ATE12229T1 - Morpholine. - Google Patents

Morpholine.

Info

Publication number
ATE12229T1
ATE12229T1 AT82301576T AT82301576T ATE12229T1 AT E12229 T1 ATE12229 T1 AT E12229T1 AT 82301576 T AT82301576 T AT 82301576T AT 82301576 T AT82301576 T AT 82301576T AT E12229 T1 ATE12229 T1 AT E12229T1
Authority
AT
Austria
Prior art keywords
alkyl
formula
activity
tetrahydrofurylmethyl
alkylmethyl
Prior art date
Application number
AT82301576T
Other languages
English (en)
Inventor
Alan Chapman White
Gerald Bradley
Original Assignee
Wyeth John & Brother Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth John & Brother Ltd filed Critical Wyeth John & Brother Ltd
Application granted granted Critical
Publication of ATE12229T1 publication Critical patent/ATE12229T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
AT82301576T 1981-03-27 1982-03-25 Morpholine. ATE12229T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8109713 1981-03-27

Publications (1)

Publication Number Publication Date
ATE12229T1 true ATE12229T1 (de) 1985-04-15

Family

ID=10520712

Family Applications (2)

Application Number Title Priority Date Filing Date
AT82301577T ATE12230T1 (de) 1981-03-27 1982-03-25 Morpholine.
AT82301576T ATE12229T1 (de) 1981-03-27 1982-03-25 Morpholine.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT82301577T ATE12230T1 (de) 1981-03-27 1982-03-25 Morpholine.

Country Status (19)

Country Link
US (2) US4409218A (de)
EP (2) EP0061900B1 (de)
JP (1) JPS57175176A (de)
KR (1) KR830009070A (de)
AT (2) ATE12230T1 (de)
AU (1) AU549554B2 (de)
CA (1) CA1171855A (de)
DE (2) DE3262595D1 (de)
DK (1) DK141282A (de)
ES (1) ES510828A0 (de)
FI (1) FI821038L (de)
GB (2) GB2095672B (de)
GR (1) GR75908B (de)
HU (1) HU185703B (de)
IE (2) IE52502B1 (de)
IL (1) IL65213A (de)
PH (1) PH19897A (de)
PT (1) PT74656B (de)
ZA (1) ZA821376B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0421687D0 (en) † 2004-09-30 2004-11-03 Johnson Matthey Plc Preparation of opiate analgesics
TW200808807A (en) * 2006-03-02 2008-02-16 Incyte Corp Modulators of 11-β hydroxyl steroid dehydrogenase type 1, pharmaceutical compositions thereof, and methods of using the same
CN104981459A (zh) * 2012-12-19 2015-10-14 巴斯夫欧洲公司 新型取代三唑类和咪唑类及其作为杀真菌剂的用途
CN113234036B (zh) * 2021-05-12 2023-07-14 斯莱普泰(上海)生物医药科技有限公司 Nmda受体拮抗剂及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3112311A (en) * 1957-04-05 1963-11-26 Geigy Chem Corp 2-phenyl-5, 6-dimethyl-morpholines and 2-phenyl-5, 6-tetramethylene-morpholines
GB851311A (en) * 1958-04-02 1960-10-12 Geigy Ag J R Morpholine compounds and their production
DE2846567A1 (de) * 1978-10-26 1980-05-08 Basf Ag Neue 1,4-cycloalkanooxazepine, verfahren zu deren herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0061899B1 (de) 1985-03-20
JPS57175176A (en) 1982-10-28
GB2095673A (en) 1982-10-06
AU8116982A (en) 1982-09-30
KR830009070A (ko) 1983-12-17
DE3262596D1 (en) 1985-04-25
FI821038L (fi) 1982-09-28
ES8304558A1 (es) 1983-03-16
DK141282A (da) 1982-09-28
IL65213A0 (en) 1982-05-31
GB2095672B (en) 1984-10-24
PT74656A (en) 1982-04-01
GR75908B (de) 1984-08-02
ATE12230T1 (de) 1985-04-15
IE820464L (en) 1982-09-27
EP0061899A1 (de) 1982-10-06
EP0061900B1 (de) 1985-03-20
DE3262595D1 (en) 1985-04-25
IE52566B1 (en) 1987-12-09
HU185703B (en) 1985-03-28
GB2095672A (en) 1982-10-06
ES510828A0 (es) 1983-03-16
IE52502B1 (en) 1987-11-25
FI821038A0 (fi) 1982-03-24
PH19897A (en) 1986-08-13
ZA821376B (en) 1983-10-26
US4387097A (en) 1983-06-07
AU549554B2 (en) 1986-01-30
IL65213A (en) 1985-05-31
US4409218A (en) 1983-10-11
CA1171855A (en) 1984-07-31
EP0061900A1 (de) 1982-10-06
PT74656B (en) 1983-10-20
IE820449L (en) 1982-09-27
GB2095673B (en) 1984-09-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee