KR850000755B1 - Process for preparing 3,1-benzoxazin-2-ones and acid addition salts thereof - Google Patents

Process for preparing 3,1-benzoxazin-2-ones and acid addition salts thereof

Info

Publication number
KR850000755B1
KR850000755B1 KR8102523A KR810002523A KR850000755B1 KR 850000755 B1 KR850000755 B1 KR 850000755B1 KR 8102523 A KR8102523 A KR 8102523A KR 810002523 A KR810002523 A KR 810002523A KR 850000755 B1 KR850000755 B1 KR 850000755B1
Authority
KR
South Korea
Prior art keywords
formula
benzoxazin
ones
alkyl
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
KR8102523A
Other languages
English (en)
Korean (ko)
Other versions
KR830006248A (ko
Inventor
Anton Mentrup
Ernst-Otto Renth
Wolfram Gaida
Kurt Schromm
Wolfgang Hoefke
Ilse Streller
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of KR830006248A publication Critical patent/KR830006248A/ko
Priority to KR1019850001965A priority Critical patent/KR850000741B1/ko
Priority to KR1019850001963A priority patent/KR850000754B1/ko
Application granted granted Critical
Publication of KR850000755B1 publication Critical patent/KR850000755B1/ko
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
KR8102523A 1980-07-12 1981-07-11 Process for preparing 3,1-benzoxazin-2-ones and acid addition salts thereof Expired KR850000755B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1019850001965A KR850000741B1 (ko) 1980-07-12 1985-03-25 3,1-벤즈옥사진-2-온 및 이의 산 부가염의 제조방법
KR1019850001963A KR850000754B1 (ko) 1980-07-12 1985-03-25 3, 1-벤즈옥사진-2-온 및 이의 산부가염의 제조방법

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803026534 DE3026534A1 (de) 1980-07-12 1980-07-12 3,1-benzoxazin-2-one, ihre herstellung und verwendung

Related Child Applications (2)

Application Number Title Priority Date Filing Date
KR1019850001965A Division KR850000741B1 (ko) 1980-07-12 1985-03-25 3,1-벤즈옥사진-2-온 및 이의 산 부가염의 제조방법
KR1019850001963A Division KR850000754B1 (ko) 1980-07-12 1985-03-25 3, 1-벤즈옥사진-2-온 및 이의 산부가염의 제조방법

Publications (2)

Publication Number Publication Date
KR830006248A KR830006248A (ko) 1983-09-20
KR850000755B1 true KR850000755B1 (en) 1985-05-25

Family

ID=6107085

Family Applications (1)

Application Number Title Priority Date Filing Date
KR8102523A Expired KR850000755B1 (en) 1980-07-12 1981-07-11 Process for preparing 3,1-benzoxazin-2-ones and acid addition salts thereof

Country Status (25)

Country Link
US (1) US4341778A (https=)
EP (1) EP0043940B1 (https=)
JP (1) JPS5748975A (https=)
KR (1) KR850000755B1 (https=)
AT (1) ATE9336T1 (https=)
AU (1) AU540916B2 (https=)
CA (1) CA1165317A (https=)
DD (1) DD202018A5 (https=)
DE (2) DE3026534A1 (https=)
DK (1) DK149851C (https=)
ES (4) ES8205402A1 (https=)
FI (1) FI74703C (https=)
GB (1) GB2080296B (https=)
GR (1) GR74333B (https=)
HK (1) HK98286A (https=)
HU (1) HU183515B (https=)
IE (1) IE52508B1 (https=)
IL (1) IL63285A (https=)
NO (1) NO158578C (https=)
NZ (1) NZ197678A (https=)
PH (1) PH17425A (https=)
PT (1) PT73338B (https=)
SG (1) SG77686G (https=)
YU (1) YU170181A (https=)
ZA (1) ZA814687B (https=)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446319A (en) * 1981-04-28 1984-05-01 Takeda Chemical Industries, Ltd. Aminocyclitols and their production
JPS62238288A (ja) * 1986-04-04 1987-10-19 Nippon Tokushu Noyaku Seizo Kk 環状カルバメ−ト及び農園芸用殺菌剤
FR2636065B1 (fr) * 1988-09-08 1993-05-07 Fabre Sa Pierre Nouveaux derives de dihydro-2,3 arylacoylaminoalcoyl-3 4h-benzoxazine-1,3 ones-4, leur preparation et leur application en tant que medicaments utiles en therapeutique
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
FR2680172B1 (fr) * 1991-08-05 1993-11-19 Fabre Medicament Pierre Nouvelles piperazinylalcoyl-3 dihydro-2,3 4h-benzoxazine-1,3 ones-4 substituees, leur preparation et leur application en therapeutique.
CA2210138A1 (en) * 1995-01-24 1996-08-01 Peter D. Williams Tocolytic oxytocin receptor antagonists
US5874430A (en) * 1996-10-02 1999-02-23 Dupont Pharmaceuticals Company 4,4-disubstitued-1,4-dihydro-2H-3,1-benzoxazin-2-ones useful as HIV reverse transcriptase inhibitors and intermediates and processes for making the same
DE102004003428A1 (de) * 2004-01-23 2005-08-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Beta-2-Agonisten, und deren Verwendung als Arzneimittel
EP1844768A1 (en) * 2005-01-19 2007-10-17 Dainippon Sumitomo Pharma Co., Ltd. Aromatic sulfone compound as aldosterone receptor modulator
DE102005008921A1 (de) * 2005-02-24 2006-08-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von Atemwegserkrankungen
US7423146B2 (en) 2005-11-09 2008-09-09 Boehringer Ingelheim International Gmbh Process for the manufacturing of pharmaceutically active 3,1-benzoxazine-2-ones
PE20080425A1 (es) * 2006-08-22 2008-06-16 Boehringer Ingelheim Int Formulacion aerosol para la inhalacion de beta-agonistas
UY30550A1 (es) * 2006-08-22 2008-03-31 Boehringer Ingelheim Int Nuevos beta-agonistas enantioméricamente puros, procedimientos para su preparacion y su uso como medicamentos
EP2056836A1 (en) * 2006-08-22 2009-05-13 Boehringer Ingelheim International GmbH Powder formulations for inhalation containing enantiomerically pure beta-agonists
PE20081358A1 (es) * 2006-08-22 2008-10-31 Boehringer Ingelheim Int Combinaciones farmacologicas para el tratamiento de enfermedades de la vias aereas
EP2093219A1 (de) 2008-02-22 2009-08-26 Boehringer Ingelheim International Gmbh Kristalline, enantiomerenreine Salzform eines Betamimetikums und dessen Verwendung als Arzneimittel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3526621A (en) * 1966-08-03 1970-09-01 Farmaceutical Italia Soc Substituted 3,1-benzoxazin-2-one
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen
US4163053A (en) * 1977-12-27 1979-07-31 Schering Corporation Anti-hypertensive 5-[2-(substituted anilinoalkylamino)-1-hydroxyalkyl]salicylamides
DD144050A5 (de) * 1978-06-05 1980-09-24 Ciba Geigy Ag Verfahren zur herstellung von n-alkylierten aminoalkoholen
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen

Also Published As

Publication number Publication date
JPS5748975A (en) 1982-03-20
PT73338A (de) 1981-08-01
KR830006248A (ko) 1983-09-20
FI812183L (fi) 1982-01-13
YU170181A (en) 1983-10-31
GB2080296A (en) 1982-02-03
HU183515B (en) 1984-05-28
AU540916B2 (en) 1984-12-06
ES508655A0 (es) 1982-11-01
DD202018A5 (de) 1983-08-24
PT73338B (en) 1983-06-20
IL63285A (en) 1985-03-31
ES8300727A1 (es) 1982-11-01
IL63285A0 (en) 1981-10-30
HK98286A (en) 1986-12-24
FI74703C (fi) 1988-03-10
IE811567L (en) 1982-01-12
GR74333B (https=) 1984-06-25
DE3166003D1 (en) 1984-10-18
DE3026534A1 (de) 1982-03-18
CA1165317A (en) 1984-04-10
NZ197678A (en) 1984-12-14
ES8300726A1 (es) 1982-11-01
DK149851C (da) 1987-05-04
DK149851B (da) 1986-10-13
FI74703B (fi) 1987-11-30
GB2080296B (en) 1983-09-28
US4341778A (en) 1982-07-27
NO158578B (no) 1988-06-27
IE52508B1 (en) 1987-11-25
ZA814687B (en) 1983-03-30
ES8300725A1 (es) 1982-11-01
EP0043940B1 (de) 1984-09-12
DK306781A (da) 1982-01-13
PH17425A (en) 1984-08-08
ES508653A0 (es) 1982-11-01
NO812355L (no) 1982-01-13
ES508654A0 (es) 1982-11-01
EP0043940A1 (de) 1982-01-20
AU7273181A (en) 1982-09-16
ATE9336T1 (de) 1984-09-15
ES503837A0 (es) 1982-06-01
SG77686G (en) 1987-02-27
NO158578C (no) 1988-10-05
ES8205402A1 (es) 1982-06-01

Similar Documents

Publication Publication Date Title
KR850000755B1 (en) Process for preparing 3,1-benzoxazin-2-ones and acid addition salts thereof
EP0320118A3 (en) Peptides with collagenase inhibiting activity
TW368501B (en) 7-(2-aminoethyl)-benzothiazolones
ES8503666A1 (es) Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas
MY109337A (en) Phenoxyl-and phenoxyalkyl-piperidines as antiviral agents
MY100115A (en) Nitrogen containing heterocyclic compounds, and their production and use.
PT81004A (en) Process for preparing tricyclic oxindole useful as antiinflammatory agents
GR79023B (https=)
MX9702089A (es) Carboxamidas biciclicas como antagonistas de 5-ht1a.
ES471895A1 (es) Procedimiento para preparar derivados de benzamidina
ES8703834A1 (es) Metodo de obtener nuevos derivados diaminicos y sus sales
MX9701841A (es) Derivados aminoheterociclicos como agentes antitromboticos o anticoagulantes.
MY104164A (en) Heterocyclic compounds.

Legal Events

Date Code Title Description
PA0109 Patent application

St.27 status event code: A-0-1-A10-A12-nap-PA0109

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

T11-X000 Administrative time limit extension requested

St.27 status event code: U-3-3-T10-T11-oth-X000

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PG1605 Publication of application before grant of patent

St.27 status event code: A-2-2-Q10-Q13-nap-PG1605

PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PR0701 Registration of establishment

St.27 status event code: A-2-4-F10-F11-exm-PR0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U11-oth-PR1002

Fee payment year number: 1

PR1001 Payment of annual fee

St.27 status event code: A-4-4-U10-U11-oth-PR1001

Fee payment year number: 4

PC1903 Unpaid annual fee

St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 19890526

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

PC1903 Unpaid annual fee

St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 19890526