KR20240167101A - Nkg2d, cd16 및 넥틴4에 결합하는 단백질 - Google Patents

Nkg2d, cd16 및 넥틴4에 결합하는 단백질 Download PDF

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KR20240167101A
KR20240167101A KR1020247038586A KR20247038586A KR20240167101A KR 20240167101 A KR20240167101 A KR 20240167101A KR 1020247038586 A KR1020247038586 A KR 1020247038586A KR 20247038586 A KR20247038586 A KR 20247038586A KR 20240167101 A KR20240167101 A KR 20240167101A
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그레고리 피. 창
안 에프. 청
윌리암 해니
브래들리 엠. 룬드
비안카 프린츠
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드래곤플라이 쎄라퓨틱스, 인크.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
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    • C07K16/283—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against Fc-receptors, e.g. CD16, CD32, CD64
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    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3084—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated gangliosides
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
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    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
KR1020247038586A 2017-09-07 2018-09-07 Nkg2d, cd16 및 넥틴4에 결합하는 단백질 Pending KR20240167101A (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201762555110P 2017-09-07 2017-09-07
US62/555,110 2017-09-07
US201762566824P 2017-10-02 2017-10-02
US62/566,824 2017-10-02
KR1020207009780A KR20200044957A (ko) 2017-09-07 2018-09-07 Nkg2d, cd16 및 종양-연관 항원에 결합하는 단백질
PCT/US2018/050073 WO2019051308A1 (en) 2017-09-07 2018-09-07 NKG2D, CD16 BINDING PROTEINS AND ANTIGEN ASSOCIATED WITH A TUMOR

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KR1020207009780A Ceased KR20200044957A (ko) 2017-09-07 2018-09-07 Nkg2d, cd16 및 종양-연관 항원에 결합하는 단백질
KR1020217007213A Ceased KR20210030503A (ko) 2017-09-07 2018-09-07 Nkg2d, cd16 및 종양-연관 항원에 결합하는 단백질

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KR1020217007213A Ceased KR20210030503A (ko) 2017-09-07 2018-09-07 Nkg2d, cd16 및 종양-연관 항원에 결합하는 단백질

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US (3) US20200277383A1 (https=)
EP (2) EP3925976A1 (https=)
JP (4) JP7431392B2 (https=)
KR (3) KR20240167101A (https=)
CN (3) CN111315782A (https=)
AU (3) AU2018329937B2 (https=)
BR (1) BR112020004489A2 (https=)
CA (2) CA3074840A1 (https=)
IL (2) IL273067A (https=)
MX (2) MX420258B (https=)
RU (1) RU2021110369A (https=)
SG (2) SG11202001930QA (https=)
WO (1) WO2019051308A1 (https=)

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