KR840000865B1 - β-락탐-함유 항균제의 제조방법 - Google Patents

β-락탐-함유 항균제의 제조방법 Download PDF

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Publication number
KR840000865B1
KR840000865B1 KR1019800000767A KR800000767A KR840000865B1 KR 840000865 B1 KR840000865 B1 KR 840000865B1 KR 1019800000767 A KR1019800000767 A KR 1019800000767A KR 800000767 A KR800000767 A KR 800000767A KR 840000865 B1 KR840000865 B1 KR 840000865B1
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KR
South Korea
Prior art keywords
formula
compound
reaction
general formula
lower alkyl
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Expired
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KR1019800000767A
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English (en)
Korean (ko)
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KR830001945A (ko
Inventor
포글리오 마우리지오
프란세쉬 지오반니
스카라필레 코시모
아르카모네 페데리코
산필리포 아우로라
Original Assignee
팜이탈리아 카를로엘바 에스피에이
죠르지오 오를란도
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Publication of KR830001945A publication Critical patent/KR830001945A/ko
Application granted granted Critical
Publication of KR840000865B1 publication Critical patent/KR840000865B1/ko
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
KR1019800000767A 1979-02-24 1980-02-25 β-락탐-함유 항균제의 제조방법 Expired KR840000865B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7906634 1979-02-24
GB7906634 1979-02-24

Publications (2)

Publication Number Publication Date
KR830001945A KR830001945A (ko) 1983-05-19
KR840000865B1 true KR840000865B1 (ko) 1984-06-20

Family

ID=10503424

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019800000767A Expired KR840000865B1 (ko) 1979-02-24 1980-02-25 β-락탐-함유 항균제의 제조방법

Country Status (4)

Country Link
JP (1) JPS55136288A (enrdf_load_stackoverflow)
KR (1) KR840000865B1 (enrdf_load_stackoverflow)
BE (1) BE881862A (enrdf_load_stackoverflow)
ZA (1) ZA80993B (enrdf_load_stackoverflow)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
NO831160L (no) * 1982-04-08 1983-10-10 Erba Farmitalia Fremstilling av substituerte penem-derivater
GB8300295D0 (en) * 1983-01-06 1983-02-09 Erba Farmitalia Penem esters
GB8416651D0 (en) * 1984-06-29 1984-08-01 Erba Farmitalia Penem derivatives
EP0567949B1 (en) 1992-04-28 2001-02-21 Tanabe Seiyaku Co., Ltd. Method for removing silyl protecting groups for hydroxy group
ATE219085T1 (de) 1997-12-29 2002-06-15 Res Corp Technologies Inc 2-beta-substituierte-6-alkylidenpenizillansäure derivate als beta-laktamase inhibitoren
US6407091B1 (en) 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
ES2272795T3 (es) 2001-07-24 2007-05-01 Southern Methodist University Foundation For Research 7-alquildieno-3-sustituidos-3-cefem-4-carboxilatos como inhibidores de beta-lactamasa.
JP2005525399A (ja) 2002-04-04 2005-08-25 アラムクス エルエルシー セリンおよびメタロ−β−ラクタマーゼの阻害剤

Also Published As

Publication number Publication date
KR830001945A (ko) 1983-05-19
BE881862A (fr) 1980-08-22
JPH03396B2 (enrdf_load_stackoverflow) 1991-01-07
ZA80993B (en) 1981-02-25
JPS55136288A (en) 1980-10-23

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