GB2127809B - Certain b-oxo-a-carbamoyl-pyrrolepropionitriles - Google Patents

Certain b-oxo-a-carbamoyl-pyrrolepropionitriles

Info

Publication number
GB2127809B
GB2127809B GB08325355A GB8325355A GB2127809B GB 2127809 B GB2127809 B GB 2127809B GB 08325355 A GB08325355 A GB 08325355A GB 8325355 A GB8325355 A GB 8325355A GB 2127809 B GB2127809 B GB 2127809B
Authority
GB
United Kingdom
Prior art keywords
pyrrolepropionitriles
carbamoyl
oxo
certain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08325355A
Other versions
GB2127809A (en
GB8325355D0 (en
Inventor
Gordon Northrop Walker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of GB8325355D0 publication Critical patent/GB8325355D0/en
Publication of GB2127809A publication Critical patent/GB2127809A/en
Application granted granted Critical
Publication of GB2127809B publication Critical patent/GB2127809B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/337—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
GB08325355A 1982-09-28 1983-09-22 Certain b-oxo-a-carbamoyl-pyrrolepropionitriles Expired GB2127809B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42642582A 1982-09-28 1982-09-28

Publications (3)

Publication Number Publication Date
GB8325355D0 GB8325355D0 (en) 1983-10-26
GB2127809A GB2127809A (en) 1984-04-18
GB2127809B true GB2127809B (en) 1986-03-12

Family

ID=23690745

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08325355A Expired GB2127809B (en) 1982-09-28 1983-09-22 Certain b-oxo-a-carbamoyl-pyrrolepropionitriles

Country Status (8)

Country Link
EP (1) EP0156091B1 (en)
JP (2) JPS5978159A (en)
AU (1) AU576491B2 (en)
BE (1) BE897845A (en)
CA (1) CA1220214A (en)
DE (1) DE3334780A1 (en)
GB (1) GB2127809B (en)
IT (1) IT8349055A0 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644010A (en) * 1982-09-28 1987-02-17 Ciba-Geigy Corporation Certain β-oxo-α-carbamoylpyrrolepropionitriles
GB9720899D0 (en) * 1997-10-01 1997-12-03 Pharmacia & Upjohn Spa Condensed heterocyclic compounds
WO2002072527A2 (en) * 2001-03-13 2002-09-19 Protagen Aktiengesellschaft 1-butyric acid derivatives such as carbomethoxypropionyl cyanide or leflunomide derivatives, and the therapeutic use thereof
DE10112924A1 (en) * 2001-03-13 2002-10-02 Erich Eigenbrodt 1-butanoic acid derivatives, pharmaceutical compositions containing such derivatives and uses of such derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4256759A (en) * 1979-06-11 1981-03-17 Ciba-Geigy Corporation Alphacarbamoyl-pyrrolpropionitriles
CA1133917A (en) * 1979-06-11 1982-10-19 Gordon N. Walker Alphacarbamoyl-pyrrolpropionitriles, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application

Also Published As

Publication number Publication date
JPS60204757A (en) 1985-10-16
DE3334780A1 (en) 1984-03-29
EP0156091B1 (en) 1988-08-10
GB2127809A (en) 1984-04-18
JPS5978159A (en) 1984-05-04
IT8349055A0 (en) 1983-09-28
AU576491B2 (en) 1988-09-01
EP0156091A1 (en) 1985-10-02
AU2620684A (en) 1985-10-03
CA1220214A (en) 1987-04-07
GB8325355D0 (en) 1983-10-26
BE897845A (en) 1984-03-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19920922