KR20240058859A - 환각성 및 비환각성 세로토닌 수용체 작용제 및 이의 제조 및 사용 방법 - Google Patents
환각성 및 비환각성 세로토닌 수용체 작용제 및 이의 제조 및 사용 방법 Download PDFInfo
- Publication number
- KR20240058859A KR20240058859A KR1020247007510A KR20247007510A KR20240058859A KR 20240058859 A KR20240058859 A KR 20240058859A KR 1020247007510 A KR1020247007510 A KR 1020247007510A KR 20247007510 A KR20247007510 A KR 20247007510A KR 20240058859 A KR20240058859 A KR 20240058859A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- aka
- formula
- purified
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D345/00—Heterocyclic compounds containing rings having selenium or tellurium atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D517/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms
- C07D517/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having selenium, tellurium, or halogen atoms as ring hetero atoms in which the condensed system contains two hetero rings
- C07D517/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (41)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163232614P | 2021-08-12 | 2021-08-12 | |
| US202163232548P | 2021-08-12 | 2021-08-12 | |
| US202163232539P | 2021-08-12 | 2021-08-12 | |
| US63/232,548 | 2021-08-12 | ||
| US63/232,539 | 2021-08-12 | ||
| US63/232,614 | 2021-08-12 | ||
| US202163238133P | 2021-08-28 | 2021-08-28 | |
| US202163238135P | 2021-08-28 | 2021-08-28 | |
| US202163238134P | 2021-08-28 | 2021-08-28 | |
| US202163238132P | 2021-08-28 | 2021-08-28 | |
| US63/238,133 | 2021-08-28 | ||
| US63/238,134 | 2021-08-28 | ||
| US63/238,132 | 2021-08-28 | ||
| US63/238,135 | 2021-08-28 | ||
| US202163239965P | 2021-09-02 | 2021-09-02 | |
| US202163239963P | 2021-09-02 | 2021-09-02 | |
| US202163239964P | 2021-09-02 | 2021-09-02 | |
| US63/239,963 | 2021-09-02 | ||
| US63/239,965 | 2021-09-02 | ||
| US63/239,964 | 2021-09-02 | ||
| US202163285656P | 2021-12-03 | 2021-12-03 | |
| US202163285688P | 2021-12-03 | 2021-12-03 | |
| US202163285679P | 2021-12-03 | 2021-12-03 | |
| US63/285,688 | 2021-12-03 | ||
| US63/285,656 | 2021-12-03 | ||
| US63/285,679 | 2021-12-03 | ||
| US202163292567P | 2021-12-22 | 2021-12-22 | |
| US63/292,567 | 2021-12-22 | ||
| US202263301196P | 2022-01-20 | 2022-01-20 | |
| US63/301,196 | 2022-01-20 | ||
| US202263314378P | 2022-02-26 | 2022-02-26 | |
| US202263314377P | 2022-02-26 | 2022-02-26 | |
| US202263314379P | 2022-02-26 | 2022-02-26 | |
| US63/314,379 | 2022-02-26 | ||
| US63/314,378 | 2022-02-26 | ||
| US63/314,377 | 2022-02-26 | ||
| US202263319200P | 2022-03-11 | 2022-03-11 | |
| US63/319,200 | 2022-03-11 | ||
| US202263325515P | 2022-03-30 | 2022-03-30 | |
| US63/325,515 | 2022-03-30 | ||
| PCT/US2022/040048 WO2023018864A1 (en) | 2021-08-12 | 2022-08-11 | Hallucinogenic and non-hallucinogenic serotonin receptor agonists and methods of making and using the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20240058859A true KR20240058859A (ko) | 2024-05-03 |
Family
ID=85201052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247007510A Pending KR20240058859A (ko) | 2021-08-12 | 2022-08-11 | 환각성 및 비환각성 세로토닌 수용체 작용제 및 이의 제조 및 사용 방법 |
Country Status (8)
| Country | Link |
|---|---|
| US (8) | US11780807B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP4384172A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2024531229A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20240058859A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2022328217A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3229044A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL310378A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2023018864A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3519816A4 (en) | 2016-09-29 | 2020-05-06 | The Regents of the University of California | CONNECTIONS FOR INCREASING NEURONAL PLASTICITY |
| KR102946120B1 (ko) | 2019-02-27 | 2026-03-30 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 뇌 장애를 치료하기 위한 아제피노-인돌 및 다른 헤테로사이클 |
| WO2022120181A1 (en) * | 2020-12-03 | 2022-06-09 | Mydecine Innovations Group Inc. | Novel psilocin analog compositions and methods of synthesizing the same |
| WO2022221415A2 (en) | 2021-04-13 | 2022-10-20 | The Regents Of The University Of California | Tetracyclic compounds for treating brain disorders |
| WO2022246554A1 (en) * | 2021-05-26 | 2022-12-01 | Bright Minds Biosciences Inc. | Heterocyclic compounds and methods of preparation thereof |
| WO2023018864A1 (en) | 2021-08-12 | 2023-02-16 | Psilosterics, Llc | Hallucinogenic and non-hallucinogenic serotonin receptor agonists and methods of making and using the same |
| JP2025502615A (ja) | 2021-12-15 | 2025-01-28 | デリックス セラピューティクス，インク． | フェノキシおよびベンジルオキシ置換サイコプラストゲンならびにその使用 |
| JP2025501141A (ja) | 2021-12-24 | 2025-01-17 | サイロ プロプリエタリー リミテッド | 化合物 |
| US12065404B2 (en) | 2022-03-18 | 2024-08-20 | Enveric Biosciences Canada Inc. | C4-carboxylic acid-substituted tryptamine derivatives and methods of using |
| AU2023235712A1 (en) * | 2022-03-18 | 2024-11-07 | Enveric Biosciences Canada Inc. | C4-substituted tryptamine derivatives and methods of using |
| JP2026515993A (ja) * | 2023-05-04 | 2026-05-19 | ギルガメッシュ・ファーマシューティカルズ・インコーポレイテッド | 新規エルゴリン及び気分障害を処置する方法 |
| EP4735441A1 (en) | 2023-06-28 | 2026-05-06 | Psylo Pty Ltd | Pyrrolopyridine compounds for the treatment of mental illnesses |
| JP2026524104A (ja) | 2023-06-28 | 2026-07-17 | サイロ プロプリエタリー リミテッド | 化合物 |
| WO2025042885A1 (en) * | 2023-08-21 | 2025-02-27 | Kuleon Llc | Salts and solid forms of benzothiophene and benzoselenophene serotonin receptor modulators |
| WO2025049510A1 (en) * | 2023-08-29 | 2025-03-06 | Caamtech, Inc. | 4-hydroxy-n-ethyltryptamine |
| WO2025122513A1 (en) * | 2023-12-04 | 2025-06-12 | Delix Therapeutics, Inc. | Methods of treating neuropsychiatric disorders with non-hallucinogenic tryptamines |
| WO2026137050A1 (en) * | 2024-12-24 | 2026-07-02 | Psylo Pty Ltd | Compounds |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3636218A (en) | 1969-10-22 | 1972-01-18 | Colgate Palmolive Co | Pharmaceutical compositions and methods containing 1 2 3 4-tetrahydrobenzothieno(2 3-c)pyridines |
| US4137414A (en) | 1977-09-26 | 1979-01-30 | G. D. Searle & Co. | 5-Substituted-2-phenylbenzo[b]thiophene-3-alkylamines and related compounds |
| EP0204349A3 (de) | 1985-06-01 | 1990-01-03 | Dr. Karl Thomae GmbH | Neue heteroaromatische Aminderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| GB9221761D0 (en) | 1992-10-16 | 1992-12-02 | Glaxo Group Ltd | Chemical compounds |
| JPH09510216A (ja) | 1994-03-11 | 1997-10-14 | イーライ・リリー・アンド・カンパニー | ５−ｈｔ▲下２ｂ▼受容体に関連する病態を治療するための方法 |
| JPH09124643A (ja) * | 1995-08-14 | 1997-05-13 | Bristol Myers Squibb Co | 抗うつ作用を有する１−アリールアルキル−４−（アルコキシピリジニル）−又は４−（アルコキシピリミジニル）ピペラジン誘導体 |
| JP2001501946A (ja) | 1996-10-08 | 2001-02-13 | イーライ・リリー・アンド・カンパニー | 新規セロトニン５―ｈｔ▲下１ｆ▼アゴニスト |
| JP2003521443A (ja) * | 1998-06-19 | 2003-07-15 | ハー・ルンドベック・アクチエゼルスカベット | ４，５，６及び７−インドール及びインドリン誘導体、その製造方法及びその使用方法 |
| DE19948417A1 (de) * | 1999-10-07 | 2001-04-19 | Morphochem Ag | Imidazol-Derivate und ihre Verwendung als Arzneimittel |
| US7276603B2 (en) * | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
| PE20061130A1 (es) | 2004-11-19 | 2007-01-05 | Arena Pharm Inc | Derivados de 3-fenil-pirazol como moduladores del receptor de serotonina 5-ht2a |
| CA2640678C (en) | 2006-02-03 | 2015-03-31 | Bionomics Limited | Substituted benzofurans, benzothiophenes, benzoselenophenes and indoles and their use as tubulin polymerisation inhibitors |
| WO2007149728A2 (en) | 2006-06-20 | 2007-12-27 | Alcon Research, Ltd. | Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma |
| EP2762472B1 (en) | 2011-09-28 | 2017-05-24 | Industry-Academia Cooperation Group of Sejong University | Selenophene-fused aromatic compound and manufacturing method thereof |
| WO2014018888A1 (en) * | 2012-07-26 | 2014-01-30 | Confluence Life Sciences Inc. | 4-alkoxy/aralkoxy-5-substituted-pyrrolopyrimidine compounds as tak1 inhibitors in disease treatment |
| KR20220054908A (ko) | 2014-04-04 | 2022-05-03 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 유기 화합물 |
| EP3519816A4 (en) * | 2016-09-29 | 2020-05-06 | The Regents of the University of California | CONNECTIONS FOR INCREASING NEURONAL PLASTICITY |
| WO2018133835A1 (en) * | 2017-01-20 | 2018-07-26 | National Institute Of Biological Sciences, Beijing | Nucleoside analogue regulating mammalian circadian rhythm |
| JP7273731B2 (ja) * | 2017-02-09 | 2023-05-15 | カームテック、エルエルシー | シロシビン誘導体を含む組成物及び方法 |
| KR102946120B1 (ko) | 2019-02-27 | 2026-03-30 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 뇌 장애를 치료하기 위한 아제피노-인돌 및 다른 헤테로사이클 |
| GB201907871D0 (en) * | 2019-06-03 | 2019-07-17 | Small Pharma Ltd | Therapeutic compositions |
| WO2021041407A1 (en) | 2019-08-25 | 2021-03-04 | Caamtech Llc | Alkyl quarternary ammonium tryptamines and their therapeutic uses |
| KR102966320B1 (ko) | 2019-12-20 | 2026-05-19 | 보에 테크놀로지 그룹 컴퍼니 리미티드 | 추론 연산 장치, 모델 훈련 장치, 및 추론 연산 시스템 |
| MX2022009527A (es) | 2020-02-04 | 2022-11-16 | Mindset Pharma Inc | Derivados de la psilocina como agentes psicodelicos serotoninergicos para el tratamiento de trastornos del snc. |
| JP2023530665A (ja) | 2020-06-10 | 2023-07-19 | デリックス セラピューティクス，インク． | イソトリプタミンサイコプラストゲンおよびその使用 |
| DK4172145T3 (da) | 2020-06-30 | 2026-07-20 | Reunion Neuroscience Inc | Tryptamin-prodrugs som serotonin-receptor-aktivatorer til behandling af f.eks. depression |
| WO2022120181A1 (en) | 2020-12-03 | 2022-06-09 | Mydecine Innovations Group Inc. | Novel psilocin analog compositions and methods of synthesizing the same |
| CN117177959A (zh) | 2021-03-18 | 2023-12-05 | 赛本爱尔兰有限公司 | 裸头草碱类似物、盐、组合物和使用方法 |
| WO2022246554A1 (en) | 2021-05-26 | 2022-12-01 | Bright Minds Biosciences Inc. | Heterocyclic compounds and methods of preparation thereof |
| WO2023018864A1 (en) | 2021-08-12 | 2023-02-16 | Psilosterics, Llc | Hallucinogenic and non-hallucinogenic serotonin receptor agonists and methods of making and using the same |
| US20250051276A1 (en) | 2021-12-15 | 2025-02-13 | Delix Therapeutics, Inc. | Aryloxy psychoplastogens and uses thereof |
| WO2023122135A1 (en) | 2021-12-22 | 2023-06-29 | Kuleon Llc | Serotonin receptor agonists and methods of making and using the same |
| JP2025501141A (ja) | 2021-12-24 | 2025-01-17 | サイロ プロプリエタリー リミテッド | 化合物 |
| EP4522167A1 (en) | 2022-05-10 | 2025-03-19 | Mydecine Innovations Group Inc. | Novel psilocin prodrug compounds and methods of synthesizing the same |
| AU2023323907A1 (en) * | 2022-08-11 | 2025-02-20 | Gilgamesh Pharmaceuticals, Inc. | Tryptamines and methods of treating mood disorders |
| EP4735441A1 (en) | 2023-06-28 | 2026-05-06 | Psylo Pty Ltd | Pyrrolopyridine compounds for the treatment of mental illnesses |
| WO2025042884A2 (en) * | 2023-08-21 | 2025-02-27 | Kuleon Llc | Serotonin receptor modulators for the treatment of addictions and overdoses |
| WO2025042885A1 (en) * | 2023-08-21 | 2025-02-27 | Kuleon Llc | Salts and solid forms of benzothiophene and benzoselenophene serotonin receptor modulators |
-
2022
- 2022-08-11 WO PCT/US2022/040048 patent/WO2023018864A1/en not_active Ceased
- 2022-08-11 CA CA3229044A patent/CA3229044A1/en active Pending
- 2022-08-11 AU AU2022328217A patent/AU2022328217A1/en active Pending
- 2022-08-11 IL IL310378A patent/IL310378A/en unknown
- 2022-08-11 KR KR1020247007510A patent/KR20240058859A/ko active Pending
- 2022-08-11 JP JP2024508631A patent/JP2024531229A/ja active Pending
- 2022-08-11 EP EP22856602.2A patent/EP4384172A4/en active Pending
-
2023
- 2023-04-25 US US18/306,652 patent/US11780807B2/en active Active
- 2023-07-28 US US18/360,976 patent/US12187678B2/en active Active
- 2023-12-12 US US18/536,542 patent/US12012380B1/en active Active
-
2024
- 2024-06-13 US US18/741,888 patent/US12275701B2/en active Active
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| US20240124397A1 (en) | 2024-04-18 |
| US20250282722A1 (en) | 2025-09-11 |
| US12187678B2 (en) | 2025-01-07 |
| WO2023018864A1 (en) | 2023-02-16 |
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| US20250091991A1 (en) | 2025-03-20 |
| US12275701B2 (en) | 2025-04-15 |
| EP4384172A4 (en) | 2025-07-30 |
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| US12344582B2 (en) | 2025-07-01 |
| US20230257346A1 (en) | 2023-08-17 |
| US20260092034A1 (en) | 2026-04-02 |
| EP4384172A1 (en) | 2024-06-19 |
| US12668574B2 (en) | 2026-06-30 |
| JP2024531229A (ja) | 2024-08-29 |
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