KR870002839A - 저작성 캅셀제의 제조방법 - Google Patents

저작성 캅셀제의 제조방법 Download PDF

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Publication number
KR870002839A
KR870002839A KR1019860007591A KR860007591A KR870002839A KR 870002839 A KR870002839 A KR 870002839A KR 1019860007591 A KR1019860007591 A KR 1019860007591A KR 860007591 A KR860007591 A KR 860007591A KR 870002839 A KR870002839 A KR 870002839A
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KR
South Korea
Prior art keywords
carrier
composition
agent
solid
chewable
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KR1019860007591A
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English (en)
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KR940002656B1 (ko
Inventor
엘우드 존스 브라이언
매리온 나이트 폴라
알렉산더 워커 마크
Original Assignee
더 알 크라우더
릴리 인더스트리스 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 더 알 크라우더, 릴리 인더스트리스 리미티드 filed Critical 더 알 크라우더
Publication of KR870002839A publication Critical patent/KR870002839A/ko
Application granted granted Critical
Publication of KR940002656B1 publication Critical patent/KR940002656B1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

내용 없음

Description

저작성 캅셀제의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (14)

  1. a) 구강 흡수용 또는 구강 활성을 갖는 성분과 무독성 담체로 이루어진 반고체 조성물 및 b) 저작증진제(masticatory enhancing agent)로 이루어진 저작성 조성물(이 저작성 조성물은 100°C 이하에서는 액체상태이다)을 캅셀제 외피내에 넣음을 특징으로 하여, 상기 저작성 조성물을 함유하는 경질 젤라틴 캅셀제를 제조하는 방법.
  2. a) 구강 흡수용 또는 구강 활성을 갖는 성분, b)무독성 반고체 담체 및 c) 저작 증진제로 이루어진 저작성 조성물(이 저작성 조성물은 100°C 이하의 온도에서는 액체상태이다)을 캅셀제 외피내에 넣음을 특징으로 하여, 상기 저작성 조성물을 함유하는 경질 젤라틴 캅셀제를 제조하는 방법.
  3. 제 1 또는 2항에 있어서, 저작제가 안정화제 또는 현탄제인 방법.
  4. 제 3 항에 있어서, 저작제가 검인 방법.
  5. 제 4항에 있어서, 검이 크산탄 검인 방법.
  6. 제 1 내지 5항중 어느 항에 있어서, 담체가 분자량 200 내지 10,000을 갖는 폴리에틸렌 글리콜인 방법.
  7. 제 1 내지 5항중 어느 항에 있어서, 담체가 분자량 400 내지 4000을 갖는 폴리에틸렌 글리콜인 방법.
  8. 제 7항에 있어서, 폴리에틸렌 글리콜이 분자량 1000 내지 2000을 갖는 방법.
  9. 제 1 내지 8항중 어느 한 항에 있어서, 조성물이 활성 성분을 95중량%까지 함유하는 방법.
  10. 제 9항에 있어서, 조성물이 고체 활성 성분을 20%까지 함유하는 방법.
  11. 제 1 내지 10항중 어느 한 항에 있어서, 활성성분이 심장 작용성 약제 또는 진통제인 방법.
  12. 제 1항에 있어서, 구강 흡수용 또는 구강 활성을 갖는 성분이 액체이고 담체가 고체인 방법.
  13. 제 12항에 있어서, 담체가 콜로이드성 이산화실리콘 또는 셀룰로오즈 유도체인 방법.
  14. 제 1내지 13항중 어느 한 항에 있어서, 조성물이 추가로 풍미제를 함유하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860007591A 1985-09-11 1986-09-10 저작성 캅셀제의 제조방법 KR940002656B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8522453 1985-09-11
GB858522453A GB8522453D0 (en) 1985-09-11 1985-09-11 Chewable capsules

Publications (2)

Publication Number Publication Date
KR870002839A true KR870002839A (ko) 1987-04-13
KR940002656B1 KR940002656B1 (ko) 1994-03-28

Family

ID=10584991

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860007591A KR940002656B1 (ko) 1985-09-11 1986-09-10 저작성 캅셀제의 제조방법

Country Status (22)

Country Link
US (1) US4755389A (ko)
EP (1) EP0215635B1 (ko)
JP (1) JPH089535B2 (ko)
KR (1) KR940002656B1 (ko)
CN (1) CN1026463C (ko)
AT (1) ATE69377T1 (ko)
AU (1) AU590792B2 (ko)
CA (1) CA1273295A (ko)
DE (1) DE3682467D1 (ko)
DK (1) DK174973B1 (ko)
EG (1) EG17919A (ko)
ES (1) ES2002302A6 (ko)
GB (1) GB8522453D0 (ko)
GR (1) GR862293B (ko)
HU (1) HU198837B (ko)
IE (1) IE59738B1 (ko)
IL (1) IL79973A (ko)
NZ (1) NZ217494A (ko)
PH (1) PH22155A (ko)
PT (1) PT83327B (ko)
RU (1) RU2018305C1 (ko)
ZA (1) ZA866849B (ko)

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RU2018305C1 (ru) 1994-08-30
IL79973A0 (en) 1986-12-31
IL79973A (en) 1990-06-10
DE3682467D1 (de) 1992-02-27
EP0215635A3 (en) 1988-01-13
US4755389A (en) 1988-07-05
CN1026463C (zh) 1994-11-09
IE59738B1 (en) 1994-03-23
HU198837B (en) 1989-12-28
PT83327B (pt) 1989-05-12
JPH089535B2 (ja) 1996-01-31
DK433886A (da) 1987-03-12
DK433886D0 (da) 1986-09-10
PH22155A (en) 1988-06-01
ZA866849B (en) 1987-11-25
KR940002656B1 (ko) 1994-03-28
AU6245586A (en) 1987-03-12
ATE69377T1 (de) 1991-11-15
DK174973B1 (da) 2004-04-05
PT83327A (en) 1986-10-01
EP0215635A2 (en) 1987-03-25
GR862293B (en) 1987-01-02
CN86106150A (zh) 1987-03-18
IE862403L (en) 1987-03-11
GB8522453D0 (en) 1985-10-16
AU590792B2 (en) 1989-11-16
JPS62116508A (ja) 1987-05-28
EG17919A (en) 1991-06-30
NZ217494A (en) 1989-03-29
EP0215635B1 (en) 1992-01-15
CA1273295A (en) 1990-08-28
ES2002302A6 (es) 1988-08-01
HUT43951A (en) 1988-01-28

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