FI821038A0 - Morfoliner - Google Patents

Morfoliner

Info

Publication number
FI821038A0
FI821038A0 FI821038A FI821038A FI821038A0 FI 821038 A0 FI821038 A0 FI 821038A0 FI 821038 A FI821038 A FI 821038A FI 821038 A FI821038 A FI 821038A FI 821038 A0 FI821038 A0 FI 821038A0
Authority
FI
Finland
Prior art keywords
alkyl
formula
activity
tetrahydrofurylmethyl
alkylmethyl
Prior art date
Application number
FI821038A
Other languages
English (en)
Other versions
FI821038L (fi
Inventor
Alan Chapman White
Gerald Bradley
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Publication of FI821038A0 publication Critical patent/FI821038A0/fi
Publication of FI821038L publication Critical patent/FI821038L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI821038A 1981-03-27 1982-03-24 Morfoliner FI821038L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8109713 1981-03-27

Publications (2)

Publication Number Publication Date
FI821038A0 true FI821038A0 (fi) 1982-03-24
FI821038L FI821038L (fi) 1982-09-28

Family

ID=10520712

Family Applications (1)

Application Number Title Priority Date Filing Date
FI821038A FI821038L (fi) 1981-03-27 1982-03-24 Morfoliner

Country Status (19)

Country Link
US (2) US4387097A (fi)
EP (2) EP0061900B1 (fi)
JP (1) JPS57175176A (fi)
KR (1) KR830009070A (fi)
AT (2) ATE12229T1 (fi)
AU (1) AU549554B2 (fi)
CA (1) CA1171855A (fi)
DE (2) DE3262596D1 (fi)
DK (1) DK141282A (fi)
ES (1) ES510828A0 (fi)
FI (1) FI821038L (fi)
GB (2) GB2095672B (fi)
GR (1) GR75908B (fi)
HU (1) HU185703B (fi)
IE (2) IE52502B1 (fi)
IL (1) IL65213A (fi)
PH (1) PH19897A (fi)
PT (1) PT74656B (fi)
ZA (1) ZA821376B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0421687D0 (en) * 2004-09-30 2004-11-03 Johnson Matthey Plc Preparation of opiate analgesics
US20070213311A1 (en) * 2006-03-02 2007-09-13 Yun-Long Li Modulators of 11-beta hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
EP2935224A1 (en) * 2012-12-19 2015-10-28 Basf Se New substituted triazoles and imidazoles and their use as fungicides
CN113234036B (zh) * 2021-05-12 2023-07-14 斯莱普泰(上海)生物医药科技有限公司 Nmda受体拮抗剂及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3112311A (en) * 1957-04-05 1963-11-26 Geigy Chem Corp 2-phenyl-5, 6-dimethyl-morpholines and 2-phenyl-5, 6-tetramethylene-morpholines
GB851311A (en) * 1958-04-02 1960-10-12 Geigy Ag J R Morpholine compounds and their production
DE2846567A1 (de) * 1978-10-26 1980-05-08 Basf Ag Neue 1,4-cycloalkanooxazepine, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
ATE12229T1 (de) 1985-04-15
GR75908B (fi) 1984-08-02
ATE12230T1 (de) 1985-04-15
ES8304558A1 (es) 1983-03-16
IE52502B1 (en) 1987-11-25
DE3262596D1 (en) 1985-04-25
EP0061900B1 (en) 1985-03-20
GB2095672A (en) 1982-10-06
IL65213A (en) 1985-05-31
IE820464L (en) 1982-09-27
CA1171855A (en) 1984-07-31
GB2095672B (en) 1984-10-24
AU549554B2 (en) 1986-01-30
US4387097A (en) 1983-06-07
HU185703B (en) 1985-03-28
IL65213A0 (en) 1982-05-31
EP0061899A1 (en) 1982-10-06
EP0061899B1 (en) 1985-03-20
IE820449L (en) 1982-09-27
GB2095673A (en) 1982-10-06
GB2095673B (en) 1984-09-05
PT74656A (en) 1982-04-01
JPS57175176A (en) 1982-10-28
DK141282A (da) 1982-09-28
AU8116982A (en) 1982-09-30
ZA821376B (en) 1983-10-26
IE52566B1 (en) 1987-12-09
DE3262595D1 (en) 1985-04-25
EP0061900A1 (en) 1982-10-06
KR830009070A (ko) 1983-12-17
FI821038L (fi) 1982-09-28
PT74656B (en) 1983-10-20
US4409218A (en) 1983-10-11
PH19897A (en) 1986-08-13
ES510828A0 (es) 1983-03-16

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Legal Events

Date Code Title Description
FA Application withdrawn

Owner name: JOHN WYETH & BROTHER LIMITED