KR20240151258A - 3-치환된 1,2,4-옥사다이아졸의 결정질 형태 - Google Patents

3-치환된 1,2,4-옥사다이아졸의 결정질 형태 Download PDF

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Publication number
KR20240151258A
KR20240151258A KR1020247032835A KR20247032835A KR20240151258A KR 20240151258 A KR20240151258 A KR 20240151258A KR 1020247032835 A KR1020247032835 A KR 1020247032835A KR 20247032835 A KR20247032835 A KR 20247032835A KR 20240151258 A KR20240151258 A KR 20240151258A
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compound
crystalline compound
formula
producing
crystalline
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Korean (ko)
Inventor
포타열 고빈단 나이르 사시쿠마
시싸라마야 세티 수다르샨 나레마데팔리
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오리진 온콜로지 리미티드
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020247032835A 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태 Ceased KR20240151258A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN201741036169 2017-10-11
IN201741036169 2017-10-11
KR1020207009846A KR102838640B1 (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태
PCT/IB2018/057840 WO2019073399A1 (en) 2017-10-11 2018-10-10 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE SUBSTITUTED IN POSITION 3

Related Parent Applications (1)

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KR1020207009846A Division KR102838640B1 (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태

Publications (1)

Publication Number Publication Date
KR20240151258A true KR20240151258A (ko) 2024-10-17

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KR1020247032835A Ceased KR20240151258A (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태
KR1020207009846A Active KR102838640B1 (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태

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US (4) US11136300B2 (enExample)
EP (1) EP3694841A1 (enExample)
JP (2) JP7618445B2 (enExample)
KR (2) KR20240151258A (enExample)
CN (2) CN111194308A (enExample)
AU (2) AU2018348350B2 (enExample)
BR (1) BR112020006669A2 (enExample)
CA (1) CA3078872A1 (enExample)
EA (1) EA202090536A1 (enExample)
IL (2) IL273896B2 (enExample)
MY (1) MY201777A (enExample)
PH (1) PH12020550125A1 (enExample)
SG (1) SG11202003081WA (enExample)
WO (1) WO2019073399A1 (enExample)

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IL318981A (en) 2025-04-01
EP3694841A1 (en) 2020-08-19
JP2020536872A (ja) 2020-12-17
US11680051B2 (en) 2023-06-20
US11136300B2 (en) 2021-10-05
MY201777A (en) 2024-03-17
US12187689B2 (en) 2025-01-07
PH12020550125A1 (en) 2021-01-25
KR102838640B1 (ko) 2025-07-24
BR112020006669A2 (pt) 2020-09-24
JP2023109937A (ja) 2023-08-08
CA3078872A1 (en) 2019-04-18
IL273896B1 (en) 2025-04-01
CN117417308A (zh) 2024-01-19
KR20200068659A (ko) 2020-06-15
US20220048875A1 (en) 2022-02-17
EA202090536A1 (ru) 2020-07-22
AU2024202522A1 (en) 2024-05-09
AU2018348350A1 (en) 2020-04-02
US20230278970A1 (en) 2023-09-07
SG11202003081WA (en) 2020-05-28
US20250136562A1 (en) 2025-05-01
IL273896B2 (en) 2025-08-01
IL273896A (en) 2020-05-31
JP7618445B2 (ja) 2025-01-21
AU2018348350B2 (en) 2024-05-02
WO2019073399A1 (en) 2019-04-18
CN111194308A (zh) 2020-05-22
US20200239422A1 (en) 2020-07-30

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