KR830009070A - 몰포린의 제조방법 - Google Patents

몰포린의 제조방법 Download PDF

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Publication number
KR830009070A
KR830009070A KR1019820001302A KR820001302A KR830009070A KR 830009070 A KR830009070 A KR 830009070A KR 1019820001302 A KR1019820001302 A KR 1019820001302A KR 820001302 A KR820001302 A KR 820001302A KR 830009070 A KR830009070 A KR 830009070A
Authority
KR
South Korea
Prior art keywords
formula
acid addition
compound
addition salt
prepared
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1019820001302A
Other languages
English (en)
Korean (ko)
Inventor
챞프만 화이트 앨런
브래들리 제랄드
Original Assignee
데이비드 이. 지벤스
죤 와이어스 앤드 브라더 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 데이비드 이. 지벤스, 죤 와이어스 앤드 브라더 리미티드 filed Critical 데이비드 이. 지벤스
Publication of KR830009070A publication Critical patent/KR830009070A/ko
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1019820001302A 1981-03-27 1982-03-26 몰포린의 제조방법 Ceased KR830009070A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8109713 1981-03-27
GB8109713 1981-03-27

Publications (1)

Publication Number Publication Date
KR830009070A true KR830009070A (ko) 1983-12-17

Family

ID=10520712

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019820001302A Ceased KR830009070A (ko) 1981-03-27 1982-03-26 몰포린의 제조방법

Country Status (19)

Country Link
US (2) US4409218A (OSRAM)
EP (2) EP0061899B1 (OSRAM)
JP (1) JPS57175176A (OSRAM)
KR (1) KR830009070A (OSRAM)
AT (2) ATE12230T1 (OSRAM)
AU (1) AU549554B2 (OSRAM)
CA (1) CA1171855A (OSRAM)
DE (2) DE3262596D1 (OSRAM)
DK (1) DK141282A (OSRAM)
ES (1) ES8304558A1 (OSRAM)
FI (1) FI821038A7 (OSRAM)
GB (2) GB2095673B (OSRAM)
GR (1) GR75908B (OSRAM)
HU (1) HU185703B (OSRAM)
IE (2) IE52502B1 (OSRAM)
IL (1) IL65213A (OSRAM)
PH (1) PH19897A (OSRAM)
PT (1) PT74656B (OSRAM)
ZA (1) ZA821376B (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0421687D0 (en) † 2004-09-30 2004-11-03 Johnson Matthey Plc Preparation of opiate analgesics
US20070213311A1 (en) * 2006-03-02 2007-09-13 Yun-Long Li Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
US20150307460A1 (en) * 2012-12-19 2015-10-29 Basf Se Substituted Triazoles and Imidazoles and Their Use as Fungicides
CN113234036B (zh) * 2021-05-12 2023-07-14 斯莱普泰(上海)生物医药科技有限公司 Nmda受体拮抗剂及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3112311A (en) * 1957-04-05 1963-11-26 Geigy Chem Corp 2-phenyl-5, 6-dimethyl-morpholines and 2-phenyl-5, 6-tetramethylene-morpholines
GB851311A (en) * 1958-04-02 1960-10-12 Geigy Ag J R Morpholine compounds and their production
DE2846567A1 (de) * 1978-10-26 1980-05-08 Basf Ag Neue 1,4-cycloalkanooxazepine, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
AU8116982A (en) 1982-09-30
GB2095673B (en) 1984-09-05
IE52502B1 (en) 1987-11-25
EP0061900A1 (de) 1982-10-06
DK141282A (da) 1982-09-28
GB2095672A (en) 1982-10-06
ZA821376B (en) 1983-10-26
FI821038L (fi) 1982-09-28
PH19897A (en) 1986-08-13
ATE12229T1 (de) 1985-04-15
PT74656B (en) 1983-10-20
US4409218A (en) 1983-10-11
US4387097A (en) 1983-06-07
AU549554B2 (en) 1986-01-30
IL65213A0 (en) 1982-05-31
IE52566B1 (en) 1987-12-09
CA1171855A (en) 1984-07-31
IL65213A (en) 1985-05-31
EP0061899A1 (en) 1982-10-06
ES510828A0 (es) 1983-03-16
EP0061900B1 (en) 1985-03-20
GB2095672B (en) 1984-10-24
FI821038A7 (fi) 1982-09-28
ATE12230T1 (de) 1985-04-15
GR75908B (OSRAM) 1984-08-02
IE820464L (en) 1982-09-27
ES8304558A1 (es) 1983-03-16
DE3262596D1 (en) 1985-04-25
DE3262595D1 (en) 1985-04-25
PT74656A (en) 1982-04-01
GB2095673A (en) 1982-10-06
IE820449L (en) 1982-09-27
FI821038A0 (fi) 1982-03-24
JPS57175176A (en) 1982-10-28
EP0061899B1 (en) 1985-03-20
HU185703B (en) 1985-03-28

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