KR890002667A - 비-금속 콜로이드성 입자 면역검정 - Google Patents

비-금속 콜로이드성 입자 면역검정 Download PDF

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KR890002667A
KR890002667A KR1019880008553A KR880008553A KR890002667A KR 890002667 A KR890002667 A KR 890002667A KR 1019880008553 A KR1019880008553 A KR 1019880008553A KR 880008553 A KR880008553 A KR 880008553A KR 890002667 A KR890002667 A KR 890002667A
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analyte
sample
colloidal
selenium
amount
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KR1019880008553A
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안토니 요스트 데이비드
카로 러셀 존
양 희정
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죠셉 엠.베르닉
애보트 래보러 토리즈
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Publication of KR890002667A publication Critical patent/KR890002667A/ko

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

내용 없음

Description

비-금속 콜로이드성 입자 면역검정
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 본 발명의 방법을 시용하여 분석한 hCG 샘플에 대한 여러 파장에서의 광학밀도 측정의 도식을 나타낸다. 제2도는 본 발명의 방법을 사용하여 hCG의 분광광도계 및 형광 밀도 측정의 비교용 도식을 나타낸다.

Claims (10)

  1. 샘플을 분석 대상을 특이적으로 인지할 수 있는 결합 성분이 결합되어 있는 콜로이드성 비-금속 입자를 포함하는 비-금속 표지된 성분과 접촉시킨 다음, 샘플중 분석 대상의 양의 측정으로서 분석대상/콜로이드성 비-금속 입자 착물의 존재 또는 양을 측정하는 단계를 포함하는, 샘플중 분석대상의 존재 또는 양을 측정하는 방법.
  2. 제1항에 있어서, 상기 콜로이드성 비-금속 입자가 황, 셀레늄 및 텔루륨으로 이루어진 그룹으로 부터 선택되는 방법.
  3. 제1항에 있어서, 상기 비-금속 입자에 결합되어 있는 결합 이성분이 항원, 합텐(haptem) 및 항체로 구성되는 부류로부터 선택되는 방법.
  4. 샘플과, 분석대상을 인지할 수 있는 결합 화합물이 결합되어 있는 콜로이드성 셀레늄 입자의 수성 분산액을 포함하는 셀레늄 표지된 성분과의 반응 혼합물을 생성하고, 샘플중 분석 대상의 양의 측정으로서 상기 반응 혼합물중 분석대상/셀레늄 표지된 성분의 응집 착물의 존재 또는 양을 광학적 특성의 변화를 측정함으로써 결정하는 단계를 포함하는, 샘플중 분석대상의 존재 또는 양을 측정하는 방법.
  5. 제4항에 있어서, 상기의 셀레늄 표지된 결합 성분이 셀레늄 표지된 항원, 합텐 및 항체로 구성된 부류로부터 선택되는 방법.
  6. 제1항 또는 4항에 있어서, 상기 콜로이드성 입자가 약 3mm 내지 약 450mm의 입자 크기를 갖는 방법.
  7. 콜로이드성 비-금속 입자 및 분석대상을 특이적으로 인지할 수 있는 결합 성분을 포함하는, 샘풀중 분석 대상의 측정에 유용한 조성물.
  8. 제7항에 있어서, 상기 콜로이드성 비-금속 입자가 황, 셀레늄 또는 텔루륨인 조성물.
  9. 제7항에 있어서, 상기 결합 성분이 항원, 합텐 또는 항체인 조성물.
  10. 제7항에 있어서, 상기 콜로이드성 비-금속 입자가 약 3mm 내지 약 450mm의 입자 크기를 갖는 조성물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880008553A 1987-07-09 1988-07-09 비-금속 콜로이드성 입자 면역검정 KR890002667A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US072,084 1987-07-09
US07/072,084 US4954452A (en) 1987-07-09 1987-07-09 Non-metal colloidal particle immunoassay

Publications (1)

Publication Number Publication Date
KR890002667A true KR890002667A (ko) 1989-04-11

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KR1019880008553A KR890002667A (ko) 1987-07-09 1988-07-09 비-금속 콜로이드성 입자 면역검정

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Country Link
US (1) US4954452A (ko)
EP (1) EP0298368B1 (ko)
JP (1) JP2708475B2 (ko)
KR (1) KR890002667A (ko)
AT (1) ATE114191T1 (ko)
AU (1) AU608866B2 (ko)
CA (1) CA1331560C (ko)
DE (1) DE3852117T2 (ko)
ES (1) ES2066774T3 (ko)

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Publication number Publication date
JPS6435372A (en) 1989-02-06
ATE114191T1 (de) 1994-12-15
ES2066774T3 (es) 1995-03-16
EP0298368A2 (en) 1989-01-11
EP0298368A3 (en) 1991-01-09
JP2708475B2 (ja) 1998-02-04
US4954452A (en) 1990-09-04
EP0298368B1 (en) 1994-11-17
DE3852117T2 (de) 1995-03-30
AU608866B2 (en) 1991-04-18
DE3852117D1 (de) 1994-12-22
AU1882688A (en) 1989-01-12
CA1331560C (en) 1994-08-23

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