KR20240037892A - 클라우딘 18.2 t 세포-항원 커플러 및 이의 용도 - Google Patents

클라우딘 18.2 t 세포-항원 커플러 및 이의 용도 Download PDF

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KR20240037892A
KR20240037892A KR1020237045349A KR20237045349A KR20240037892A KR 20240037892 A KR20240037892 A KR 20240037892A KR 1020237045349 A KR1020237045349 A KR 1020237045349A KR 20237045349 A KR20237045349 A KR 20237045349A KR 20240037892 A KR20240037892 A KR 20240037892A
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sequence
seq
binding domain
antigen binding
claudin
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Korean (ko)
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안드레아스 베이더
크리스토퍼 더블유 헬센
필버트 아이피
타니아 베나타르
링 왕
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트리움비라 이뮤놀로직스 유에스에이, 인크.
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Publication of KR20240037892A publication Critical patent/KR20240037892A/ko
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A61K39/4611—
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    • A61K39/464402—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
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    • A61K40/33—Antibodies; T-cell engagers
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    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
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KR1020237045349A 2021-06-01 2022-06-01 클라우딘 18.2 t 세포-항원 커플러 및 이의 용도 Pending KR20240037892A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202163202211P 2021-06-01 2021-06-01
US63/202,211 2021-06-01
US202163263809P 2021-11-09 2021-11-09
US63/263,809 2021-11-09
US202263362594P 2022-04-06 2022-04-06
US63/362,594 2022-04-06
PCT/US2022/031836 WO2022256449A1 (en) 2021-06-01 2022-06-01 Claudin 18.2 t cell-antigen couplers and uses thereof

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Publication Number Publication Date
KR20240037892A true KR20240037892A (ko) 2024-03-22

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KR1020237045349A Pending KR20240037892A (ko) 2021-06-01 2022-06-01 클라우딘 18.2 t 세포-항원 커플러 및 이의 용도

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US (2) US12016923B2 (https=)
EP (1) EP4347660A4 (https=)
JP (1) JP2024522357A (https=)
KR (1) KR20240037892A (https=)
AU (1) AU2022283819A1 (https=)
CA (1) CA3173810A1 (https=)
WO (1) WO2022256449A1 (https=)

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