KR880007481A - 아졸 유도체 - Google Patents
아졸 유도체 Download PDFInfo
- Publication number
- KR880007481A KR880007481A KR870013695A KR870013695A KR880007481A KR 880007481 A KR880007481 A KR 880007481A KR 870013695 A KR870013695 A KR 870013695A KR 870013695 A KR870013695 A KR 870013695A KR 880007481 A KR880007481 A KR 880007481A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- formula
- acid addition
- aryl
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000007980 azole derivatives Chemical class 0.000 title claims 2
- 150000001875 compounds Chemical class 0.000 claims 10
- 239000002253 acid Substances 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 125000001072 heteroaryl group Chemical group 0.000 claims 4
- 125000003118 aryl group Chemical group 0.000 claims 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 3
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 claims 2
- 229940122815 Aromatase inhibitor Drugs 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 239000003886 aromatase inhibitor Substances 0.000 claims 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical group C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 125000005842 heteroatom Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- -1 monosubstituted phenyl Chemical group 0.000 claims 1
- LONWTLLIALIPKY-UHFFFAOYSA-N n-[2,2-bis(4-chlorophenyl)-2-imidazol-1-ylethyl]-4-chlorobenzamide Chemical compound C1=CC(Cl)=CC=C1C(=O)NCC(N1C=NC=C1)(C=1C=CC(Cl)=CC=1)C1=CC=C(Cl)C=C1 LONWTLLIALIPKY-UHFFFAOYSA-N 0.000 claims 1
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000011593 sulfur Substances 0.000 claims 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP3641320.8 | 1986-12-03 | ||
| DE3641320 | 1986-12-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR880007481A true KR880007481A (ko) | 1988-08-27 |
Family
ID=6315380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR870013695A Ceased KR880007481A (ko) | 1986-12-03 | 1987-12-02 | 아졸 유도체 |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JPH0678318B2 (enExample) |
| KR (1) | KR880007481A (enExample) |
| AT (1) | AT395587B (enExample) |
| AU (1) | AU605522B2 (enExample) |
| BE (1) | BE1001235A4 (enExample) |
| CH (1) | CH677925A5 (enExample) |
| DK (1) | DK631287A (enExample) |
| ES (1) | ES2010235A6 (enExample) |
| FI (1) | FI875300A7 (enExample) |
| FR (1) | FR2607810B1 (enExample) |
| GB (1) | GB2199579B (enExample) |
| GR (1) | GR871897B (enExample) |
| HU (1) | HU198694B (enExample) |
| IL (1) | IL84665A (enExample) |
| IT (1) | IT1211944B (enExample) |
| LU (1) | LU87063A1 (enExample) |
| MY (1) | MY103004A (enExample) |
| NL (1) | NL8702897A (enExample) |
| NZ (1) | NZ222765A (enExample) |
| PH (1) | PH24666A (enExample) |
| PL (1) | PL151588B1 (enExample) |
| PT (1) | PT86255B (enExample) |
| SE (1) | SE8704792L (enExample) |
| ZA (1) | ZA879093B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8814277D0 (en) * | 1988-06-16 | 1988-07-20 | Glaxo Group Ltd | Chemical compounds |
| HU220863B1 (en) * | 1991-09-02 | 2002-06-29 | Yamanouchi Pharma Co Ltd | Triazolylated tertiary amines, process for producing them and pharmaceutical compositions containing them |
| GB9409882D0 (en) * | 1994-05-18 | 1994-07-06 | Sandoz Ltd | Organic compounds |
| GB0128415D0 (en) * | 2001-11-27 | 2002-01-16 | Univ Sheffield | Medicaments |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT382868B (de) * | 1983-03-11 | 1987-04-27 | Sandoz Ag | Verfahren zur herstellung neuer azolderivate und deren salze |
| JPH0625144B2 (ja) * | 1986-02-24 | 1994-04-06 | 四国化成工業株式会社 | 新規イミダゾール化合物及び該化合物の合成方法 |
-
1987
- 1987-11-26 CH CH4607/87A patent/CH677925A5/de not_active IP Right Cessation
- 1987-11-30 GB GB8727978A patent/GB2199579B/en not_active Expired - Lifetime
- 1987-12-01 PH PH36145A patent/PH24666A/en unknown
- 1987-12-01 AU AU81962/87A patent/AU605522B2/en not_active Ceased
- 1987-12-01 FI FI875300A patent/FI875300A7/fi not_active IP Right Cessation
- 1987-12-01 IL IL84665A patent/IL84665A/xx unknown
- 1987-12-01 NZ NZ222765A patent/NZ222765A/en unknown
- 1987-12-01 IT IT8748656A patent/IT1211944B/it active
- 1987-12-01 DK DK631287A patent/DK631287A/da not_active Application Discontinuation
- 1987-12-01 MY MYPI87003136A patent/MY103004A/en unknown
- 1987-12-01 SE SE8704792A patent/SE8704792L/xx not_active Application Discontinuation
- 1987-12-02 FR FR878716736A patent/FR2607810B1/fr not_active Expired
- 1987-12-02 BE BE8701375A patent/BE1001235A4/fr not_active IP Right Cessation
- 1987-12-02 AT AT0316887A patent/AT395587B/de not_active IP Right Cessation
- 1987-12-02 PL PL1987269180A patent/PL151588B1/pl unknown
- 1987-12-02 NL NL8702897A patent/NL8702897A/nl not_active Application Discontinuation
- 1987-12-02 HU HU875414A patent/HU198694B/hu unknown
- 1987-12-02 JP JP62305522A patent/JPH0678318B2/ja not_active Expired - Lifetime
- 1987-12-02 PT PT86255A patent/PT86255B/pt not_active IP Right Cessation
- 1987-12-02 KR KR870013695A patent/KR880007481A/ko not_active Ceased
- 1987-12-03 LU LU87063A patent/LU87063A1/fr unknown
- 1987-12-03 ES ES8703470A patent/ES2010235A6/es not_active Expired
- 1987-12-03 ZA ZA879093A patent/ZA879093B/xx unknown
- 1987-12-14 GR GR871897A patent/GR871897B/el unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19871202 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19921201 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19871202 Comment text: Patent Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19950724 Patent event code: PE09021S01D |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 19960104 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19950724 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |