KR880000397A - 2-클로로-5-(트리클로로메틸) 피리딘의 3-위치를 선택적으로 염소화시키는 방법 - Google Patents

2-클로로-5-(트리클로로메틸) 피리딘의 3-위치를 선택적으로 염소화시키는 방법 Download PDF

Info

Publication number
KR880000397A
KR880000397A KR1019860004478A KR860004478A KR880000397A KR 880000397 A KR880000397 A KR 880000397A KR 1019860004478 A KR1019860004478 A KR 1019860004478A KR 860004478 A KR860004478 A KR 860004478A KR 880000397 A KR880000397 A KR 880000397A
Authority
KR
South Korea
Prior art keywords
pyridine
trichloromethyl
chloro
chlorinated
temperature
Prior art date
Application number
KR1019860004478A
Other languages
English (en)
Other versions
KR880002230B1 (ko
Inventor
험프레이스 파울라엘.
엘. 험프 레이스 파울라
제이.디트쉐 토마스
제이. 디트쉐 토마스
엘.빅스바이 제임스
엘. 빅스바이 제임스
Original Assignee
더 다우 케미칼 캄파니
리차드 고든 워터맨
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 더 다우 케미칼 캄파니, 리차드 고든 워터맨 filed Critical 더 다우 케미칼 캄파니
Priority to KR1019860004478A priority Critical patent/KR880002230B1/ko
Publication of KR880000397A publication Critical patent/KR880000397A/ko
Application granted granted Critical
Publication of KR880002230B1 publication Critical patent/KR880002230B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음

Description

2-클로로-5-(트리클로로메틸) 피리딘의 3-위치를 선택적으로 염소화시키는 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (11)

  1. 액상의 2-클로로-5-(트리클로로메틸) 피리딘을 텅스텐, 몰리브덴 또는 루테늄 촉매의 부재하에 압력 446 내지 6996KPa 및 온도 60℃ 내지 180℃에서 적정량의 CI2와 접촉시킴으로써, 2-3-디클로로-5-(트리클로로메틸) 피리딘이 2,6-디클로로-3-(트리클로로메틸) 피리딘에 대하여 적어도 2.8 : 1의 비로 제조됨을 특징으로 하여 2-클로로-5-(트리클로로메틸) 피리딘의 3-위치를 선택적으로 염소화시키는 방법.
  2. 제 1 항에 있어서, 2-클로로-5-(트리클로로메틸) 피리딘의 몰랑에 대하여 과잉몰량의 CI2를 사용하는 방법.
  3. 제 2 항에 있어서, 압력이 적어도 790KPa이고 온도가 100℃ 이상인 방법.
  4. 제 3 항에 있어서, 압력이 1480KPa이고 온도가 140℃ 내지 160℃인 방법.
  5. 제 4 항에 있어서, 온도가 약 150℃인 방법.
  6. 제 5 항에 있어서, 2,3-디클로로-5-(트리클로로메틸) 피리딘을 반응혼합물로부터 분리하는 단계를 추가로 포함하는 방법.
  7. 제 6 항에 있어서, 배치식 공정으로 수행하는 방법.
  8. 제 6 항에 있어서, 연속식 주기공정으로 수행하는 방법.
  9. 제 2 항에 있어서, 2-클로로-5-(트리클로로메틸) 피리딘이 염소화 β-피콜린 및 염소화 피리딘의 혼합물 중에 한 성분으로 공급되는 방법.
  10. 제 9 항에 있어서, 염소화 β-피콜린과 염소화 피리딘의 혼합물이 β-피콜린의 증기상 염소화로부터 수득되는 반응생성혼합물인 방법.
  11. 제 1 항에 있어서, HCI을 반응혼합물에 연속적으로 첨가하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860004478A 1986-06-05 1986-06-05 2-클로로-5-(트리클로로메틸)피리딘의 3-위치를 선택적으로 염소화시키는 방법 KR880002230B1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1019860004478A KR880002230B1 (ko) 1986-06-05 1986-06-05 2-클로로-5-(트리클로로메틸)피리딘의 3-위치를 선택적으로 염소화시키는 방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019860004478A KR880002230B1 (ko) 1986-06-05 1986-06-05 2-클로로-5-(트리클로로메틸)피리딘의 3-위치를 선택적으로 염소화시키는 방법

Publications (2)

Publication Number Publication Date
KR880000397A true KR880000397A (ko) 1988-03-25
KR880002230B1 KR880002230B1 (ko) 1988-10-20

Family

ID=19250337

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860004478A KR880002230B1 (ko) 1986-06-05 1986-06-05 2-클로로-5-(트리클로로메틸)피리딘의 3-위치를 선택적으로 염소화시키는 방법

Country Status (1)

Country Link
KR (1) KR880002230B1 (ko)

Also Published As

Publication number Publication date
KR880002230B1 (ko) 1988-10-20

Similar Documents

Publication Publication Date Title
KR880011057A (ko) 촉매의 존재하에 히드로플루오르화에 의한1,1.1-트리플루오로-2,2-디클로로에탄의 제조방법
GB1141369A (en) Process for the oxychlorination of organic compounds
KR840002356A (ko) 3-클로로-5-트리플루오로메틸피리딘의 제조방법
KR830009026A (ko) 2,3-디클로로-5-트리클로로메틸피리딘의 제조방법
KR970001290A (ko) 디플루오로메탄의 제조방법
KR960022411A (ko) 디플루오로메탄의 제조방법
Fahey The homogeneous palladium-catalysed ortho-chlorination of azobenzene
KR880000397A (ko) 2-클로로-5-(트리클로로메틸) 피리딘의 3-위치를 선택적으로 염소화시키는 방법
BR8201834A (pt) Processo de preparacao de piridina substituidas
GB1340421A (en) Manufacture of chlorofluoropyridines
KR930701370A (ko) 1,1-디클로로-1-플루오로에탄의 제조방법
KR930023342A (ko) 2-클로로-5-클로로메틸- 피리딘의 제조방법
KR930007876A (ko) 1,1,2-트리플루오로-1,2-디클로로에탄을 1,1,1-트리플루오로-2,2-디클로로에탄으로 이성체화 시키는 방법
KR950704255A (ko) 염소화 방법(Chlorination process)
KR890700569A (ko) 3-클로로-4-폴로로니트로벤젠의 제법
ES402319A1 (es) Procedimiento para la perfluoracion de compuestos perclora-dos funcionales.
KR900017971A (ko) 할로겐화된 시클로부테노아렌의 제조 방법
KR960000871A (ko) 2,5-디히드로푸란의 제조 방법
FR2553768B1 (fr) Procede pour la preparation de la 2-chloropyridine
US2485256A (en) Manufacture of quaternary nitrogen compounds
FR2375168B1 (ko)
GR3006678T3 (ko)
KR890701561A (ko) 2,3,5,6-테트라클로로피리딘 및 2,3,6-트리클로로피리딘의 제조방법
GB1334922A (en) Manufacture of halogenated pyridine derivatives
KR880012505A (ko) 신규 염소화 방법

Legal Events

Date Code Title Description
A201 Request for examination
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 20050907

Year of fee payment: 18

EXPY Expiration of term