DK106284D0 - Fremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-quinazoling og dens fysiologisk acceptable salte - Google Patents
Fremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-quinazoling og dens fysiologisk acceptable salteInfo
- Publication number
- DK106284D0 DK106284D0 DK1062/84A DK106284A DK106284D0 DK 106284 D0 DK106284 D0 DK 106284D0 DK 1062/84 A DK1062/84 A DK 1062/84A DK 106284 A DK106284 A DK 106284A DK 106284 D0 DK106284 D0 DK 106284D0
- Authority
- DK
- Denmark
- Prior art keywords
- furo
- piperazin
- dimethoxy
- amino
- quinazoling
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP83111671 | 1983-11-22 | ||
EP83111671A EP0146642B1 (de) | 1983-11-22 | 1983-11-22 | Verfahren zur Herstellung von 4-Amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-chinazolin und dessen physiologisch annehmbarer Salze |
Publications (4)
Publication Number | Publication Date |
---|---|
DK106284D0 true DK106284D0 (da) | 1984-02-27 |
DK106284A DK106284A (da) | 1985-05-23 |
DK162643B DK162643B (da) | 1991-11-25 |
DK162643C DK162643C (da) | 1992-04-13 |
Family
ID=8190822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK106284A DK162643C (da) | 1983-11-22 | 1984-02-27 | Fremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-quinazolin og fysiologisk acceptable syreadditinssalte heraf, og udgangsmateriale til anvendelse ved fremgangsmaaden |
Country Status (18)
Country | Link |
---|---|
US (1) | US4647684A (da) |
EP (1) | EP0146642B1 (da) |
JP (1) | JPS60112787A (da) |
KR (1) | KR900001420B1 (da) |
AT (1) | ATE32074T1 (da) |
AU (1) | AU560948B2 (da) |
CA (1) | CA1243677A (da) |
DE (1) | DE3375395D1 (da) |
DK (1) | DK162643C (da) |
ES (1) | ES530199A0 (da) |
GR (1) | GR82237B (da) |
HU (1) | HU191252B (da) |
IE (1) | IE57099B1 (da) |
IL (1) | IL71085A (da) |
NZ (1) | NZ207487A (da) |
PT (1) | PT78161B (da) |
YU (1) | YU44986B (da) |
ZA (1) | ZA841360B (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0146642B1 (de) * | 1983-11-22 | 1988-01-20 | LUDWIG HEUMANN & CO GMBH | Verfahren zur Herstellung von 4-Amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-chinazolin und dessen physiologisch annehmbarer Salze |
ATE72244T1 (de) * | 1986-03-21 | 1992-02-15 | Heumann Pharma Gmbh & Co | Kristalline, wasserfreie sigma -form von 2-(4-(2furoyl-(2-piperazin)-1-yl>-4-amino-6,7- dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung. |
FR2618159B2 (fr) * | 1987-07-15 | 1990-02-02 | Transgene Sa | Procede de stabilisation d'un plasmide contenu dans une souche bacterienne et souche obtenue |
YU70890A (en) * | 1989-04-21 | 1992-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for obtaining quinazoline derivatives |
GB9708917D0 (en) * | 1997-05-01 | 1997-06-25 | Pfizer Ltd | Compounds useful in therapy |
KR101427221B1 (ko) * | 2012-08-29 | 2014-08-13 | 주식회사 에스텍파마 | 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4001237A (en) * | 1976-02-18 | 1977-01-04 | Bristol-Myers Company | Oxazole, isoxazole, thiazole and isothiazole amides |
US4138651A (en) * | 1977-09-06 | 1979-02-06 | Rockwell International Corporation | Multiple magnetic layer composite for magnetostatic surface wave propagation |
US4138561A (en) * | 1977-09-30 | 1979-02-06 | Bristol-Myers Company | Cyanocarboxamidines and quinazoline process |
FI59800C (fi) * | 1979-01-10 | 1981-10-12 | Fermion Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin |
US4285878A (en) * | 1980-01-31 | 1981-08-25 | Smithkline Corporation | N-Phenyl-N'-cyano-O-phenylisoureas |
DE3014353A1 (de) * | 1980-04-15 | 1982-01-21 | Bayer Ag, 5090 Leverkusen | Trisubstituierte cyanguanidine, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide |
DE3336409A1 (de) * | 1983-10-06 | 1985-04-18 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Chinazolinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
EP0146642B1 (de) * | 1983-11-22 | 1988-01-20 | LUDWIG HEUMANN & CO GMBH | Verfahren zur Herstellung von 4-Amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-chinazolin und dessen physiologisch annehmbarer Salze |
-
1983
- 1983-11-22 EP EP83111671A patent/EP0146642B1/de not_active Expired
- 1983-11-22 DE DE8383111671T patent/DE3375395D1/de not_active Expired
- 1983-11-22 AT AT83111671T patent/ATE32074T1/de active
-
1984
- 1984-02-23 CA CA000448121A patent/CA1243677A/en not_active Expired
- 1984-02-24 ZA ZA841360A patent/ZA841360B/xx unknown
- 1984-02-24 AU AU25024/84A patent/AU560948B2/en not_active Ceased
- 1984-02-24 GR GR73914A patent/GR82237B/el unknown
- 1984-02-27 DK DK106284A patent/DK162643C/da not_active IP Right Cessation
- 1984-02-27 IL IL71085A patent/IL71085A/xx unknown
- 1984-02-28 PT PT78161A patent/PT78161B/pt not_active IP Right Cessation
- 1984-02-29 YU YU374/84A patent/YU44986B/xx unknown
- 1984-02-29 HU HU84821A patent/HU191252B/hu not_active IP Right Cessation
- 1984-02-29 KR KR1019840001035A patent/KR900001420B1/ko not_active IP Right Cessation
- 1984-03-01 ES ES530199A patent/ES530199A0/es active Granted
- 1984-03-13 NZ NZ207487A patent/NZ207487A/en unknown
- 1984-03-15 IE IE646/84A patent/IE57099B1/en not_active IP Right Cessation
- 1984-03-16 JP JP59052070A patent/JPS60112787A/ja active Granted
- 1984-03-16 US US06/590,231 patent/US4647684A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
NZ207487A (en) | 1986-05-09 |
EP0146642B1 (de) | 1988-01-20 |
GR82237B (da) | 1984-12-13 |
IL71085A0 (en) | 1984-05-31 |
AU560948B2 (en) | 1987-04-30 |
DE3375395D1 (en) | 1988-02-25 |
DK162643B (da) | 1991-11-25 |
ATE32074T1 (de) | 1988-02-15 |
JPS60112787A (ja) | 1985-06-19 |
HUT37144A (en) | 1985-11-28 |
IE57099B1 (en) | 1992-04-22 |
DK106284A (da) | 1985-05-23 |
PT78161A (de) | 1984-03-01 |
YU44986B (en) | 1991-06-30 |
ES8506291A1 (es) | 1985-07-16 |
ZA841360B (en) | 1984-10-31 |
IE840646L (en) | 1985-05-22 |
AU2502484A (en) | 1985-05-30 |
DK162643C (da) | 1992-04-13 |
KR850003535A (ko) | 1985-06-20 |
ES530199A0 (es) | 1985-07-16 |
JPH0425956B2 (da) | 1992-05-06 |
HU191252B (en) | 1987-01-28 |
US4647684A (en) | 1987-03-03 |
KR900001420B1 (ko) | 1990-03-09 |
IL71085A (en) | 1987-10-30 |
PT78161B (de) | 1986-04-28 |
EP0146642A1 (de) | 1985-07-03 |
CA1243677A (en) | 1988-10-25 |
YU37484A (en) | 1986-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
TNSN04199A1 (en) | Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use | |
RO116898B1 (ro) | Derivaţi de dioxizi de benzotiazină, procedeu pentru prepararea acestora, intermediari, compoziţie farmaceutică şi metodă pentru inhibarea nivelurilor crescute de endotelină | |
DK106284D0 (da) | Fremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)-quinazoling og dens fysiologisk acceptable salte | |
PL336640A1 (en) | Substituted 3,3-diamino-2- propenonitriles, their production and application | |
RU94003397A (ru) | Производные 2-/4-(4-азолилбутил)-1-пиперазинил/-пиримидина, способ их получения и фармацевтическая композиция на их основе | |
IT8821725A0 (it) | Elemento costruttivo, nonche' metodo per la produzione dello stesso. | |
ZA80501B (en) | Method for producing 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)quinazoline hydrochloride having an antihypertensive effect | |
ATE28200T1 (de) | Spiro(benzofuran-azalkane), eine methode zu deren herstellung und ihre verwendung als medikamente. | |
ZA777223B (en) | Method for the production of 6,7-dimethoxy-4-amino-2-(4-(2-furoyl)-1-piperazinyl)quinazoline having an antihypertensive effect | |
DK0521766T3 (da) | Hidtil ukendt fremgangsmåde til syntese af enantiomerer af 3-aminochromanderivater | |
IT9047532A1 (it) | Procedimento per la produzione di feltri per cappello. | |
YU36180A (en) | Process for producing the crystalline form of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-piperazine hydrochloride | |
DE3784851T2 (de) | Verfahren zur herstellung von 4-amino-1,2,4-(4h)-triazol-derivaten. | |
ZA777222B (en) | An intermediate product for the production of 6,7-dimethoxy-4-amino-2-(4-(furoyl)-1-piperazinyl)quinazoline having an antihypertensive effect | |
DE69912306D1 (de) | 1,4-diaryl-2-fluor-1-buten-3-ol-verbindungen und ihre verwendung in der herstellung von 1,4-diaryl-2-fluor-1,3-butadien- und 1,4-diaryl-2-fluor-2-buten-verbindungen | |
CS698288A1 (en) | Method of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl) piperazine's hydrochloride's crystalline alpha-form production | |
YU43835B (en) | Process for obtaining crystalline 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl)-piperazine hydrochloride | |
ATE98234T1 (de) | Verwendung von 4-(1-oxoalkyl>-2,5oxazolidindionen zur selektiven stereospezifischen bildung von biologisch wirkenden beta-lactamen. | |
DK435085D0 (da) | Fremgangsmaade til fremstilling af 5,6-dialkoxy-4-alkyl-2(1h)-quinazolinoner |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |