KR840002816A - 이미다졸 또는 트리아졸 유도체, 이들의 산부가염 및 이들의 금속착염의 제조방법 - Google Patents
이미다졸 또는 트리아졸 유도체, 이들의 산부가염 및 이들의 금속착염의 제조방법 Download PDFInfo
- Publication number
- KR840002816A KR840002816A KR1019820005719A KR820005719A KR840002816A KR 840002816 A KR840002816 A KR 840002816A KR 1019820005719 A KR1019820005719 A KR 1019820005719A KR 820005719 A KR820005719 A KR 820005719A KR 840002816 A KR840002816 A KR 840002816A
- Authority
- KR
- South Korea
- Prior art keywords
- general formula
- group
- compound represented
- imidazole
- salts
- Prior art date
Links
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 title claims 6
- 239000002253 acid Substances 0.000 title claims 3
- -1 metal complex salts Chemical class 0.000 title claims 2
- 150000003839 salts Chemical class 0.000 title claims 2
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
- 229940042055 systemic antimycotics triazole derivative Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims 6
- 125000005843 halogen group Chemical group 0.000 claims 2
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical compound C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 claims 1
- 125000003342 alkenyl group Chemical group 0.000 claims 1
- 125000003545 alkoxy group Chemical group 0.000 claims 1
- 125000000304 alkynyl group Chemical group 0.000 claims 1
- 125000000753 cycloalkyl group Chemical group 0.000 claims 1
- 150000004678 hydrides Chemical class 0.000 claims 1
- 125000002883 imidazolyl group Chemical group 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 159000000000 sodium salts Chemical class 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
- 125000005156 substituted alkylene group Chemical group 0.000 claims 1
- 125000001425 triazolyl group Chemical group 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C07D233/61—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms not forming part of a nitro radical, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (1)
- 이미다졸 또는 1,2,4-트리아졸 또는 이들의 나트륨염을 하기 일반식(Ⅱ)의 화합물과 반응시키거나, 일반식 Q-A-CONHR1으로 표시되는 화합물을 수소화물의 존재하에 일반식 R2X로 표시되는 화합물과 반응시키거나, 또는 일반식 Q-A-COW로 표시되는 화합물을 일반식 R1R2NH로 표시되는 화합물과 반응시킴을 특징으로 하는 하기 일반식(Ⅰ)의 화합물, 이들의 산부기염 및 이들의 금속착염의 제조방법.상기 일반식에서, Z는 CH 또는 N이고, A는 임의의 측쇄를 가진 치환될 수 있는 알킬렌기이며, R1및 R2는 같거나 상이하며 임의로 치환된 알킬기, 시클로알킬기, 알켄일기 또는 알킨일기이고, Q는 이미다졸일기 또는 트리아졸일기 이며, W는 알콕시기 또는 할로겐원자와 같은 이탈기이고, X는 할로겐 원자이다.※참고사항:최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8138663 | 1981-12-22 | ||
| GB38663 | 1981-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR840002816A true KR840002816A (ko) | 1984-07-21 |
Family
ID=10526790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019820005719A KR840002816A (ko) | 1981-12-22 | 1982-12-21 | 이미다졸 또는 트리아졸 유도체, 이들의 산부가염 및 이들의 금속착염의 제조방법 |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0084236A3 (ko) |
| JP (1) | JPS58116470A (ko) |
| KR (1) | KR840002816A (ko) |
| AU (1) | AU538489B2 (ko) |
| BR (1) | BR8207436A (ko) |
| CA (1) | CA1186316A (ko) |
| CS (1) | CS236864B2 (ko) |
| DK (1) | DK563882A (ko) |
| ES (1) | ES518416A0 (ko) |
| GR (1) | GR77099B (ko) |
| IL (1) | IL67525A0 (ko) |
| NO (1) | NO824314L (ko) |
| OA (1) | OA07280A (ko) |
| PH (1) | PH18105A (ko) |
| PL (1) | PL239683A1 (ko) |
| PT (1) | PT76010B (ko) |
| ZA (1) | ZA829374B (ko) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0106515B1 (en) * | 1982-09-30 | 1988-12-28 | Pfizer Limited | Triazole anti-fungal agents |
| SU1313347A3 (ru) * | 1982-09-30 | 1987-05-23 | Пфайзер Корпорейшн (Фирма) | Способ получени производных триазола |
| DE3682711D1 (de) * | 1985-06-18 | 1992-01-16 | Ici Plc | Als fungizide verwendbare heterocyclische verbindungen. |
| ES2082743T3 (es) * | 1986-12-16 | 1996-04-01 | Zeneca Ltd | Derivados de pirrol y su uso en agricultura. |
| NZ229783A (en) * | 1988-07-22 | 1990-12-21 | Cl Pharma | Allylaminoethylazoles; fungicidal and antimycotic compositions, methods for preparation and combating fungi |
| DE4041173A1 (de) * | 1990-12-21 | 1992-06-25 | Henkel Kgaa | 1-mono- bzw. 1,3-bis-substituierte imidazoliumsalze und deren benzoanaloga, verfahren zur herstellung und ihre verwendung |
| PT1611088E (pt) * | 2003-04-07 | 2009-09-24 | Pharmacyclics Inc | Hidroxamatos como agentes terapêuticos |
| SI2099442T1 (sl) | 2006-12-26 | 2015-03-31 | Pharmacyclics, Inc. | Postopek uporabe inhibitorjev histon deacetilaze in spremljanje biomarkerjev v kombiniranjem zdravljenju |
| EA201201640A1 (ru) | 2007-01-30 | 2013-09-30 | Фармасайкликс, Инк. | Способы определения устойчивости рака к ингибиторам гистондеацетилазы |
| US8603521B2 (en) | 2009-04-17 | 2013-12-10 | Pharmacyclics, Inc. | Formulations of histone deacetylase inhibitor and uses thereof |
| CN103917231B (zh) | 2011-09-13 | 2016-09-28 | 药品循环有限责任公司 | 组蛋白脱乙酰酶抑制剂与苯达莫司汀的联合制剂及其用途 |
| JP6800750B2 (ja) | 2013-08-02 | 2020-12-16 | ファーマサイクリックス エルエルシー | 固形腫瘍の処置方法 |
| CN111574385B (zh) * | 2020-05-27 | 2022-10-04 | 石家庄万业化工科技有限公司 | 一种2-(2,4,6-三氯苯氧基)乙基丙胺的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4941434A (ko) * | 1972-08-11 | 1974-04-18 | ||
| GB1535777A (en) * | 1975-08-26 | 1978-12-13 | Ici Ltd | Imidazole and 1,2,4-triazole compounds and their use as pesticides |
| DE2845293A1 (de) * | 1978-10-18 | 1980-05-08 | Basf Ag | Alpha -azolyl- alpha -phenylessigsaeurederivate |
-
1982
- 1982-12-14 EP EP82306664A patent/EP0084236A3/en not_active Ceased
- 1982-12-20 OA OA57874A patent/OA07280A/xx unknown
- 1982-12-20 PH PH28299A patent/PH18105A/en unknown
- 1982-12-20 IL IL67525A patent/IL67525A0/xx unknown
- 1982-12-20 DK DK563882A patent/DK563882A/da not_active Application Discontinuation
- 1982-12-21 ES ES82518416A patent/ES518416A0/es active Granted
- 1982-12-21 GR GR70136A patent/GR77099B/el unknown
- 1982-12-21 PT PT76010A patent/PT76010B/pt unknown
- 1982-12-21 JP JP57223144A patent/JPS58116470A/ja active Pending
- 1982-12-21 KR KR1019820005719A patent/KR840002816A/ko unknown
- 1982-12-21 NO NO824314A patent/NO824314L/no unknown
- 1982-12-21 ZA ZA829374A patent/ZA829374B/xx unknown
- 1982-12-21 AU AU91733/82A patent/AU538489B2/en not_active Ceased
- 1982-12-21 CA CA000418220A patent/CA1186316A/en not_active Expired
- 1982-12-21 CS CS829471A patent/CS236864B2/cs unknown
- 1982-12-22 PL PL23968382A patent/PL239683A1/xx unknown
- 1982-12-22 BR BR8207436A patent/BR8207436A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO824314L (no) | 1983-06-23 |
| AU538489B2 (en) | 1984-08-16 |
| ZA829374B (en) | 1983-10-26 |
| PT76010A (en) | 1983-01-01 |
| CA1186316A (en) | 1985-04-30 |
| PL239683A1 (en) | 1984-02-27 |
| IL67525A0 (en) | 1983-05-15 |
| EP0084236A3 (en) | 1983-08-03 |
| PH18105A (en) | 1985-03-20 |
| DK563882A (da) | 1983-06-23 |
| ES8402581A1 (es) | 1984-02-01 |
| BR8207436A (pt) | 1983-10-18 |
| AU9173382A (en) | 1983-08-04 |
| JPS58116470A (ja) | 1983-07-11 |
| CS236864B2 (en) | 1985-05-15 |
| ES518416A0 (es) | 1984-02-01 |
| PT76010B (en) | 1985-10-04 |
| OA07280A (en) | 1984-08-31 |
| GR77099B (ko) | 1984-09-06 |
| EP0084236A2 (en) | 1983-07-27 |
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