KR830010069A - 옥신돌 유도체의 제조방법 - Google Patents

옥신돌 유도체의 제조방법 Download PDF

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Publication number
KR830010069A
KR830010069A KR1019820001528A KR820001528A KR830010069A KR 830010069 A KR830010069 A KR 830010069A KR 1019820001528 A KR1019820001528 A KR 1019820001528A KR 820001528 A KR820001528 A KR 820001528A KR 830010069 A KR830010069 A KR 830010069A
Authority
KR
South Korea
Prior art keywords
alkyl
carbon atoms
formula
phenyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1019820001528A
Other languages
English (en)
Korean (ko)
Inventor
쿠흐 하인쯔
크루제 한스요르크
Original Assignee
하인리히 베커, 베르하르트 베크
헥스트 아크티엔 게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 하인리히 베커, 베르하르트 베크, 헥스트 아크티엔 게젤샤프트 filed Critical 하인리히 베커, 베르하르트 베크
Publication of KR830010069A publication Critical patent/KR830010069A/ko
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fats And Perfumes (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1019820001528A 1981-04-09 1982-04-07 옥신돌 유도체의 제조방법 Withdrawn KR830010069A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19813114351 DE3114351A1 (de) 1981-04-09 1981-04-09 "oxindol-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel mit neuroanaboler wirkung"
DE3114351.2 1981-04-09

Publications (1)

Publication Number Publication Date
KR830010069A true KR830010069A (ko) 1983-12-26

Family

ID=6129772

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019820001528A Withdrawn KR830010069A (ko) 1981-04-09 1982-04-07 옥신돌 유도체의 제조방법

Country Status (18)

Country Link
US (2) US4542148A (enExample)
EP (1) EP0062887B1 (enExample)
JP (1) JPS57179158A (enExample)
KR (1) KR830010069A (enExample)
AT (1) ATE8387T1 (enExample)
AU (1) AU548411B2 (enExample)
DE (2) DE3114351A1 (enExample)
DK (1) DK162682A (enExample)
ES (2) ES8307217A1 (enExample)
FI (1) FI821218L (enExample)
GR (1) GR75450B (enExample)
HU (1) HU186053B (enExample)
IL (1) IL65466A0 (enExample)
NO (1) NO821158L (enExample)
NZ (1) NZ200259A (enExample)
PH (1) PH19471A (enExample)
PT (1) PT74721B (enExample)
ZA (1) ZA822427B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619937A (en) * 1984-02-02 1986-10-28 Warner-Lambert Company Saturated bicyclic lactam acids and derivatives as cognition activators
DE3413572A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Oxindol-verbindungen zur behandlung der epilepsie
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
DE3529994A1 (de) * 1985-08-22 1987-02-26 Hoechst Ag Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE69031649T2 (de) * 1989-07-25 1998-02-26 Taiho Pharmaceutical Co Ltd Oxoindolderivate
SE514737C2 (sv) * 1994-03-22 2001-04-09 Sandvik Ab Belagt skärverktyg av hårdmetall
US5565483A (en) * 1995-06-07 1996-10-15 Bristol-Myers Squibb Company 3-substituted oxindole derivatives as potassium channel modulators
TW457233B (en) * 1996-10-11 2001-10-01 Bristol Myers Squibb Co Preparation of 3-fluoro oxindole derivatives
US7790726B2 (en) * 2005-08-16 2010-09-07 Chemocentryx, Inc. Monocyclic and bicyclic compounds and methods of use
EP2046739B1 (en) * 2006-07-24 2015-08-26 UCB Biopharma SPRL Substituted aniline derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3573310A (en) * 1967-09-28 1971-03-30 Miles Lab 1-substituted derivatives of 2-indolinone
US3558653A (en) * 1968-05-20 1971-01-26 Searle & Co Dialkylaminoalkyl-indolines
JPS4876863A (enExample) * 1972-01-22 1973-10-16
US3975531A (en) * 1973-10-02 1976-08-17 A. H. Robins Company, Incorporated 4-(5- And 7-)benzoylindolin-2-ones and pharmaceutical uses thereof
US4080330A (en) * 1975-06-23 1978-03-21 Delmar Chemicals Limited Phenylindolines and process for their production
US4110465A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 7-amino and 7-alkanoylamino 2-oxo-3-phenylindolines

Also Published As

Publication number Publication date
ATE8387T1 (de) 1984-07-15
JPS57179158A (en) 1982-11-04
IL65466A0 (en) 1982-07-30
ES511097A0 (es) 1983-06-16
DE3260356D1 (en) 1984-08-16
DK162682A (da) 1982-10-10
ZA822427B (en) 1983-02-23
NZ200259A (en) 1985-07-31
NO821158L (no) 1982-10-11
US4542148A (en) 1985-09-17
PT74721A (de) 1982-05-01
FI821218A7 (fi) 1982-10-10
PH19471A (en) 1986-05-14
AU548411B2 (en) 1985-12-12
EP0062887A1 (de) 1982-10-20
US4614739A (en) 1986-09-30
AU8248782A (en) 1983-04-21
ES8307217A1 (es) 1983-06-16
ES8401940A1 (es) 1984-01-01
ES521198A0 (es) 1984-01-01
EP0062887B1 (de) 1984-07-11
HU186053B (en) 1985-05-28
PT74721B (de) 1984-05-30
DE3114351A1 (de) 1982-11-04
FI821218L (fi) 1982-10-10
GR75450B (enExample) 1984-07-19
FI821218A0 (fi) 1982-04-06

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19820407

PG1501 Laying open of application
PC1203 Withdrawal of no request for examination