KR840002654A - 파모티딘의 주사용 조성물의 제조방법 - Google Patents
파모티딘의 주사용 조성물의 제조방법 Download PDFInfo
- Publication number
- KR840002654A KR840002654A KR1019820005621A KR820005621A KR840002654A KR 840002654 A KR840002654 A KR 840002654A KR 1019820005621 A KR1019820005621 A KR 1019820005621A KR 820005621 A KR820005621 A KR 820005621A KR 840002654 A KR840002654 A KR 840002654A
- Authority
- KR
- South Korea
- Prior art keywords
- preparing
- pamotidine
- injectable composition
- pamotididine
- composition
- Prior art date
Links
- 239000007972 injectable composition Substances 0.000 title claims 3
- 238000000034 method Methods 0.000 title claims 3
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 4
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 claims 3
- CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 claims 3
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 3
- 239000007864 aqueous solution Substances 0.000 claims 3
- 229960005261 aspartic acid Drugs 0.000 claims 3
- 229960002989 glutamic acid Drugs 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- 229930195725 Mannitol Natural products 0.000 claims 1
- 238000004108 freeze drying Methods 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 239000000594 mannitol Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (3)
- 파모티딘의 수성조성뭍에 L-아스파르트산을 가함을 특징으로 하여 파모터딘의 주사용 수성조성물을 제조하는 방법.
- L-아스파르트산 및/또는 L-글루탐산을 가하여 파모티딘 수용액을 제조한 후 수용액을 동결건조시킴을 특징으로 하여 파모티딘의 동결건조된 주사용 조성물을 제조하는 방법.
- 파모티딘을, L-아스파르트산 및/또는 L-글루탐산을 가함으로써 물에 용해시키고 용액에 만니톨을 용해시킨 후 수용액을 동결건조시킴을 특징으로 하여 파모터딘의 동결건조된 주사용 조성물을 제조하는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP201934 | 1981-12-15 | ||
| JP56201934A JPS58103312A (ja) | 1981-12-15 | 1981-12-15 | 難溶性医薬品の注射剤用水溶液 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR840002654A true KR840002654A (ko) | 1984-07-16 |
| KR880001632B1 KR880001632B1 (en) | 1988-09-03 |
Family
ID=16449204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR8205621A KR880001632B1 (en) | 1981-12-15 | 1982-12-15 | Process for preparing famotidino injection composition |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS58103312A (ko) |
| KR (1) | KR880001632B1 (ko) |
| CA (1) | CA1184495A (ko) |
| ES (1) | ES8405613A1 (ko) |
| GR (1) | GR77823B (ko) |
| MX (1) | MX7581E (ko) |
| PT (1) | PT75985B (ko) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8703865A2 (es) * | 1985-06-28 | 1987-03-16 | Barisintex Sa | Perfeccionamientos en la patente de invencion n.544661 por: procedimiento de preparazcion de ascorbatos antagonistas h2-receptores. |
| US20040039036A1 (en) * | 2000-11-24 | 2004-02-26 | Yoshimi Hashimoto | Water-soluble liquid internal medicine |
| WO2002051411A1 (fr) * | 2000-12-22 | 2002-07-04 | Yamanouchi Pharmaceutical Co., Ltd. | Injections de famotidine |
| JP4828040B2 (ja) * | 2001-04-27 | 2011-11-30 | テルモ株式会社 | ファモチジン注射液 |
| WO2003055483A1 (fr) * | 2001-12-27 | 2003-07-10 | Terumo Kabushiki Kaisha | Solution d'injection de famotidine |
| AU2003235236A1 (en) * | 2002-05-13 | 2003-11-11 | Daiichi Pharmaceutical Co., Ltd. | Lyophilization product |
| CN111904936B (zh) * | 2020-08-28 | 2022-07-19 | 开封康诺药业有限公司 | 一种法莫替丁冻干粉针剂 |
| CN114681409A (zh) * | 2021-10-20 | 2022-07-01 | 海南倍特药业有限公司 | 一种注射用法莫替丁及其制备方法 |
| CN114028342B (zh) * | 2021-12-08 | 2023-04-28 | 广东彼迪药业有限公司 | 一种法莫替丁速崩颗粒、法莫替丁片及制备方法 |
-
1981
- 1981-12-15 JP JP56201934A patent/JPS58103312A/ja active Granted
-
1982
- 1982-12-14 ES ES518199A patent/ES8405613A1/es not_active Expired
- 1982-12-14 GR GR70069A patent/GR77823B/el unknown
- 1982-12-14 CA CA000417637A patent/CA1184495A/en not_active Expired
- 1982-12-14 PT PT75985A patent/PT75985B/pt unknown
- 1982-12-15 MX MX82101115U patent/MX7581E/es unknown
- 1982-12-15 KR KR8205621A patent/KR880001632B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES518199A0 (es) | 1984-06-16 |
| CA1184495A (en) | 1985-03-26 |
| MX7581E (es) | 1989-11-24 |
| PT75985B (en) | 1985-12-05 |
| PT75985A (en) | 1983-01-01 |
| KR880001632B1 (en) | 1988-09-03 |
| GR77823B (ko) | 1984-09-25 |
| ES8405613A1 (es) | 1984-06-16 |
| JPS6365047B2 (ko) | 1988-12-14 |
| JPS58103312A (ja) | 1983-06-20 |
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| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| G160 | Decision to publish patent application | ||
| O035 | Opposition [patent]: request for opposition | ||
| O122 | Withdrawal of opposition [patent] | ||
| E701 | Decision to grant or registration of patent right | ||
| O073 | Decision to grant registration after opposition [patent]: decision to grant registration | ||
| GRNT | Written decision to grant | ||
| FPAY | Annual fee payment |
Payment date: 19990413 Year of fee payment: 15 |
|
| EXPY | Expiration of term |