KR840004677A - 치환된 β-옥소-α-페닐-카바모일-피롤프로피오니트릴의 제조방법 - Google Patents

치환된 β-옥소-α-페닐-카바모일-피롤프로피오니트릴의 제조방법

Info

Publication number
KR840004677A
KR840004677A KR1019840002948A KR840002948A KR840004677A KR 840004677 A KR840004677 A KR 840004677A KR 1019840002948 A KR1019840002948 A KR 1019840002948A KR 840002948 A KR840002948 A KR 840002948A KR 840004677 A KR840004677 A KR 840004677A
Authority
KR
South Korea
Prior art keywords
lower alkyl
substituted
compounds
denotes
enol
Prior art date
Application number
KR1019840002948A
Other languages
English (en)
Other versions
KR840001132B1 (ko
Inventor
노드롭 워커 고돈
Original Assignee
시바-가이기 에이지
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 시바-가이기 에이지 filed Critical 시바-가이기 에이지
Application granted granted Critical
Publication of KR840001132B1 publication Critical patent/KR840001132B1/ko
Publication of KR840004677A publication Critical patent/KR840004677A/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1019840002948A 1979-06-11 1984-05-29 치환된 β-옥소-α-페닐-카바모일-피롤프로피오니트릴의 제조방법 KR840001132B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4606379A 1979-06-11 1979-06-11
US46063 1979-06-11
KR1019800002269A KR840001131B1 (ko) 1979-06-11 1980-06-10 치환된 β-옥소-α-페닐-카바모일-피롤 프로피오니트릴의 제조방법

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
KR1019800002269A Division KR840001131B1 (ko) 1979-06-11 1980-06-10 치환된 β-옥소-α-페닐-카바모일-피롤 프로피오니트릴의 제조방법

Publications (2)

Publication Number Publication Date
KR840001132B1 KR840001132B1 (ko) 1984-08-09
KR840004677A true KR840004677A (ko) 1984-10-22

Family

ID=21941390

Family Applications (4)

Application Number Title Priority Date Filing Date
KR1019800002269A KR840001131B1 (ko) 1979-06-11 1980-06-10 치환된 β-옥소-α-페닐-카바모일-피롤 프로피오니트릴의 제조방법
KR1019840002948A KR840001132B1 (ko) 1979-06-11 1984-05-29 치환된 β-옥소-α-페닐-카바모일-피롤프로피오니트릴의 제조방법
KR1019840002950A KR840001134B1 (ko) 1979-06-11 1984-05-29 치환된 β-옥소-α-페닐-카바모일-피롤프로피오니트릴의 제조방법
KR1019840002949A KR840001133B1 (ko) 1979-06-11 1984-05-29 치환된 β-옥소-α-페닐-카바모일-피롤프로 피오니트릴의 제조방법

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1019800002269A KR840001131B1 (ko) 1979-06-11 1980-06-10 치환된 β-옥소-α-페닐-카바모일-피롤 프로피오니트릴의 제조방법

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1019840002950A KR840001134B1 (ko) 1979-06-11 1984-05-29 치환된 β-옥소-α-페닐-카바모일-피롤프로피오니트릴의 제조방법
KR1019840002949A KR840001133B1 (ko) 1979-06-11 1984-05-29 치환된 β-옥소-α-페닐-카바모일-피롤프로 피오니트릴의 제조방법

Country Status (22)

Country Link
EP (2) EP0143142A3 (ko)
JP (1) JPS562961A (ko)
KR (4) KR840001131B1 (ko)
AT (1) ATE14724T1 (ko)
AU (1) AU539967B2 (ko)
CA (1) CA1133917A (ko)
CY (1) CY1426A (ko)
DD (1) DD151307A5 (ko)
DE (1) DE3070951D1 (ko)
DK (1) DK155996C (ko)
ES (1) ES492278A0 (ko)
FI (1) FI71129C (ko)
GR (1) GR69239B (ko)
HK (1) HK50288A (ko)
HU (1) HU182670B (ko)
IE (1) IE50288B1 (ko)
IL (1) IL60269A (ko)
KE (1) KE3795A (ko)
NO (1) NO155197C (ko)
NZ (1) NZ193995A (ko)
PT (1) PT71367A (ko)
ZA (1) ZA803461B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2127809B (en) * 1982-09-28 1986-03-12 Ciba Geigy Ag Certain b-oxo-a-carbamoyl-pyrrolepropionitriles
DE3247454A1 (de) * 1982-12-22 1984-06-28 Laboratorios Bago S.A., Buenos Aires Substituierte 3-phenyl-5-methyl-isoxazol-4-carboxy-anilide, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3525623A1 (de) * 1985-07-18 1987-01-22 Celamerck Gmbh & Co Kg Fungizid wirksame acrylsaeureamide
GB8619433D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
GB8619432D0 (en) * 1986-08-08 1986-09-17 Lilly Industries Ltd Pharmaceutical compounds
US4977181A (en) * 1987-12-18 1990-12-11 Ciba-Geigy Corporation Tromethamine salt of 1-methyl-beta-oxo-alpha-(phenylcarbamoyl)-2-pyrrolepropionitrile
IL92508A0 (en) * 1988-12-08 1990-08-31 Ciba Geigy Ag Novel alpha-cyano-beta-oxopropionamides
GR880100839A (el) * 1988-12-15 1994-03-31 Ciba Geigy Αλας τρομε?αμίνης του 1-με?ύλ-Β-ΟΞΟ-Α-(φαινυλοκαρβομουλό)-2-πυρρολοπροπιονιτριλίου.
AU625688B2 (en) * 1989-01-31 1992-07-16 Merrell Dow Pharmaceuticals Inc. Method of using aryl- or heteroaryl-1-alkyl-pyrrole-2- carboxylic acid compounds in the treatment of interleukin-1 mediated conditions
GB9720899D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
AU2003226651A1 (en) * 2002-03-19 2003-09-29 Bayer Chemicals Ag Squarylium dyes as a light-absorbing compound in the information layer of optical data carriers

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE861500C (de) * 1942-07-05 1953-01-05 Beth Ag Maschf Spuelluftfilter
GB1201061A (en) * 1966-08-26 1970-08-05 Endo Lab Oxo pyrroles and process for preparing same
ES448386A1 (es) * 1975-06-05 1978-04-16 Hoechst Ag Procedimiento para la preparacion de anilidas de acido 5-me-til-isoxazol-4-carboxilico.
NL186239B (nl) * 1975-06-05 Hoechst Ag Werkwijze voor de bereiding van een geneesmiddel met antiflogistische en/of analgetische werking, alsmede werkwijze voor de bereiding van een 2-hydroxyethylideencyaanazijnzuuranilide geschikt voor toepassing bij deze werkwijze.
DE2654797A1 (de) * 1976-12-03 1978-06-08 Hoechst Ag Verfahren zur herstellung von isoxazolderivaten

Also Published As

Publication number Publication date
IE801185L (en) 1980-12-11
KR830002708A (ko) 1983-05-30
KR840004678A (ko) 1984-10-22
NZ193995A (en) 1983-03-15
NO155197B (no) 1986-11-17
NO801733L (no) 1980-12-12
DK155996B (da) 1989-06-12
ES8104223A1 (es) 1981-04-01
KR840001134B1 (ko) 1984-08-09
KE3795A (en) 1988-03-11
JPS562961A (en) 1981-01-13
GR69239B (ko) 1982-05-11
ES492278A0 (es) 1981-04-01
AU5917380A (en) 1980-12-18
PT71367A (en) 1980-07-01
KR840001131B1 (ko) 1984-08-09
NO155197C (no) 1987-02-25
EP0143142A3 (de) 1985-07-17
DK250180A (da) 1980-12-12
CY1426A (en) 1988-09-02
JPH0351704B2 (ko) 1991-08-07
HK50288A (en) 1988-07-15
ZA803461B (en) 1981-06-24
AU539967B2 (en) 1984-10-25
DK155996C (da) 1989-11-06
CA1133917A (en) 1982-10-19
EP0143142A2 (de) 1985-06-05
EP0021207A1 (de) 1981-01-07
IL60269A (en) 1983-12-30
IL60269A0 (en) 1980-09-16
IE50288B1 (en) 1986-03-19
DE3070951D1 (en) 1985-09-12
FI71129C (fi) 1986-11-24
EP0021207B1 (de) 1985-08-07
ATE14724T1 (de) 1985-08-15
DD151307A5 (de) 1981-10-14
KR840001132B1 (ko) 1984-08-09
HU182670B (en) 1984-02-28
FI71129B (fi) 1986-08-14
KR840001133B1 (ko) 1984-08-09
FI801840A (fi) 1980-12-12

Similar Documents

Publication Publication Date Title
FI802203A (fi) Nya 2-alkoxifenyl-imidazo/4,5-b/pyridiner deras framstaellning och deras anvaendning saosom laekemedel
ES473074A1 (es) Un procedimiento para la preparacion de derivados de tieno- tiacina
KR840004678A (ko) 치환된 β-옥소-α-페닐-카바모일-피롤프로 피오니트릴의 제조방법
ES503583A0 (es) Un procedimiento para la preparacion de derivados de cefa- losporina
SE7903976L (sv) Nya purinderivat anvendbara sasom icke-adrenenergiska bronkodilatorer
SE7704240L (sv) Bis-kvaternera pyridinium-2-aldowim-salter och forfarande for framstellning derav
DE2963729D1 (en) New intermediates and their use for the preparation of new oxadiazolo-pyrimidine derivatives
FI810928L (fi) Saett och mellanprodukter foer framstaellning av 3,3'-azo-bis-(6-hydroxibensoesyra)
ES517995A0 (es) Un procedimiento para la preparacion de un compuesto de hidroxibencilaminobenceno, dotado de propiedades antiinflamatorias.
PT83064A (en) Process for the preparation of acid 4-oh-quinoline-carboxylic new derivatives relieved in the position 2 by a eventually converted in ether or ester dihydroxylade group
ATE7786T1 (de) Verwendung von wachstumsregulierenden alphaazolylglykolen.
FI850969L (fi) Monosilylerade aminofenyletylaminderivat, foerfarande foer deras framstaellning och deras anvaendning vid befraemjandet av tillvaext.
SE7908820L (sv) Imidazolyletoxiderivat av pyridin-5-metanoler och kinolin-3-metanoler
GB1094938A (en) Reactive dyes of the anthraquinone series
GB1081637A (en) Novel ketones and the preparation thereof
JPS6448049A (en) Organic nonlinear optical material and nonlinear optical element
FI893051A (fi) Oxiraner.

Legal Events

Date Code Title Description
A107 Divisional application of patent
G160 Decision to publish patent application
E701 Decision to grant or registration of patent right
GRNT Written decision to grant
FPAY Annual fee payment

Payment date: 19890705

Year of fee payment: 6

LAPS Lapse due to unpaid annual fee