KR850003535A - 4-아미노-6,7-디메톡시2-[4--피페라진-1-일]-퀴나졸린 및 생리적으로 적합한 그염의 제조방법 - Google Patents

4-아미노-6,7-디메톡시2-[4--피페라진-1-일]-퀴나졸린 및 생리적으로 적합한 그염의 제조방법

Info

Publication number
KR850003535A
KR850003535A KR1019840001035A KR840001035A KR850003535A KR 850003535 A KR850003535 A KR 850003535A KR 1019840001035 A KR1019840001035 A KR 1019840001035A KR 840001035 A KR840001035 A KR 840001035A KR 850003535 A KR850003535 A KR 850003535A
Authority
KR
South Korea
Prior art keywords
piperazin
amino
dimethoxy2
quinazolin
preparing
Prior art date
Application number
KR1019840001035A
Other languages
English (en)
Other versions
KR900001420B1 (ko
Inventor
쉬크카네데르 헬뮤트
헤닝 아흐렌스 쿠우르트
Original Assignee
루드빅 허이만 운트 콤파니 게엠베하
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 루드빅 허이만 운트 콤파니 게엠베하 filed Critical 루드빅 허이만 운트 콤파니 게엠베하
Publication of KR850003535A publication Critical patent/KR850003535A/ko
Application granted granted Critical
Publication of KR900001420B1 publication Critical patent/KR900001420B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
KR1019840001035A 1983-11-22 1984-02-29 4-아미노-6,7-디메톡시2-[4-(푸로-2-일)-피페라진-1-일]-퀴나졸린 및 생리적으로 적합한 그염의 제조방법 KR900001420B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP83111671A EP0146642B1 (de) 1983-11-22 1983-11-22 Verfahren zur Herstellung von 4-Amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-chinazolin und dessen physiologisch annehmbarer Salze
EP83111671.0 1983-11-22

Publications (2)

Publication Number Publication Date
KR850003535A true KR850003535A (ko) 1985-06-20
KR900001420B1 KR900001420B1 (ko) 1990-03-09

Family

ID=8190822

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019840001035A KR900001420B1 (ko) 1983-11-22 1984-02-29 4-아미노-6,7-디메톡시2-[4-(푸로-2-일)-피페라진-1-일]-퀴나졸린 및 생리적으로 적합한 그염의 제조방법

Country Status (18)

Country Link
US (1) US4647684A (ko)
EP (1) EP0146642B1 (ko)
JP (1) JPS60112787A (ko)
KR (1) KR900001420B1 (ko)
AT (1) ATE32074T1 (ko)
AU (1) AU560948B2 (ko)
CA (1) CA1243677A (ko)
DE (1) DE3375395D1 (ko)
DK (1) DK162643C (ko)
ES (1) ES8506291A1 (ko)
GR (1) GR82237B (ko)
HU (1) HU191252B (ko)
IE (1) IE57099B1 (ko)
IL (1) IL71085A (ko)
NZ (1) NZ207487A (ko)
PT (1) PT78161B (ko)
YU (1) YU44986B (ko)
ZA (1) ZA841360B (ko)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3375395D1 (en) * 1983-11-22 1988-02-25 Heumann Ludwig & Co Gmbh Process for the preparation of 4-amino-6,7-dimethoxy-2-(4-(furoyl-2)-piperazin-1-yl)-quinazoline and its physiologically acceptable salt
ATE72244T1 (de) * 1986-03-21 1992-02-15 Heumann Pharma Gmbh & Co Kristalline, wasserfreie sigma -form von 2-(4-(2furoyl-(2-piperazin)-1-yl>-4-amino-6,7- dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung.
FR2618159B2 (fr) * 1987-07-15 1990-02-02 Transgene Sa Procede de stabilisation d'un plasmide contenu dans une souche bacterienne et souche obtenue
YU70890A (en) * 1989-04-21 1992-05-28 Egyt Gyogyszervegyeszeti Gyar Process for obtaining quinazoline derivatives
GB9708917D0 (en) * 1997-05-01 1997-06-25 Pfizer Ltd Compounds useful in therapy
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4001237A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company Oxazole, isoxazole, thiazole and isothiazole amides
US4138651A (en) * 1977-09-06 1979-02-06 Rockwell International Corporation Multiple magnetic layer composite for magnetostatic surface wave propagation
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
FI59800C (fi) * 1979-01-10 1981-10-12 Fermion Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin
US4285878A (en) * 1980-01-31 1981-08-25 Smithkline Corporation N-Phenyl-N'-cyano-O-phenylisoureas
DE3014353A1 (de) * 1980-04-15 1982-01-21 Bayer Ag, 5090 Leverkusen Trisubstituierte cyanguanidine, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
DE3336409A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Chinazolinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3375395D1 (en) * 1983-11-22 1988-02-25 Heumann Ludwig & Co Gmbh Process for the preparation of 4-amino-6,7-dimethoxy-2-(4-(furoyl-2)-piperazin-1-yl)-quinazoline and its physiologically acceptable salt

Also Published As

Publication number Publication date
NZ207487A (en) 1986-05-09
DE3375395D1 (en) 1988-02-25
IL71085A (en) 1987-10-30
ES530199A0 (es) 1985-07-16
CA1243677A (en) 1988-10-25
ES8506291A1 (es) 1985-07-16
YU44986B (en) 1991-06-30
PT78161A (de) 1984-03-01
PT78161B (de) 1986-04-28
AU560948B2 (en) 1987-04-30
AU2502484A (en) 1985-05-30
IL71085A0 (en) 1984-05-31
IE57099B1 (en) 1992-04-22
YU37484A (en) 1986-12-31
DK162643C (da) 1992-04-13
HU191252B (en) 1987-01-28
EP0146642B1 (de) 1988-01-20
EP0146642A1 (de) 1985-07-03
KR900001420B1 (ko) 1990-03-09
US4647684A (en) 1987-03-03
ZA841360B (en) 1984-10-31
GR82237B (ko) 1984-12-13
DK106284D0 (da) 1984-02-27
DK162643B (da) 1991-11-25
HUT37144A (en) 1985-11-28
JPS60112787A (ja) 1985-06-19
IE840646L (en) 1985-05-22
JPH0425956B2 (ko) 1992-05-06
DK106284A (da) 1985-05-23
ATE32074T1 (de) 1988-02-15

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