KR860008279A - 트립토판의 정제방법 - Google Patents

트립토판의 정제방법 Download PDF

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Publication number
KR860008279A
KR860008279A KR1019860002726A KR860002726A KR860008279A KR 860008279 A KR860008279 A KR 860008279A KR 1019860002726 A KR1019860002726 A KR 1019860002726A KR 860002726 A KR860002726 A KR 860002726A KR 860008279 A KR860008279 A KR 860008279A
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KR
South Korea
Prior art keywords
tryptophan
indole
aqueous solution
purifying
resin
Prior art date
Application number
KR1019860002726A
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English (en)
Other versions
KR890001245B1 (ko
Inventor
쇼오이찌로 미야하라
도시오 마쯔모또
도오루 미야하라
가즈나리 닛다
Original Assignee
미쯔이도오아쯔가가꾸 가부시기가이샤
도쯔까 야스아끼
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP60074486A external-priority patent/JPS61234789A/ja
Priority claimed from JP61058404A external-priority patent/JPH0761996B2/ja
Application filed by 미쯔이도오아쯔가가꾸 가부시기가이샤, 도쯔까 야스아끼 filed Critical 미쯔이도오아쯔가가꾸 가부시기가이샤
Publication of KR860008279A publication Critical patent/KR860008279A/ko
Application granted granted Critical
Publication of KR890001245B1 publication Critical patent/KR890001245B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan

Abstract

내용 없음

Description

트립토판의 정제방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 원료물질인 인돌로부터 효소작용에 의해 제조된 트립토판의 반응액을 다공성 양이온 교환수지층을 통과시켜서, 수지의 이온교환부에 트립토판을 흡착시키는 한편 수지의 다공부에 인돌을 흡착시킨후, 수지의 이온교환부에 흡착된 트립토판만을 알카리 수용액 혹은 산수용액으로 용리시켜 인돌을 거의 포함하지 않는 트립토판을 얻는 것을 특징으로 하는 트립토판의 정제방법.
  2. 제1항에 있어서, 상기의 트립토판용리제로 사용한 알카리 수용액은 암모니아 수용액인 것을 특징으로 하는 트립토판의 정제방법.
  3. 월료물질인 인돌로부터 효소작용에 의해 제조된 트립토판의 반응액을 다공성 양이온 교환수지층을 통과시키고, 수지의 이온 교환부에 트립토판을 흡착 및 용리시키는 처리와 재생을 반복해서 행하고, 이어서 수지의 다공부에 흡착된 인돌을 물과 혼화될 수 있는 함수 유기용매로 용리시키고, 얻어진 용리액으로부터 인돌을 유리시키는 것을 특징으로 하는 트립토판 반응액으로부터 인돌을 분리 및 회수하는 방법.
  4. 제3항에 있어서, 상기의 물과 혼화될 수 있는 함수 유기용매는 저급의 지방족 알코을 수용액인 것을 특징으로 하는 트립토판의 정제방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019860002726A 1985-04-10 1986-04-10 트립토판의 정제방법 KR890001245B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP60-74486 1985-04-10
JP74486 1985-04-10
JP60074486A JPS61234789A (ja) 1985-04-10 1985-04-10 Ｌ―トリプトファンよりインドールの分離回収方法
JP61-58404 1986-03-18
JP61058404A JPH0761996B2 (ja) 1986-03-18 1986-03-18 トリプトフアンの精製方法

Publications (2)

Publication Number Publication Date
KR860008279A true KR860008279A (ko) 1986-11-14
KR890001245B1 KR890001245B1 (ko) 1989-04-28

Family

ID=26399459

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860002726A KR890001245B1 (ko) 1985-04-10 1986-04-10 트립토판의 정제방법

Country Status (6)

Country Link
US (1) US4769474A (ko)
EP (1) EP0200944B1 (ko)
KR (1) KR890001245B1 (ko)
AU (1) AU570839B2 (ko)
CA (1) CA1267652A (ko)
DE (1) DE3685846T2 (ko)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100339163B1 (ko) * 1995-02-10 2002-12-05 주식회사 엘지씨아이 생강으로부터나트륨치환트립토판을추출하는방법
KR20120107996A (ko) * 2009-12-22 2012-10-04 솔베이 스페셜티 폴리머즈 유에스에이, 엘.엘.씨. 디벤조디아조신 단위를 포함하는 신규 폴리아미드, 폴리이미드 또는 폴리아미드-이미드
CN114082222A (zh) * 2021-10-25 2022-02-25 青海大学 狭果茶藨子游离氨基酸纯化方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0648990B2 (ja) * 1987-01-14 1994-06-29 味の素株式会社 トリプトフアンの精製方法
JPH01311062A (ja) * 1988-06-08 1989-12-15 Agency Of Ind Science & Technol インドールの分離精製法
DE69010155T2 (de) * 1989-11-20 1994-12-08 Mitsui Toatsu Chemicals Verfahren zur Trennung von Aminosäuren.
US7030248B2 (en) 1998-02-26 2006-04-18 Aminopath Labs, Llc Isolation of natural L-β-3-indolylalanine and enrichment of natural aliphatic amino acid mixtures with natural L-β-3-indolylalanine
US6541644B2 (en) 1998-02-26 2003-04-01 Aminopath Labs, Llc Isolation of natural L-β-3-indolylalanine and enrichment of natural aliphatic amino acid mixtures with natural L-β-3-indolylalanine
US20060106226A1 (en) * 1998-02-26 2006-05-18 Aminopath Labs, Llc And A Patent License Agreement Isolation of amino acids and related isolates
US7329354B2 (en) * 1998-06-09 2008-02-12 Ppt Technologies, Llc Purification of organic solvent fluids
CA2417639A1 (en) * 1999-08-30 2001-03-08 Robert L. Pollack Isolation of natural l-.beta.-3-indolylalanine and enrichment of natural aliphatic amino acid mixtures with natural l-.beta.-3-indolylalanine
JP2001199957A (ja) * 2000-01-13 2001-07-24 Ajinomoto Co Inc トリプトファンの晶析法
AU2004268627A1 (en) * 2003-08-27 2005-03-10 3M Innovative Properties Company Water filter manifold with integral valve
ITFI20040063A1 (it) * 2004-03-19 2004-06-19 Biosphere S P A Processo per la purificazione di triptofano
US20070161784A1 (en) * 2006-01-11 2007-07-12 Aminopath Labs, Llc Methods and products of amino acid isolation
EP3092218B1 (fr) * 2014-01-07 2022-03-09 Novasep Process Solutions Procédé de purification d'acides aminés aromatiques
US20180001314A1 (en) * 2015-01-22 2018-01-04 Evoqua Water Technologies Llc Chromatography media and ion exchange resin performance restoration
CN111253298A (zh) * 2020-02-10 2020-06-09 南阳师范学院 超高交联吸附树脂对l-色氨酸的分离方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH445129A (fr) * 1964-04-29 1967-10-15 Nestle Sa Procédé pour la préparation de composés d'inclusion à poids moléculaire élevé
GB1145512A (en) * 1965-09-21 1969-03-19 Kyowa Hakko Kogyo Company Ltd Method for isolating tryptophan
DE2943761C2 (de) * 1979-10-30 1983-11-17 Degussa Ag, 6000 Frankfurt Verfahren zur Isolierung von Aminosäuren, die mindestens einen aromatischen oder heteroaromatischen Ring enthalten
US4357276A (en) * 1979-11-02 1982-11-02 Asahi Kasei Kogyo Kabushiki Kaisha Process for separation of indole using X and Y type zeolites
JPS5928484A (ja) * 1982-08-11 1984-02-15 Mitsui Toatsu Chem Inc Ｌ−アミノ酸の単離方法
JPH01189265A (ja) * 1988-01-25 1989-07-28 Pioneer Answerphone Mfg Corp 留守番電話装置

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100339163B1 (ko) * 1995-02-10 2002-12-05 주식회사 엘지씨아이 생강으로부터나트륨치환트립토판을추출하는방법
KR20120107996A (ko) * 2009-12-22 2012-10-04 솔베이 스페셜티 폴리머즈 유에스에이, 엘.엘.씨. 디벤조디아조신 단위를 포함하는 신규 폴리아미드, 폴리이미드 또는 폴리아미드-이미드
CN114082222A (zh) * 2021-10-25 2022-02-25 青海大学 狭果茶藨子游离氨基酸纯化方法

Also Published As

Publication number Publication date
KR890001245B1 (ko) 1989-04-28
AU5572686A (en) 1986-10-16
CA1267652A (en) 1990-04-10
US4769474A (en) 1988-09-06
EP0200944A2 (en) 1986-11-12
EP0200944A3 (en) 1988-08-17
AU570839B2 (en) 1988-03-24
DE3685846D1 (de) 1992-08-06
EP0200944B1 (en) 1992-07-01
DE3685846T2 (de) 1993-01-14

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