KR880001298A - 화학적으로 변형되지 않은 γ- 글로부린을 열처리하는 방법 - Google Patents

화학적으로 변형되지 않은 γ- 글로부린을 열처리하는 방법 Download PDF

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Publication number
KR880001298A
KR880001298A KR1019870007233A KR870007233A KR880001298A KR 880001298 A KR880001298 A KR 880001298A KR 1019870007233 A KR1019870007233 A KR 1019870007233A KR 870007233 A KR870007233 A KR 870007233A KR 880001298 A KR880001298 A KR 880001298A
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KR
South Korea
Prior art keywords
aqueous solution
globulin
heat treat
sorbitol
chemically unmodified
Prior art date
Application number
KR1019870007233A
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English (en)
Other versions
KR960015104B1 (ko
Inventor
유타까 히라오
카쓰히로 우리유
카즈오 다께찌
야히로 우에무라
Original Assignee
마쓰시다 렌죠
가부시끼가이샤 미도리쥬지
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 마쓰시다 렌죠, 가부시끼가이샤 미도리쥬지 filed Critical 마쓰시다 렌죠
Publication of KR880001298A publication Critical patent/KR880001298A/ko
Application granted granted Critical
Publication of KR960015104B1 publication Critical patent/KR960015104B1/ko
Priority to KR1019970034234A priority Critical patent/KR100263005B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

내용 없음

Description

화학적으로 변형되지 않는 γ-글로부린을 열처리하는 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (10)

  1. 화학적으로 변형되지 않은 γ-글로부린을 함유하는 수용액을 열처리하는 방법에 있어서, 솔비톨의 존재하에서 열처리함을 특징으로 하는 방법.
  2. 제1항에 있어서, 솔비톨이 수용액 100㎖당 10내지 70g의 양으로 존재하는 방법.
  3. 제2항에 있어서, 솔비톨이 수용액 100㎖당 30내지 70g의 양으로 존재하는 방법.
  4. 제3항에 있어서, 솔비톨이 수용액 100㎖당 40내지 60g의 양으로 존재하는 방법.
  5. 제1항에 있어서, 수용액의 이온강도가 0.01이하인 방법.
  6. 제5항에 있어서, 수용액의 이온강도가 0.001이하인 방법.
  7. 제1항에 있어서, 수용액의 pH가 4.5내지 6.5인 방법.
  8. 제7항에 있어서, 수용액의 pH가 5내지 6인 방법.
  9. 제1항에 있어서, 50내지 70℃의 온도에서 10분 내지 20시간동안 열처리하는 방법.
  10. 제1항에 있어서, 약 60℃의 온도에서 10시간 동안 열처리하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870007233A 1986-07-09 1987-07-07 화학적으로 변형되지 않은 γ-글로부린을 열처리하는 방법 KR960015104B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019970034234A KR100263005B1 (en) 1986-07-09 1997-07-18 Chemically unmodified ñ -globulin preparation

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP16158986 1986-07-09
JP161589/86 1986-07-09
JP161589 1986-07-09
JP61204760A JPH07103045B2 (ja) 1986-07-09 1986-08-30 非化学修飾γ−グロブリンの加熱処理方法
JP204760 1986-08-30
JP204760/86 1986-08-30

Publications (2)

Publication Number Publication Date
KR880001298A true KR880001298A (ko) 1988-04-22
KR960015104B1 KR960015104B1 (ko) 1996-10-28

Family

ID=15738004

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019870007233A KR960015104B1 (ko) 1986-07-09 1987-07-07 화학적으로 변형되지 않은 γ-글로부린을 열처리하는 방법

Country Status (2)

Country Link
JP (1) JPH07103045B2 (ko)
KR (1) KR960015104B1 (ko)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2547556B2 (ja) * 1987-02-06 1996-10-23 株式会社 ミドリ十字 ｒ−グロブリンの液状製剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5840532B2 (ja) * 1975-04-08 1983-09-06 カブシキガイシヤ ミドリジユウジ Ｉｇａ オヨビ ｉｇｍ ノネツアンテイカホウ
JPS553721A (en) * 1978-06-21 1980-01-11 Morinaga Milk Ind Co Ltd Production of powder of colostrum
DE3176491D1 (en) * 1980-03-05 1987-11-26 Miles Lab Pasteurized therapeutically active protein compositions
US4396608A (en) * 1981-08-24 1983-08-02 Cutter Laboratories Intravenously injectable immune serum globulin

Also Published As

Publication number Publication date
JPH07103045B2 (ja) 1995-11-08
JPS63146832A (ja) 1988-06-18
KR960015104B1 (ko) 1996-10-28

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