KR880002002B1 - N-(1,3-디티올란-2-일리덴)아닐린 유도체 및 이의 제조방법 - Google Patents

N-(1,3-디티올란-2-일리덴)아닐린 유도체 및 이의 제조방법 Download PDF

Info

Publication number
KR880002002B1
KR880002002B1 KR1019830001498A KR830001498A KR880002002B1 KR 880002002 B1 KR880002002 B1 KR 880002002B1 KR 1019830001498 A KR1019830001498 A KR 1019830001498A KR 830001498 A KR830001498 A KR 830001498A KR 880002002 B1 KR880002002 B1 KR 880002002B1
Authority
KR
South Korea
Prior art keywords
ylidene
dithiolane
compound
carbon atoms
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR1019830001498A
Other languages
English (en)
Korean (ko)
Other versions
KR840004420A (ko
Inventor
린 해리슨 보이드
스테펜 도허티 니올
Original Assignee
메렐 다우 파마슈티칼스 인코포레이티드
메이나드 알.죤슨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 메렐 다우 파마슈티칼스 인코포레이티드, 메이나드 알.죤슨 filed Critical 메렐 다우 파마슈티칼스 인코포레이티드
Publication of KR840004420A publication Critical patent/KR840004420A/ko
Application granted granted Critical
Publication of KR880002002B1 publication Critical patent/KR880002002B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02—Five-membered rings
    • C07D339/06—Five-membered rings having the hetero atoms in positions 1 and 3, e.g. cyclic dithiocarbonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Secondary Cells (AREA)
  • Battery Electrode And Active Subsutance (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019830001498A 1982-04-12 1983-04-11 N-(1,3-디티올란-2-일리덴)아닐린 유도체 및 이의 제조방법 Expired KR880002002B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US367,510 1982-04-12
US06/367,510 US4435420A (en) 1982-04-12 1982-04-12 Anti-inflammatory agents and antiasthmatic agents

Publications (2)

Publication Number Publication Date
KR840004420A KR840004420A (ko) 1984-10-15
KR880002002B1 true KR880002002B1 (ko) 1988-10-11

Family

ID=23447478

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019830001498A Expired KR880002002B1 (ko) 1982-04-12 1983-04-11 N-(1,3-디티올란-2-일리덴)아닐린 유도체 및 이의 제조방법

Country Status (16)

Country Link
US (1) US4435420A (enExample)
EP (1) EP0100815B1 (enExample)
JP (1) JPS58188876A (enExample)
KR (1) KR880002002B1 (enExample)
AT (1) ATE16933T1 (enExample)
AU (1) AU556292B2 (enExample)
CA (1) CA1189518A (enExample)
DE (1) DE3361469D1 (enExample)
DK (1) DK159112C (enExample)
ES (2) ES8500261A1 (enExample)
GR (1) GR78825B (enExample)
IE (1) IE54476B1 (enExample)
IL (1) IL68321A0 (enExample)
NO (1) NO155241C (enExample)
NZ (1) NZ203832A (enExample)
ZA (1) ZA832447B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1510014A (fr) 1966-12-05 1968-01-19 Aquitaine Petrole Préparation de dithiolannes
FR1516855A (fr) 1966-12-20 1968-02-05 Aquitaine Petrole Fabrication d'imino-dithiolannes
US3914428A (en) * 1973-10-26 1975-10-21 American Cyanamid Co Method of using 2-arylimino-1,3-dithietane compounds as growth promotants
US4025532A (en) * 1974-10-31 1977-05-24 American Cyanamid Company 2-(O-Tolyl)imino-1,3-dithioles, a method for preparing the same, and their utilization as ixodicides
JPS5220589A (en) * 1975-08-08 1977-02-16 Kobe Steel Ltd Ship for operation of improving soft viscous ground
DE2537379A1 (de) 1975-08-22 1977-03-03 Bayer Ag Substituierte 2-phenylimino-1,3- dithiolane, verfahren zu ihrer herstellung sowie ihre verwendung als ektoparasitizide mittel
US4172941A (en) 1978-05-12 1979-10-30 Richardson-Merrell Inc. 7-[2-[ω-(1,3-Dithiolan-2-imino)substituted]-acetylamino]cephalosporanic acid derivatives
US4131683A (en) 1978-05-12 1978-12-26 Richardson-Merrell Inc. ω-(1,3-Dithiolan-2-imino) substituted acetic acids

Also Published As

Publication number Publication date
NO155241B (no) 1986-11-24
JPS58188876A (ja) 1983-11-04
DK159112C (da) 1991-02-11
DK159083A (da) 1983-10-13
JPH0474354B2 (enExample) 1992-11-26
CA1189518A (en) 1985-06-25
AU556292B2 (en) 1986-10-30
EP0100815B1 (en) 1985-12-11
ES521376A0 (es) 1984-11-01
IE830818L (en) 1983-10-12
GR78825B (enExample) 1984-10-02
ES533855A0 (es) 1985-12-16
NZ203832A (en) 1986-05-09
IL68321A0 (en) 1983-07-31
ES8602749A1 (es) 1985-12-16
US4435420A (en) 1984-03-06
NO155241C (no) 1987-03-04
AU1327783A (en) 1983-10-20
DE3361469D1 (en) 1986-01-23
IE54476B1 (en) 1989-10-25
KR840004420A (ko) 1984-10-15
DK159083D0 (da) 1983-04-11
NO831271L (no) 1983-10-13
ATE16933T1 (de) 1985-12-15
EP0100815A1 (en) 1984-02-22
ES8500261A1 (es) 1984-11-01
ZA832447B (en) 1983-12-28
DK159112B (da) 1990-09-03

Similar Documents

Publication Publication Date Title
CZ294963B6 (cs) 2-(3H)-Oxazolonové deriváty, způsob jejich přípravy, farmaceutické kompozice a jejich použití
JPS6013759A (ja) ピリジン誘導体
KR900004828B1 (ko) 페닐-나프티리딘의 제조방법
JPH0222271A (ja) 共役γ−オキシブテノライド化合物およびこれを有効成分とする抗潰瘍剤
US4435420A (en) Anti-inflammatory agents and antiasthmatic agents
PT91555B (pt) Processo de preparacao de derivados de dibenzo{2,3:6,7}-(oxepino ou tiepino){4,5-c}(piridina ou pirrol)e de composicoes farmaceuticas que os contem
CS256400B2 (cs) Způsob výroby nových pyridylmethyllsulfinylthieno(2.3-d)imi<lazolových derivátů
US4157340A (en) N,N'-[Bis(N-cyanoguanyl)]cystamine derivatives
KR910008183B1 (ko) 머캅토-아세트산 및 머캅토프로피온산 아미드 유도체의 제조방법
JPS5914037B2 (ja) イソキノリン誘導体、その製造方法およびそれを含有する医薬組成物
JPS60104084A (ja) 4H‐ベンゾ〔4,5〕シクロヘプタ〔1,2‐b〕チオフエン誘導体
HU181947B (en) Process for producing pyridyl-indol derivatives
FR2525221A1 (fr) Derives du furanne et sels d'addition de ces derives, leurs procedes de preparation et leurs applications en therapeutique
EP0119541A1 (en) Substituted 4,10-dihydro-10-oxothieno-benzoxepins, a process for their preparation and their use as medicaments
FR2462438A1 (fr) Nouveaux derives de la 6-alkyl-7-phenyl-1,6-naphtyridine-5(6h)-one, leur preparation et leur application comme medicaments
US4391818A (en) 4-(Substituted alkyl)-N-(1,3-dithiolan-2-ylidene(aniline
HU184791B (en) Process for preparing derivatives of tetrahydro-pyrid-4-yl-indole
US4156009A (en) Diazepine derivatives
US4180577A (en) Furo[2, 3d]pyrimidine derivatives and anti-ulcer containing the same
JPH0154326B2 (enExample)
DE2605824A1 (de) N-acylaniline, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
KR100246821B1 (ko) 비스테로이드성 소염진통제인 티아펜타렌카르복실산 유도체
US4486429A (en) Amino derivatives of 4-phenyl 4-oxobuten-2-oic acid, pharmaceutical compositions containing them, and methods for preparing and therapeutically using them
US3452141A (en) Methods of treating pain with n**alpha-phthaloyl-alpha-amino acid amides
KR840002308B1 (ko) 테트라 하이드로 피리드-4-일-인돌 유도체의 제조방법

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

R17-X000 Change to representative recorded

St.27 status event code: A-3-3-R10-R17-oth-X000

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

G160 Decision to publish patent application
PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

GRNT Written decision to grant
PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

FPAY Annual fee payment

Payment date: 19920917

Year of fee payment: 5

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 5

LAPS Lapse due to unpaid annual fee
PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 19931012

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 19931012

PN2301 Change of applicant

St.27 status event code: A-5-5-R10-R13-asn-PN2301

St.27 status event code: A-5-5-R10-R11-asn-PN2301