyroelectric or piezoelectric transducer
EP0740156B1 (en) Immuno and enzyme assays based on surface second harmonic and sumfrequency generation
KR900003632A (ko) 특이적으로 결합가능한 물질의 정량방법
KR900002075A (ko) 특이적으로 결합가능한 물질의 정량 방법 및 시약
DK0381450T3 (da) Assay for basisk phosphatase fra knogler.
NO874140D0 (no) Immunometriske bestemmelsesfremgangsmaater.
KR950006462A (ko) 면역 분석 방법
KR870002456A (ko) Tsh의 측정방법
EP0380019A3 (en) Methadone fluorescence polarization immunoassay
CN116413445A (zh) 一种检测总甲状腺素含量的检测卡、试剂盒及其检测方法
JP2000258418A (ja) 免疫クロマトグラフィーを用いた測定方法およびそれに用いる検体分析用具
RU2789545C1 (ru) Способ высокочувствительного конкурентного иммунохроматографического анализа
CN212228955U (zh) 一种简易型检测装置
Hadžić et al. Immunosensors: Recent Advances and Applications
KR960018583A (ko) 면역 분석법
US20130052632A1 (en) Method for sensing a chemical
Pushkarev et al. Fouling-proof real-time optosensors for polyvalency-based characterization of circulating antibodies

Legal Events

Date Code Title Description
A201 Request for examination
E902 Notification of reason for refusal
E601 Decision to refuse application