NO821158L - Oksindolderivater, fremgangsmaate til deres fremstilling og legemiddel med neuroanabol virkning som inneholder dem - Google Patents

Oksindolderivater, fremgangsmaate til deres fremstilling og legemiddel med neuroanabol virkning som inneholder dem

Info

Publication number
NO821158L
NO821158L NO821158A NO821158A NO821158L NO 821158 L NO821158 L NO 821158L NO 821158 A NO821158 A NO 821158A NO 821158 A NO821158 A NO 821158A NO 821158 L NO821158 L NO 821158L
Authority
NO
Norway
Prior art keywords
formula
atoms
phenyl
alkyl
substituted
Prior art date
Application number
NO821158A
Other languages
English (en)
Norwegian (no)
Inventor
Heinz Kuch
Hansjoerg Kruse
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO821158L publication Critical patent/NO821158L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/38—Oxygen atoms in positions 2 and 3, e.g. isatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fats And Perfumes (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Lubricants (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO821158A 1981-04-09 1982-04-06 Oksindolderivater, fremgangsmaate til deres fremstilling og legemiddel med neuroanabol virkning som inneholder dem NO821158L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813114351 DE3114351A1 (de) 1981-04-09 1981-04-09 "oxindol-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel mit neuroanaboler wirkung"

Publications (1)

Publication Number Publication Date
NO821158L true NO821158L (no) 1982-10-11

Family

ID=6129772

Family Applications (1)

Application Number Title Priority Date Filing Date
NO821158A NO821158L (no) 1981-04-09 1982-04-06 Oksindolderivater, fremgangsmaate til deres fremstilling og legemiddel med neuroanabol virkning som inneholder dem

Country Status (18)

Country Link
US (2) US4542148A (enExample)
EP (1) EP0062887B1 (enExample)
JP (1) JPS57179158A (enExample)
KR (1) KR830010069A (enExample)
AT (1) ATE8387T1 (enExample)
AU (1) AU548411B2 (enExample)
DE (2) DE3114351A1 (enExample)
DK (1) DK162682A (enExample)
ES (2) ES8307217A1 (enExample)
FI (1) FI821218L (enExample)
GR (1) GR75450B (enExample)
HU (1) HU186053B (enExample)
IL (1) IL65466A0 (enExample)
NO (1) NO821158L (enExample)
NZ (1) NZ200259A (enExample)
PH (1) PH19471A (enExample)
PT (1) PT74721B (enExample)
ZA (1) ZA822427B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4619937A (en) * 1984-02-02 1986-10-28 Warner-Lambert Company Saturated bicyclic lactam acids and derivatives as cognition activators
DE3413572A1 (de) * 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Oxindol-verbindungen zur behandlung der epilepsie
US4686224A (en) * 1984-10-31 1987-08-11 Pfizer Inc. Oxindole antiinflammatory agents
DE3529994A1 (de) * 1985-08-22 1987-02-26 Hoechst Ag Indolinonderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und deren verwendung
DE69031649T2 (de) * 1989-07-25 1998-02-26 Taiho Pharmaceutical Co Ltd Oxoindolderivate
SE514737C2 (sv) * 1994-03-22 2001-04-09 Sandvik Ab Belagt skärverktyg av hårdmetall
US5565483A (en) * 1995-06-07 1996-10-15 Bristol-Myers Squibb Company 3-substituted oxindole derivatives as potassium channel modulators
TW457233B (en) * 1996-10-11 2001-10-01 Bristol Myers Squibb Co Preparation of 3-fluoro oxindole derivatives
US7790726B2 (en) * 2005-08-16 2010-09-07 Chemocentryx, Inc. Monocyclic and bicyclic compounds and methods of use
EP2046739B1 (en) * 2006-07-24 2015-08-26 UCB Biopharma SPRL Substituted aniline derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3573310A (en) * 1967-09-28 1971-03-30 Miles Lab 1-substituted derivatives of 2-indolinone
US3558653A (en) * 1968-05-20 1971-01-26 Searle & Co Dialkylaminoalkyl-indolines
JPS4876863A (enExample) * 1972-01-22 1973-10-16
US3975531A (en) * 1973-10-02 1976-08-17 A. H. Robins Company, Incorporated 4-(5- And 7-)benzoylindolin-2-ones and pharmaceutical uses thereof
US4080330A (en) * 1975-06-23 1978-03-21 Delmar Chemicals Limited Phenylindolines and process for their production
US4110465A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 7-amino and 7-alkanoylamino 2-oxo-3-phenylindolines

Also Published As

Publication number Publication date
ATE8387T1 (de) 1984-07-15
JPS57179158A (en) 1982-11-04
IL65466A0 (en) 1982-07-30
KR830010069A (ko) 1983-12-26
ES511097A0 (es) 1983-06-16
DE3260356D1 (en) 1984-08-16
DK162682A (da) 1982-10-10
ZA822427B (en) 1983-02-23
NZ200259A (en) 1985-07-31
US4542148A (en) 1985-09-17
PT74721A (de) 1982-05-01
FI821218A7 (fi) 1982-10-10
PH19471A (en) 1986-05-14
AU548411B2 (en) 1985-12-12
EP0062887A1 (de) 1982-10-20
US4614739A (en) 1986-09-30
AU8248782A (en) 1983-04-21
ES8307217A1 (es) 1983-06-16
ES8401940A1 (es) 1984-01-01
ES521198A0 (es) 1984-01-01
EP0062887B1 (de) 1984-07-11
HU186053B (en) 1985-05-28
PT74721B (de) 1984-05-30
DE3114351A1 (de) 1982-11-04
FI821218L (fi) 1982-10-10
GR75450B (enExample) 1984-07-19
FI821218A0 (fi) 1982-04-06

Similar Documents

Publication Publication Date Title
JP3327473B2 (ja) インドール誘導体
US20040242589A1 (en) 3-arylsulfonyl-7-piperzinyl-indoles-benzofurans and -benzothiophenes with 5-ht6 receptor affinity for treating cns disorders
JPWO1995019343A1 (ja) インドール誘導体
EP2488486A1 (en) Hematopoietic growth factor mimetic small molecule compounds and their uses
EP0883613A1 (en) Sulfonamide derivatives as 5ht7 receptor antagonists
US5696122A (en) Indole and indoline derivatives as 5HT1D receptor antagonists
IE70927B1 (en) New (1-naphtyl) piperazine derivatives process for preparing these and pharmaceutical compositions containing them
CZ222392A3 (en) Amino substituted piperazine derivatives
EP0220066B1 (en) Carboxamide derivatives
EP0227241B1 (en) Medicinal indole and indazole keto sulphone derivatives
US5972937A (en) Heterocyclic compounds possessing 5HT2C receptor antagonist activity
JPH07291969A (ja) ３−インドリルピペリジン
US4542148A (en) 2-Oxo-3-phenyl indole derivatives, drugs having a neuroanabolic action containing them, and their use
US4695566A (en) 3-aminocarbonylmethoxy-5-phenylpyrazole compounds, antiarrythmic compositions containing them, and intermediates in their preparation
US4442102A (en) 1,5-Diphenylpyrazolin-3-one compounds, process and intermediates for preparation thereof and pharmaceutical compositions containing same
US3953467A (en) Pyrazole derivatives and process for preparing the same
MXPA02000731A (es) Derivados del indol.
US3972994A (en) Disubstituted azabicycloalkanes
EP1919896A1 (en) Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands.
NO138250B (no) Analogifremgangsmaate for fremstilling av farmakologisk aktive benzylaminer
EP0741132B1 (en) Indole derivatives
NZ200258A (en) Indole derivatives and pharmaceutical compositions
US3970663A (en) Certain amino-nicotinamide derivatives
NO881899L (no) Nye 2-aminoalkyl-4-benzyl-1-(2h)-ftalazino-derivater.
ES2389754T3 (es) Nuevos derivados de tiofendiamina con estructura urea